CAS 2270986-66-6

CL2 Linker

CAS: 2270986-66-6

CL2 Linker: ADC component, drug load ~6, binds cells (Kd ~1.2 nM), kills (IC50 ~2.2 nM), stable in serum (~20h half-life).

Formula: C₆₈H₁₀₃N₁₁O₂₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1426.61

Ref: TM-T17730

Cl2 linker

CAS: 2270986-66-6

The Cl2 linker is an analog of saxagliptin, a kinase inhibitor that has shown promise in the treatment of tumors and cancer. It has been studied extensively in Chinese hamster ovary cells and human urine, where it has demonstrated potent inhibitory activity against a variety of kinases. The Cl2 linker has also been shown to induce apoptosis in cancer cells, making it a potential therapeutic agent for the treatment of cancer. Additionally, it has been investigated as an inhibitor of xylanase, an enzyme involved in the breakdown of plant cell walls. The Cl2 linker may also have potential as an inhibitor of other kinases, such as those targeted by aprepitant, which is used to treat chemotherapy-induced nausea and vomiting.

Formula: C₆₈H₁₀₃N₁₁O₂₂

Purezza: Min. 95%

Peso molecolare: 1,426.6 g/mol

Ref: 3D-VQD98666