CAS 23094-69-1

Corilagina

Descrizione:

Corilagina è un composto polifenolico che si trova naturalmente, classificato come un tannino, presente principalmente in varie piante, in particolare nella famiglia delle Phyllanthaceae. È noto per le sue proprietà antiossidanti, antinfiammatorie e antimicrobiche, rendendolo di interesse sia nella ricerca farmacologica che nutrizionale. Corilagina presenta una struttura complessa, caratterizzata da più gruppi idrossilici che contribuiscono alla sua reattività e attività biologica. Il composto è stato studiato per i suoi potenziali effetti terapeutici, incluso il suo ruolo nella modulazione delle vie metaboliche e i suoi effetti protettivi contro lo stress ossidativo. Inoltre, Corilagina ha mostrato promesse in vari studi in vitro e in vivo per la sua capacità di influenzare le vie di segnalazione cellulare, il che potrebbe avere implicazioni per il trattamento di malattie come il cancro e il diabete. La sua solubilità in acqua e solventi organici varia, il che può influenzare la sua biodisponibilità e efficacia in diverse applicazioni. In generale, Corilagina rappresenta un'area significativa di interesse nella chimica dei prodotti naturali e nella farmacologia grazie alle sue diverse attività biologiche.

Formula: C₂₇H₂₂O₁₈

InChI: InChI=1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)23-19(35)13(43-27)5-42-25(40)7-3-11(30)17(33)20(36)14(7)15-8(26(41)44-23)4-12(31)18(34)21(15)37/h1-4,13,19,22-23,27-38H,5H2

InChI key: InChIKey=TUSDEZXZIZRFGC-UHFFFAOYSA-N

SMILES: OC1=C2C=3C(=CC(O)=C(O)C3O)C(=O)OCC4C(O)C(OC(=O)C2=CC(O)=C1O)C(O)C(OC(=O)C5=CC(O)=C(O)C(O)=C5)O4

Sinonimi:

• (8R,10S,11R,12S,19R)-1,2,3,11,16,17,18,19-octahydroxy-5,14-dioxo-5,7,8,11,12,14-hexahydro-10H-8,12-methanodibenzo[j,l][1,4,8]trioxacyclotetradecin-10-yl 3,4,5-trihydroxybenzoate
• 1,2,3,11,16,17,18,19-octahydroxy-5,14-dioxo-5,7,8,11,12,14-hexahydro-10H-8,12-methanodibenzo[j,l][1,4,8]trioxacyclotetradecin-10-yl 3,4,5-trihydroxybenzoate
• 8,12-Methano-10H-dibenzo[j,l][1,4,8]trioxacyclotetradecin, β-<span class="text-smallcaps">D</span>-glucopyranose deriv.
• Corillagin
• Glucopyranose, cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxydiphenate) 1-gallate, β-<span class="text-smallcaps">D</span>-
• beta-D-Glucopyranose, cyclic 3,6-(4,4',5,5',6,6'-hexahydroxy(1,1'-biphenyl)-2,2'-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), (R)-
• β-<span class="text-smallcaps">D</span>-Glucopyranose, cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), (R)-
• β-<span class="text-smallcaps">D</span>-Glucopyranose, cyclic 3,6-[(1R)-4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate] 1-(3,4,5-trihydroxybenzoate)
• β-D-Glucopyranose, cyclic 3,6-[(1R)-4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate] 1-(3,4,5-trihydroxybenzoate)
• 8,12-Methano-10H-dibenzo[j,l][1,4,8]trioxacyclotetradecin, β-D-glucopyranose deriv.
• β-D-Glucopyranose, cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), (R)-
• Glucopyranose, cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxydiphenate) 1-gallate, β-D-

β-D-Glucopyranose, cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1-(3,4,5-trihydroxybenzoate)

CAS: 23094-69-1

Formula: C₂₇H₂₂O₁₈

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 634.4528

Ref: IN-DA002M6S

Corilagin

CAS: 23094-69-1

Corilagin

Purezza: ≥98%

Peso molecolare: 634.45g/mol

Ref: 54-BUP06428

Corilagin

CAS: 23094-69-1

Corilagin

Purezza: 98%

Peso molecolare: 634.45g/mol

Ref: 54-OR1024248

Corilagin

CAS: 23094-69-1

Corilagin has antitumour, anti-inflammatory, antioxidant, antifibrotics, antiviral, antibacterial, hepatoprotective, antiatherogenic, and antihypertensive activities. Corilagin reduces the cytotoxicity induced by EV71 or CA16 on Vero cells with and IC50 value of 5.6 and 32.33 μg/mL, respectively; it shows the potential to protect against HSV-1-induced encephalitis, and the beneficial effects may be mediated by inhibiting TLR2 signaling pathways. Corilagin attenuates bleomycin-induced epithelial injury and fibrosis via inactivation of oxidative stress, proinflammatory cytokine release and NF-κB and TGF-β1 signaling; it suppresses the activity of beta-lactamase to some extent.

Formula: C₂₇H₂₂O₁₈

Purezza: 95%~99%

Peso molecolare: 634.455

Ref: BP-BP0393

Corilagin

CAS: 23094-69-1

Formula: C₂₇H₂₂O₁₈

Peso molecolare: 634.46

Ref: 4Z-C-495001

Corilagin

CAS: 23094-69-1

Corilagin has anti-inflammatory activity.

Formula: C₂₇H₂₂O₁₈

Purezza: 99.54% - 99.95%

Colore e forma: Off-White Solid

Peso molecolare: 634.45

Ref: TM-T3795

Corilagin

CAS: 23094-69-1

Formula: C₂₇H₂₂O₁₈

Purezza: ≥ 98.0%

Colore e forma: White to off-white, light yellow or light brown powder

Peso molecolare: 634.46

Ref: 7W-GC8106

Corilagin

CAS: 23094-69-1

Natural glycoside

Formula: C₂₇H₂₂O₁₈

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 634.46

Ref: 5G-80390

Corilagin

Prodotto controllato

CAS: 23094-69-1

Stability Hygroscopic
Applications Thrombolytic.
References Shen, Z-Q., et al.: Planta Med., 69, 1109 (2003),

Formula: C₂₇H₂₂O₁₈

Colore e forma: Neat

Peso molecolare: 634.45

Ref: TR-C695400

Corilagin

Prodotto controllato

CAS: 23094-69-1

Corilagin is a natural compound that has been shown to inhibit cancer cell growth and induce apoptosis. Corilagin inhibits the production of anion radicals, which are reactive species that contribute to oxidative stress and inflammation. Corilagin also has an anti-inflammatory effect by inhibiting the production of pro-inflammatory cytokines. In addition, corilagin induces autophagy, a process where cells degrade their own components through the lysosomal machinery in order to generate energy and eliminate toxic substances. Corilagin is also able to reduce cellular transformation through its ability to inhibit secretase activity.

Formula: C₂₇H₂₂O₁₈

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 634.45 g/mol

Ref: 3D-MC11453