CAS 23210-56-2

Ifenprodil

Descrizione:

Ifenprodil è un composto chimico riconosciuto principalmente per il suo ruolo come agente neuroprotettivo e per le sue potenziali applicazioni terapeutiche nel trattamento dei disturbi neurologici. È classificato come un antagonista non competitivo del recettore NMDA (N-metil-D-aspartato), che svolge un ruolo cruciale nella plasticità sinaptica e nella funzione della memoria. Ifenprodil mostra selettività per alcuni sottotipi di recettori NMDA, in particolare quelli contenenti la subunità NR2B, rendendolo di interesse nella ricerca relativa alle malattie neurodegenerative e alle condizioni associate all'eccitotossicità. Il composto viene tipicamente somministrato nella sua forma di sale cloridrico ed è noto per la sua capacità di modulare la neurotrasmissione glutamatergica. Inoltre, Ifenprodil è stato studiato per i suoi potenziali effetti sulla salute cardiovascolare, poiché potrebbe influenzare la funzione della muscolatura liscia vascolare. La sua farmacocinetica, che include assorbimento, distribuzione, metabolismo ed escrezione, è importante per comprendere la sua efficacia e il profilo di sicurezza in contesti clinici. In generale, Ifenprodil rappresenta un'area significativa di interesse nella ricerca farmacologica, in particolare nel contesto della neuroprotezione e delle strategie terapeutiche correlate.

Formula: C₂₁H₂₇NO₂

InChI: InChI=1/2C21H27NO2.C4H6O6/c2*1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17;5-1(3(7)8)2(6)4(9)10/h2*2-10,16,18,21,23-24H,11-15H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)

InChI key: InChIKey=UYNVMODNBIQBMV-UHFFFAOYSA-N

SMILES: C(C1CCN(C(C(O)C2=CC=C(O)C=C2)C)CC1)C3=CC=CC=C3

Sinonimi:

• 1-Methyl-2-hydroxy-2-(4-hydroxyphenyl)ethyl-1-(4-benzylpiperidine)
• 1-Piperidineethanol, 4-benzyl-α-(p-hydroxyphenyl)-β-methyl-
• 1-Piperidineethanol, Alpha-(4-Hydroxyphenyl)-Beta-Methyl-4-(Phenylmethyl)-
• 1-Piperidineethanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-
• 2-(4-Benzylpiperidino)-1-(1-hydroxyphenyl)-1-propanol
• 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol
• 23210-56-2
• 4-Benzyl-a-(p-hydroxyphenyl)-b-methyl-1-piperidineethanol
• 4-[2-(4-Benzyl-1-pipéridinyl)-1-hydroxypropyl]phénol
• 4-[2-(4-Benzylpiperidin-1-Yl)-1-Hydroxypropyl]Phenol 2,3-Dihydroxybutanedioate (2:1)
• 4-[2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl]phenol
• 66157-43-5
• Rc 61-91
• α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidineethanol
• Ifenprodil
• (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate
• (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanolhemitartrate
• 4-benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethano
• 1-(4-Hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol
• alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidineethano
• 4-[2-[4-(benzyl)-1-piperidyl]-1-hydroxy-propyl]phenol
• 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol tartrate (2:1) salt
• alpha-(4-Hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidineethanol
• 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)propanol
• 4-[1-Hydroxy-2-[4-(phenylmethyl)piperidin-1-yl]propyl]phenol
• 4-benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethanol
• 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)propan-1-ol

Ifenprodil hemitartrate, 99%

CAS: 23210-56-2

NMDA receptor antagonist, acting at the polyamine site

Formula: C₂₁H₂₇NO₂·5C₄H₆O₆

Purezza: 99%

Peso molecolare: 400.49

Ref: 02-J60932

Ifenprodil

CAS: 23210-56-2

Ifenprodil (RC61-91) inhibits NMDA receptor subunits GluN1 & GluN2B, GIRK channels, and affects alpha1, serotonin, sigma receptors.

Formula: C₂₁H₂₇NO₂

Purezza: 99.58%

Colore e forma: White Crystalline Powder

Peso molecolare: 325.44

Ref: TM-T1186L

1-Piperidineethanol, α-(4-hydroxyphenyl)-β-methyl-4-(phenylmethyl)-

CAS: 23210-56-2

Formula: C₂₁H₂₇NO₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 325.44458

Ref: IN-DA002MJD

Ifenprodil

CAS: 23210-56-2

Ifenprodil

Purezza: ≥98%

Peso molecolare: 325.44g/mol

Ref: 54-BUP09455

Ifenprodil

CAS: 23210-56-2

Formula: C₂₁H₂₇NO₂₀·5C₄H₆O₆

Peso molecolare: 400.49

Ref: 7W-GP2257

Ifenprodil

Prodotto controllato

CAS: 23210-56-2

Applications Ifenprodil is a NMDA receptor antagonist.
References Berger, et al.: J. Pharmacol. Exp. Ther., 289, 1584 (1999);

Formula: C₂₁H₂₇NO₂

Colore e forma: Neat

Peso molecolare: 325.44

Ref: TR-I258003

Ifenprodil

Prodotto controllato

CAS: 23210-56-2

Ifenprodil is a selective NMDA (N-Methyl-D-aspartate) receptor antagonist, which is a synthetic compound designed to modulate glutamatergic neurotransmission. It is derived from a class of organic compounds known as phenylethanolamines. Its primary mode of action involves the inhibition of NMDA receptors containing the GluN2B subunit, which leads to a reduction in excitatory neurotransmission. This specific antagonism is crucial for modulating synaptic plasticity and protecting neural tissue from excitotoxic damage.

Formula: (C₂₁H₂₇NO₂)·C₄H₆O₆

Purezza: Min. 95%

Peso molecolare: 800.98 g/mol

Ref: 3D-YAA21058