CAS 22818-40-2

D-p-Idrossifenilglicina

Descrizione:

D-p-Idrossifenilglicina, con il numero CAS 22818-40-2, è un derivato di amminoacido caratterizzato dai suoi componenti fenolici e glicina. Presenta un gruppo idrossile (-OH) attaccato alla posizione para dell'anello fenilico, che contribuisce alla sua solubilità e reattività. Questo composto è spesso studiato per le sue potenziali applicazioni in campo farmaceutico, in particolare come mattoncino nella sintesi di varie molecole biologicamente attive. D-p-Idrossifenilglicina mostra chiralità, con specifiche configurazioni stereochimiche che influenzano la sua attività biologica. È tipicamente un solido cristallino bianco a bianco sporco, solubile in acqua e solventi organici, rendendolo versatile per varie reazioni chimiche. La presenza di gruppi funzionali amminici e carbossilici consente di partecipare a reazioni tipiche degli amminoacidi, come la formazione di legami peptidici. Inoltre, le sue caratteristiche strutturali possono consentire interazioni con recettori biologici, rendendolo di interesse in chimica medicinale e progettazione di farmaci. In generale, D-p-Idrossifenilglicina è un composto significativo sia in contesti di chimica sintetica che biologica.

Formula: C₈H₉NO₃

InChI: InChI=1S/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m1/s1

InChI key: InChIKey=LJCWONGJFPCTTL-SSDOTTSWSA-N

SMILES: [C@@H](C(O)=O)(N)C1=CC=C(O)C=C1

Sinonimi:

• (2R)-2-Amino-2-(4-hydroxyphenyl)acetic acid
• (2R)-2-Azaniumyl-2-(4-hydroxyphenyl)acetate
• (2R)-2-amino-2-phenylethanamide
• (2R)-amino(4-hydroxyphenyl)ethanoic acid
• (R)-(-)-alpha-Amino-(4-hydroxyphenyl)acetic acid
• (R)-(4-Hydroxyphenyl)glycine
• (R)-2-(4-Hydroxyphenyl)glycine
• (R)-2-Amino-2-(4-hydroxyphenyl)acetic acid
• (αR)-α-Amino-4-hydroxybenzeneacetic acid
• 2-(4-Hydroxy-phenyl)glycin D-Form
• 4-Hydroxy-<span class="text-smallcaps">D</span>-phenylglycine
• 4-Hydroxy-D-Phenylglycine
• <span class="text-smallcaps">D</span>-(-)-2-(4-Hydroxyphenyl)glycine
• <span class="text-smallcaps">D</span>-(-)-2-(p-Hydroxyphenyl)glycine
• <span class="text-smallcaps">D</span>-(-)-4-Hydroxyphenylglycine
• <span class="text-smallcaps">D</span>-(-)-Amino(4-hydroxyphenyl)acetic acid
• <span class="text-smallcaps">D</span>-(-)-p-Hydroxyphenylglycine
• <span class="text-smallcaps">D</span>-(-)-α-(4-Hydroxyphenyl)glycine
• <span class="text-smallcaps">D</span>-(-)-α-Amino-4-hydroxyphenylacetic acid
• <span class="text-smallcaps">D</span>-(-)-α-Amino-p-hydroxyphenylacetic acid
• <span class="text-smallcaps">D</span>-2-Amino-2-(p-hydroxyphenyl)acetic acid
• <span class="text-smallcaps">D</span>-α-p-Hydroxyphenylglycine
• Benzeneacetic acid, α-amino-4-hydroxy-, (R)-
• Benzeneacetic acid, α-amino-4-hydroxy-, (αR)-
• D(-)-Alpha-Parahydroxy Phenylglycine
• D(-)4-P-hydroxyphenylglycine
• D-(-)-2-(4-Hydroxyphenyl)Glycine
• D-p-hydroxyphenylglycine
• Glycine, 2-(p-hydroxyphenyl)-, <span class="text-smallcaps">D</span>-
• H-D-Phg(4-OH)-OH
• PH Dane-acid
• p-Hydroxy-(R)-phenylglycine
• p-Hydroxy-<span class="text-smallcaps">D</span>-phenylglycine

4-Hydroxy-D-(-)-2-phenylglycine

CAS: 22818-40-2

Formula: C₈H₉NO₃

Purezza: >99.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 167.16

Ref: 3B-H0758

(-)-4-Hydroxy-D-phenylglycine, 98+%

CAS: 22818-40-2

(-)-4-Hydroxy-D-phenylglycine is used as an organic chemical synthesis intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item

