CAS 2240-28-0

(11beta,16beta)-9-fluoro-11,17-diidrossi-16-metil-3,20-diossopregna-1,4-dien-21-il pentanoato

Descrizione:

La sostanza chimica nota come "(11beta,16beta)-9-fluoro-11,17-diidrossi-16-metil-3,20-diossopregna-1,4-dien-21-il pentanoato," con il numero CAS 2240-28-0, è un corticosteroide sintetico. Mostra proprietà anti-infiammatorie e immunosoppressive, rendendola utile in varie applicazioni terapeutiche, in particolare nel trattamento di condizioni come allergie, asma e disturbi autoimmuni. La struttura di questo composto presenta un atomo di fluoro, che ne aumenta la potenza e la stabilità metabolica rispetto ad altri corticosteroidi. La presenza di gruppi idrossilici contribuisce alla sua solubilità e attività biologica. Inoltre, il gruppo estere pentanoato può influenzare la sua farmacocinetica, consentendo potenzialmente un'azione prolungata nel corpo. Come con molti corticosteroidi, è essenziale monitorare gli effetti collaterali, inclusi i potenziali impatti sul metabolismo e sulla funzione immunitaria. In generale, questo composto esemplifica le modifiche strutturali che possono migliorare l'efficacia terapeutica dei farmaci a base di steroidi.

Formula: C₂₇H₃₇FO₆

InChI: InChI=1/C27H37FO6/c1-5-6-7-23(32)34-15-22(31)27(33)16(2)12-20-19-9-8-17-13-18(29)10-11-24(17,3)26(19,28)21(30)14-25(20,27)4/h10-11,13,16,19-21,30,33H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1

InChI key: InChIKey=FEROCCAEIIKMJT-SUYDQAKGSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@H](C)[C@@]2(C(COC(CCCC)=O)=O)O)[H]

Sinonimi:

• (11β,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxopentyl)oxy]pregna-1,4-diene-3,20-dione
• Betamethasone 21-valerate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-((1-oxopentyl)oxy)-, (11beta,16beta)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (11β,16β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17-dihydroxy-16beta-methyl-21-((1-oxopentyl)oxy)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 21-valerate
• BETAMETHASONE VALERATE RELATED COMPOUND A (50 MG) (BETAMETHASONE 21-VALERATE) (AS)
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxopentyl)oxy-, (11.beta.,16.beta.)-
• BetaMethasone Valerate Related CoMpound A
• Betamethasone Valerate Impurity E
• Betamethasone Valerate EP Impurity E
• Betamethasone Valerate impurity 4/Betamethasone Valerate EP Impurity E/Betamethasone 21-Valerate
• Betamethasone Valerate EP Impurity E (Betamethasone 21-Valerate)
• Betamethasone 21-valerate CRS
• Betamethasone impurity E (PhEur)

Betamethasone Valerate EP Impurity E

CAS: 2240-28-0

Formula: C₂₇H₃₇FO₆

Peso molecolare: 476.59

Ref: ST-EA-CP-B5005

BETAMETHASONE 21-VALERATE CRS

CAS: 2240-28-0

BETAMETHASONE 21-VALERATE CRS

Formula: C₂₇H₃₇FO₆

Peso molecolare: 476.5775

Ref: 41-B1055000

Betamethasone 21-valerate

CAS: 2240-28-0

Betamethasone 21-valerate

Colore e forma: White

Ref: 47-43

Betamethasone Valerate Related Compound A (9-Fluoro-11β,17-dihydroxy-16β-methyl-3,20-dioxopregna-1,4-diene-21-yl valerate)

CAS: 2240-28-0

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₇H₃₇FO₆

Colore e forma: White Fine Powder

Peso molecolare: 476.25742

Ref: 45-1069018

Betamethasone 21-valerate

CAS: 2240-28-0

Betamethasone 21-valerate

Purezza: ≥95%

Ref: 54-BI12237

Betamethasone Valerate EP Impurity E (Betamethasone Valerate USP Related Compound A, Betamethasone 21-Valerate)

CAS: 2240-28-0

Formula: C₂₇H₃₇FO₆

Colore e forma: White To Off-White Solid

Peso molecolare: 476.59

Ref: 4Z-B-065012

9-Fluoro-11β,17-dihydroxy-16β-methyl-3,20-dioxopregna-1,4-dien-21-yl Pentanoate (Betamethasone 21-Valerate)

Prodotto controllato

CAS: 2240-28-0

Formula: C₂₇H₃₇FO₆

Colore e forma: Neat

Peso molecolare: 476.58

Ref: 86-MM0203.01

Betamethasone 21-Valerate

CAS: 2240-28-0

Impurity Betamethasone Valerate EP Impurity E
Applications Betamethasone 21-Valerate (Betamethasone Valerate EP Impurity E) is an isomeric impurity of Betamethasone 17-Valerate (B327075), as an corticosteroid. Betamethasone 21-Valerate was generated in the stress study of the active drug Betamethasone 17-Valerate (B327075).
References Caron, J.C., et al.: J. Pharmaceut. Sci., 73, 1703 (1984); Stouch, T.R., et al.: J. Med. Chem., 29, 2125 (1986);

Formula: C₂₇H₃₇FO₆

Colore e forma: White

Peso molecolare: 476.58

Ref: TR-B327080

Betamethasone 21-valerate

CAS: 2240-28-0

Betamethasone 21-valerate is a corticosteroid ester with anti-inflammatory properties.

Formula: C₂₇H₃₇FO₆

Colore e forma: Solid

Peso molecolare: 476.58

Ref: TM-T200792

Betamethasone-d9 21-Valerate

Prodotto controllato

CAS: 2240-28-0

Formula: C₂₇D₉H₂₈FO₆

Colore e forma: Neat

Peso molecolare: 485.633

Ref: TR-B327082

Betamethasone valerate related compound A

Prodotto controllato

CAS: 2240-28-0

Betamethasone valerate related compound A is a corticosteroid compound that is used in the treatment of inflammation. It has anti-inflammatory and immunosuppressive properties, which are thought to be due to its inhibition of farnesyltransferase. Betamethasone valerate related compound A can be given as an intranasal solution or by injection. The drug substance is a mixture of betamethasone 17-valerate and betamethasone 17,21-dipropionate, which have different kinetic properties. The chemical stability of the drug substance is maintained by using a reaction mechanism involving chromatography.

Formula: C₂₇H₃₇FO₆

Purezza: Min. 95%

Peso molecolare: 476.58 g/mol

Ref: 3D-FB63637