CAS 22494-42-4
:Diflunisal
Descrizione:
Diflunisal è un farmaco antinfiammatorio non steroideo (FANS) che viene utilizzato principalmente per le sue proprietà analgesiche e antinfiammatorie. È caratterizzato dalla sua capacità di inibire l'enzima cicloossigenasi (COX), che gioca un ruolo cruciale nella sintesi delle prostaglandine, composti coinvolti nell'infiammazione e nella segnalazione del dolore. Diflunisal viene tipicamente somministrato sotto forma di compresse ed è noto per la sua emivita relativamente lunga, che consente una somministrazione meno frequente rispetto ad altri FANS. La struttura chimica di Diflunisal include un derivato dell'acido salicilico con due atomi di fluoro, che ne migliora l'efficacia antinfiammatoria. Viene spesso utilizzato nella gestione di condizioni come l'osteoartrite e l'artrite reumatoide. Sebbene generalmente ben tollerato, Diflunisal può causare effetti collaterali tipici dei FANS, tra cui disagio gastrointestinale e potenziali rischi cardiovascolari. Come con qualsiasi farmaco, è essenziale utilizzare Diflunisal sotto supervisione medica per mitigare i rischi e garantire un uso terapeutico appropriato.
Formula:C13H8F2O3
InChI:InChI=1/C13H8F2O3/c14-10-3-1-8(6-11(10)15)7-2-4-12(16)9(5-7)13(17)18/h1-6,16H,(H,17,18)
InChI key:InChIKey=HUPFGZXOMWLGNK-UHFFFAOYSA-N
SMILES:FC1=C(C=CC(F)=C1)C2=CC(C(O)=O)=C(O)C=C2
Sinonimi:- 2',4'-Difluoro-4-Hydroxybiphenyl-3-Carboxylic Acid
- 2-Hydroxy-5-(2,4-difluorophenyl)benzoic acid
- 2′,4′-Difluoro-4-hydroxy[1,1′-biphenyl]-3-carboxylic acid
- 2′,4′-Difluoro-4-hydroxybiphenyl-3-carboxylic acid
- 3-Biphenylcarboxylic acid, 2',4'-difluoro-4-hydroxy-
- 3-Biphenylcarboxylic acid, 2′,4′-difluoro-4-hydroxy-
- 5-(2,4-Difluorophenyl) salicylic acid
- 5-(3,4-Difluorophenyl)-2-Hydroxy-Benzoic Acid
- Adomal
- Difludol
- Diflusinal
- Dolisal
- Doloban
- Dolobid
- Dolobis
- Flovacil
- Fluniget
- Fluodonil
- Flustar
- Mk 647
- [1,1'-Biphenyl]-3-carboxylic acid, 2',4'-difluoro-4-hydroxy-
- [1,1′-Biphenyl]-3-carboxylic acid, 2′,4′-difluoro-4-hydroxy-
- Diflunisal
- 2-(hydroxy)-5-(2,4-difluorophenyl)benzoicacid
- LABOTEST-BB LT00771921
- 1’-biphenyl]-3-carboxylicacid,2’,4’-difluoro-4-hydroxy-[
- 2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid
- 2',4'-DIFLUORO-4-HYDROXY[1,1'-BIPHENYL]-3-CARBOXYLIC ACID
- 2’,4’-difluoro-4-hydroxy-3-biphenylcarboxylicaci
- 1’-biphenyl)-3-carboxylicacid,2’,4’-difluoro-4-hydroxy-(
- 2’,4’-difluoro-4-hydroxy-3-biphenylcarboxylicacid
- 2',4'-DIFLUORO-4-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID
- 2',4'-Difluoro-4-hydroxy-(1',1-diphenyl)-3-carboxylic acid
- Vedi altri sinonimi
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16 prodotti.
Diflunisal
CAS:Formula:C13H8F2O3Purezza:>98.0%(GC)Colore e forma:White to Almost white powder to crystalinePeso molecolare:250.20Diflunisal
CAS:Carboxylic acids with phenol function but without otherFormula:C13H8F2O3Colore e forma:PowderPeso molecolare:250.04415[1,1'-Biphenyl]-3-carboxylic acid, 2',4'-difluoro-4-hydroxy-
CAS:Formula:C13H8F2O3Purezza:98%Colore e forma:SolidPeso molecolare:250.1976Diflunisal
CAS:Diflunisal (Dolobid) is a cyclooxygenase (COX) Inhibitor, used as an anti-inflammatory analgesic.Formula:C13H8F2O3Purezza:98.92% - 99.42%Colore e forma:SolidPeso molecolare:250.20Diflunisal
CAS:Formula:C13H8F2O3Purezza:≥ 98%Colore e forma:White or off-white powderPeso molecolare:250.20Ref: 4Z-D-523
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta2',4'-Difluoro-4-hydroxy[1,1'-biphenyl]-3-carboxylic acid
CAS:2',4'-Difluoro-4-hydroxy[1,1'-biphenyl]-3-carboxylic acidFormula:C13H8F2O3Purezza:98%Colore e forma: pale yellow solidPeso molecolare:250.20g/molRef: ST-EA-CP-D50000
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaDiflunisal
CAS:Prodotto controllato<p>Applications Diflunisal acts as an analgesic agent, used in Alzheimer’s studies (1,2,3) as an anti-inflammatory. As well as in autolytic regulation of human kallikrein -related peptidase 6 (4).<br>References 1. Little, S. et al.: J Biol Chem. 1997 Oct 3;272(40):25135-42.2. Diamandis, E. et al.: Clin. Biochem. 2000 Jul;33(5):369-75.3. Hutchinson, S. et al.: Clin. Chem. 2003 May;49(5):746-51. 4. Baber, S et al.: Biochemistry. 2007 May 1;46(17):5209-17.<br></p>Formula:C13H8F2O3Colore e forma:NeatPeso molecolare:250.20Diflunisal-d3
CAS:Prodotto controllato<p>Applications Labelled Diflunisal. Analgesic; anti-inflammatory.<br>References Little, S., et al.: J. Biol. Chem., 272, 25135 (1997), Diamandis, E., et al.: Clin. Biochem., 33, 369 (2000), Hutchinson, S., et al.: Clin. Chem., 49, 746 (2003), Blaber, S., et al.: Biochemistry, 46, 5209 (2007),<br></p>Formula:C13D3H5F2O3Colore e forma:NeatPeso molecolare:253.216Diflunisal
CAS:<p>Diflunisal is a nonsteroidal anti-inflammatory drug (NSAID), which is a synthetic derivative of salicylic acid. It is primarily sourced through chemical synthesis rather than extraction from natural elements. Diflunisal functions by inhibiting the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which play a crucial role in the biosynthesis of prostaglandins. This inhibition results in reduced production of prostaglandins, compounds involved in inflammation and pain signaling pathways.</p>Formula:C13H8F2O3Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:250.2 g/mol2′,4′-Difluoro-4-hydroxy-biphenyl-3-carboxylic acid
CAS:Formula:C13H8F2O3Purezza:98%Colore e forma:SolidPeso molecolare:250.201
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