CAS 22888-70-6

Silibina

Descrizione:

Silibina, noto anche come silibinina, è un composto flavonoide derivato dalla pianta del cardo mariano (Silybum marianum). È principalmente riconosciuto per le sue proprietà epatoprotettive, rendendolo un integratore popolare per la salute del fegato. Silibina mostra attività antiossidante, che aiuta a neutralizzare i radicali liberi e ridurre lo stress ossidativo nelle cellule. Si sa che il composto migliora l'attività di alcuni enzimi epatici e promuove la rigenerazione del tessuto epatico. Inoltre, Silibina è stato studiato per i suoi potenziali effetti anti-infiammatori e anticancro, poiché può inibire la crescita di varie linee cellulari tumorali. È generalmente disponibile sotto forma di silimarina, un complesso di flavonolignani che include Silibina come suo principale componente attivo. Silibina ha bassa solubilità in acqua, il che può influenzare la sua biodisponibilità; tuttavia, sono state sviluppate varie formulazioni, inclusi complessi di fosfolipidi, per migliorare la sua assorbimento nel corpo. In generale, Silibina è apprezzato per il suo potenziale terapeutico, in particolare nel contesto dei disturbi epatici e della salute generale.

Formula: C₂₅H₂₂O₁₀

InChI: InChI=1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23+,24-,25-/m1/s1

InChI key: InChIKey=SEBFKMXJBCUCAI-HKTJVKLFSA-N

SMILES: C(O)[C@@H]1[C@H](OC=2C(O1)=CC=C(C2)[C@H]3OC=4C(C(=O)[C@@H]3O)=C(O)C=C(O)C4)C5=CC(OC)=C(O)C=C5

Sinonimi:

• (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one
• (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one
• (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one
• 1,4-Benzodioxin, 4H-1-benzopyran-4-one deriv.
• 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin
• 4-Chromanone, 3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl]-
• 4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-
• 4H-1-Benzopyran-4-one, 2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, [2R-[2α,3β,6(2R*,3R*)]]-
• 7C3Mt
• Mepasil
• Milk Thistel P.E.
• Milk Thistle Extract
• Realsil
• Silibinin
• Silibinin A
• Silliver
• Silybin
• Silybin A
• Silybin b₁
• Silybine
• Silybum Extract
• Silybum marianum
• Silybum substance E₆
• Silymarin Group
• Silymarin I
• Silymarin MZ 80

Silybin (mixture of Silybin A and Silybin B)

CAS: 142797-34-0, 22888-70-6, 36804-17-8

Formula: C₂₅H₂₂O₁₀

Purezza: >98.0%(HPLC)

Colore e forma: White to Orange to Green powder to crystaline

Peso molecolare: 482.44

Ref: 3B-S0508

Silybin (Mixture of Silybin A and B)

CAS: 22888-70-6

Colore e forma: Mixture

Ref: 61-FOR0472.00

Silybin

CAS: 22888-70-6

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₂₅H₂₂O₁₀

Colore e forma: Off-White Powder

Peso molecolare: 482.1213

Ref: 45-1612630

Silybin (Mixture of Silybin A and B)

CAS: 142797-34-0, 22888-70-6

Formula: C₂₅H₂₂O₁₀

Peso molecolare: 482.44

Ref: 04-MM0472.00

(2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-3,4-dihydro-2H-1-benzopyran-4-one

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 482.4362

Ref: IN-DA00I4I7

Silybin

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White, off-white or yellow powder

Peso molecolare: 482.44

Ref: 7W-GP4040

Silibinin

CAS: 22888-70-6

Silibinin

Purezza: ≥95%

Peso molecolare: 482.44g/mol

Ref: 54-BUP16622

Silybin (Mixture of Silybin A and B)

Prodotto controllato

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Colore e forma: Mixture

Peso molecolare: 482.44

Ref: 86-MM0472.00

Silybin A

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Purezza: 95%~99%

Peso molecolare: 482.441

Ref: BP-BP5185

Silybin A

CAS: 22888-70-6

Silybin A

Formula: C₂₅H₂₂O₁₀

Purezza: 98%

Colore e forma: pale yellow solid

Peso molecolare: 482.44g/mol

Ref: 54-BIC1034

Silybin A-d3

CAS: 22888-70-6

Formula: C₂₅H₁₉O₁₀D₃

Peso molecolare: 485.47

Ref: 4Z-S-394

Silybin A

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Colore e forma: Off-White Solid

Peso molecolare: 482.45

Ref: 4Z-S-391

Silibinin

CAS: 22888-70-6

Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.

Formula: C₂₅H₂₂O₁₀

Purezza: 97.98% - 98.37%

Colore e forma: Solid

Peso molecolare: 482.44

Ref: TM-T1660

Silybin a

CAS: 22888-70-6

Oxygen-heterocyclic compound

Formula: C₂₅H₂₂O₁₀

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 482.44

Ref: 5G-82653

Silybin A

Prodotto controllato

CAS: 22888-70-6

Applications Silybin A is the 2R, 3R, 7‘R, 8‘R isomer of Silybin (S465850); a natural occurring flavolignan that exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells.
References Lee, D.Y.W, et al.: J. Nat. Prod., 66, 1171 (2003); Trappoliere, M., et al.: J. Hepatol., 50, 1102 (2009); Borsari, M., et al.: J. Inorg. Biochem., 85, 123 (2001)

Formula: C₂₅H₂₂O₁₀

Colore e forma: Neat

Peso molecolare: 482.44

Ref: TR-S465855

Silybin

CAS: 22888-70-6

Silybin is a bioactive compound, which is a flavonolignan, derived from the seeds of the Silybum marianum plant, commonly known as milk thistle. This compound is primarily obtained through solvent extraction and purification processes from the dried seeds of the plant.

Formula: C₂₅H₂₂O₁₀

Purezza: Min. 97 Area-%

Colore e forma: Powder

Peso molecolare: 482.44 g/mol

Ref: 3D-FS02332

(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one

CAS: 22888-70-6

Purezza: 95%

Peso molecolare: 482.4410095

Ref: 10-F870214