Formula: C₈H₉NO₃

Purezza: 98+%

Colore e forma: White to pale cream, Crystals or powder or crystalline powder

Peso molecolare: 167.16

Ref: 02-L07190

Amoxicillin impurity standard

CAS: 188112-75-6, 22818-40-2, 61336-70-7, 94659-47-9

Amoxicillin impurity standard

Colore e forma: White

Ref: 47-748

D-α-(4-hydroxyphenyl)glycine

CAS: 22818-40-2

D-α-(4-hydroxyphenyl)glycine

Colore e forma: White To Off-White

Ref: 47-829

CEFPROZIL IMPURITY A CRS

CAS: 22818-40-2

CEFPROZIL IMPURITY A CRS

Ref: 41-Y0001372

D-α-(4-HYDROXYPHENYL)GLYCINE CRS

CAS: 22818-40-2

D-α-(4-HYDROXYPHENYL)GLYCINE CRS

Ref: 41-H1430000

Amoxicillin Related Compound I ((R)-2-Amino-2-(4-hydroxyphenyl)acetic acid)

CAS: 22818-40-2

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₈H₉NO₃

Colore e forma: White Crystalline Powder

Peso molecolare: 167.16

Ref: 45-1031591

Benzeneacetic acid, a-amino-4-hydroxy-, (aR)-

CAS: 22818-40-2

Formula: C₈H₉NO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 167.1620

Ref: IN-DA007NPA

Amoxicillin EP Impurity I

CAS: 22818-40-2

Formula: C₈H₉NO₃

Colore e forma: White To Off-White Solid

Peso molecolare: 167.16

Ref: 4Z-A-2310

Cefoperazone Impurity 3

CAS: 22818-40-2

Formula: C₈H₉NO₃

Peso molecolare: 167.17

Ref: 4Z-C-7810

4-Hydroxy-D-phenylglycine

CAS: 22818-40-2

4-Hydroxy-D-phenylglycine

Formula: C₈H₉NO₃

Purezza: 98%

Colore e forma: white to off-white powder or crystals or solid

Peso molecolare: 167.16g/mol

Ref: 54-OR8733

4-Hydroxy-D-phenylglycine

CAS: 22818-40-2

Formula: C₈H₉NO₃

Purezza: ≥ 99.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 167.16

Ref: 7W-GM6146

D-α-(4-Hydroxyphenyl-2,3,56-d4)glycine-α-d1

CAS: 22818-40-2

Formula: HOC₆D₄CD(NH₂)COOH

Purezza: 98 atom % D

Peso molecolare: 172.08963

Ref: 3U-D7575

D-4-Hydroxyphenylglycine

CAS: 22818-40-2

D-4-Hydroxyphenylglycine is key in making β-lactam antibiotics like Amoxicillin and Cefadroxil.

Formula: C₈H₉NO₃

Colore e forma: White To Off-White Crystalline Powder

Peso molecolare: 167.16

Ref: TM-T39811

Amoxicillin EP Impurity I (Cefadroxil EP Impurity A)

Prodotto controllato

CAS: 22818-40-2

Formula: C₈H₉NO₃

Colore e forma: Neat

Peso molecolare: 167.16

Ref: 86-MM0232.09

4-Hydroxy-D-(-)-2-phenylglycine

Prodotto controllato

CAS: 22818-40-2

Impurity Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)
Applications 4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)) is an compound used mainly for the synthetic preparation of β-lactam antibiotics.
References Koide, H., et al.: J. Antibio., 65, 91 (2012); Aranaz, I., et al.: Enzyme. Micro. Tech., 39, 215 (2006);

Formula: C₈H₉NO₃

Colore e forma: Neat

Peso molecolare: 167.16

Ref: TR-H949250

Amoxicillin EP Impurity I

CAS: 22818-40-2

Formula: C₈H₉NO₃

Peso molecolare: 167.16

Ref: ST-EA-CP-A20009

Cefadroxil EP Impurity A

CAS: 22818-40-2

Formula: C₈H₉NO₃

Peso molecolare: 167.2

Ref: ST-EA-CP-C61001

p-Hydroxyphenyl glycine HCl

CAS: 22818-40-2

p-Hydroxyphenyl glycine HCl is a model system for an amide and has been shown to inhibit the growth of bacteria. It is also an active analogue of sodium succinate and cyclic peptide, which are glycopeptide antibiotics that have shown activity against gram-positive bacteria such as Streptococcus pneumoniae, Enterococcus faecalis, Staphylococcus aureus, and Bacillus subtilis. The hydroxyl group on p-hydroxyphenyl glycine HCl interacts with hydrogen bonding interactions in the bacterial cell wall, preventing the formation of a covalent bond between the drug molecule and the enzyme cell wall synthesis required for cell wall biosynthesis. This causes inhibition of protein synthesis, leading to cell death by apoptosis.

Formula: C₈H₉NO₃·HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 203.62 g/mol

Ref: 3D-FH01618

(R)-2-Amino-2-(4-hydroxyphenyl)acetic acid

CAS: 22818-40-2

Formula: C₈H₉NO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 167.164

Ref: 10-F222543