CAS 22465-48-1

Acetato di cobalamina

Descrizione:

Acetato di cobalamina, noto anche come acetato di vitamina B12, è un derivato della cobalamina, essenziale per varie funzioni biologiche nel corpo umano. È caratterizzato dalla sua struttura ad anello corrin contenente cobalto, che è centrale per la sua attività come cofattore nelle reazioni enzimatiche, in particolare nella sintesi del DNA e nella formazione dei globuli rossi. Acetato di cobalamina è tipicamente una polvere cristallina rossa, che riflette il colore caratteristico dei composti di vitamina B12. È solubile in acqua e mostra stabilità in condizioni normali, anche se può essere sensibile alla luce e al calore. Questo composto svolge un ruolo cruciale nel metabolismo degli acidi grassi e degli aminoacidi, e la sua carenza può portare a gravi problemi di salute, tra cui anemia e disturbi neurologici. Acetato di cobalamina è spesso utilizzato in integratori alimentari e alimenti fortificati per prevenire o trattare la carenza di vitamina B12. La sua biodisponibilità e efficacia nel corpo lo rendono un composto importante nella scienza nutrizionale e nella medicina.

Formula: C₆₄H₉₁CoN₁₃O₁₆P

InChI: InChI=1S/C62H90N13O14P.C2H4O2.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2(3)4;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3,(H,3,4);/q;;+3/p-3

InChI key: InChIKey=KPFAAKYTRSSOQN-UHFFFAOYSA-K

SMILES: [O-](C(C)=O)[Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O

Sinonimi:

• Acetatocobalamin
• Co(Acetato-kappaO)cobinamide dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
• Cobalamin, acetato-
• Cobalamin, acetato- (6CI)
• Cobinamide, Co(acetato-kappaO)-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
• Cobinamide, Co-(acetato-κO)-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, acetate phosphate, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole, inner salt
• Depo-gamma
• Fresmin S
• Hydroxocobalamine acetate
• Hydroxycobalamine acetate
• Novidroxin
• Twelvmin
• Unii-S535M27N3Q
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, acetate phosphate, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole, inner salt

Hydroxocobalamin Acetate

CAS: 22465-48-1

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purezza: >90.0%(HPLC)

Colore e forma: Orange to Brown to Dark red powder to crystal

Peso molecolare: 1,388.41

Ref: 3B-H1542

Hydroxocobalamin Acetate

CAS: 22465-48-1

Vitamin b12 (cyanocobalamin and related compounds with vitamin b12 activity) and its derivatives

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Colore e forma: Dark Red Powder

Peso molecolare: 1387.57763

Ref: 45-1324308

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate treats B12 deficiency and cyanide poisoning; FDA-approved with few side effects.

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purezza: 96.73% - 99.86%

Colore e forma: Solid

Peso molecolare: 1388.39

Ref: TM-T13730

Hydroxocobalamin acetate

CAS: 22465-48-1

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purezza: 96.0 - 102.0 %

Colore e forma: Dark red crystalline powder or crystals

Peso molecolare: 1388.39

Ref: 7W-GE5819

Hydroxycobalamine Acetate

CAS: 22465-48-1

Hydroxycobalamine Acetate

Purezza: 98%

Peso molecolare: 1,388.39g/mol

Ref: 54-OR1013546

Hydroxocobalamin Acetate (Vitamin B12 Analog)

CAS: 22465-48-1

Formula: C₆₄H₉₂CoN₁₃O₁₆P

Colore e forma: Dark Red Solid

Peso molecolare: 1389.42

Ref: 4Z-V-035001

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate

Purezza: ≥95%

Peso molecolare: 1388.39g/mol

Ref: 54-BUP14167

Hydroxocobalamin Acetate

CAS: 22465-48-1

Formula: C₆₂H₈₉CoN₁₃O₁₅PC₂H₄O₂

Peso molecolare: 1346.38 : 60.05

Ref: ST-EA-CP-H13001

Hydroxocobalamin Acetate

Prodotto controllato

CAS: 22465-48-1

Applications Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
References Kaczka, E.A., et al.: Science, 112, 354 (1950), Friedrich, W., et al.: Vitamins, 837 (1988), Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993),

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Colore e forma: Dark Red

Peso molecolare: 1388.39

Ref: TR-H826800

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate is a water-soluble form of hydroxocobalamin, a vitamin B12 prodrug. It is an insoluble polymer that dissolves slowly in an acidic environment. Hydroxocobalamin acetate has been shown to inhibit the growth of human carcinoma cells in culture and can be used as a test compound for anticancer drugs. Hydroxocobalamin acetate is also used as a mouth rinse agent to prevent or treat dental cavities. In addition, it can be used to relieve the symptoms of gastroesophageal reflux disease (GERD) by reducing the acidity of gastric contents. This drug has been shown to stimulate vasoactive intestinal polypeptide release from enterochromaffin cells and can be used for the treatment of irritable bowel syndrome (IBS). Hydroxocobalamin acetate is poorly soluble in neutral pH environments and should not be given orally.

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purezza: Min. 90 Area-%

Colore e forma: Red Powder

Peso molecolare: 1,388.39 g/mol

Ref: 3D-FH23894

Cobinamide, Co-(acetato-kO)-, dihydrogen phosphate (ester), innersalt, 3'-ester with(5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3)

CAS: 22465-48-1

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1388.3918

Ref: IN-DA00I4FP