CAS 2361-96-8

Etil estere di acetil-L-fenilalanina

Descrizione:

Etil estere di acetil-L-fenilalanina, con il numero CAS 2361-96-8, è un derivato estere dell'aminoacido fenilalanina. Questo composto presenta un gruppo acetile attaccato al gruppo amminico della fenilalanina, insieme a un gruppo estere etilico all'estremità dell'acido carbossilico. Tipicamente è un solido cristallino bianco a bianco sporco, solubile in solventi organici come etanolo e metanolo, ma meno solubile in acqua. La presenza del gruppo acetile ne migliora la lipofilia, il che può influenzare la sua attività biologica e le caratteristiche di assorbimento. Etil estere di acetil-L-fenilalanina è spesso studiato nel contesto della sintesi peptidica e come potenziale intermedio nella produzione di farmaci. Le sue caratteristiche strutturali gli consentono di partecipare a varie reazioni chimiche, rendendolo un composto prezioso nella sintesi organica e nella chimica medicinale. Inoltre, a causa della sua natura di aminoacido, potrebbe presentare alcune attività biologiche, sebbene le applicazioni specifiche possano variare in base alla ricerca e allo sviluppo in corso.

Formula: C₁₃H₁₇NO₃

InChI: InChI=1S/C13H17NO3/c1-3-17-13(16)12(14-10(2)15)9-11-7-5-4-6-8-11/h4-8,12H,3,9H2,1-2H3,(H,14,15)/t12-/m0/s1

InChI key: InChIKey=YIVZYFDBEPMPNL-LBPRGKRZSA-N

SMILES: [C@H](CC1=CC=CC=C1)(C(OCC)=O)NC(C)=O

Sinonimi:

• <span class="text-smallcaps">L</span>-N-Acetylphenylalanine ethyl ester
• <span class="text-smallcaps">L</span>-Phenylalanine, N-acetyl-, ethyl ester
• Ac-Phe-OEt
• Acetyl-<span class="text-smallcaps">L</span>-phenylalanine ethyl ester
• Acetylphenylalanine ethyl ester
• Alanine, N-acetyl-3-phenyl-, ethyl ester, <span class="text-smallcaps">L</span>-
• Ethyl N-acetyl-<span class="text-smallcaps">L</span>-phenylalaninate
• N-Acetyl-<span class="text-smallcaps">L</span>-phenylalanine ethyl ester
• N-Acetylphenylalanine ethyl ester
• ethyl N-acetyl-3-phenyl-L-alaninate
• ethyl N-acetyl-L-phenylalaninate
• ethyl N-acetylphenylalaninate
• L-Phenylalanine, N-acetyl-, ethyl ester
• N-Acetyl-L-phenylalanine ethyl ester
• Acetyl-L-phenylalanine ethyl ester

(S)-Ethyl 2-acetamido-3-phenylpropanoate

CAS: 2361-96-8

Formula: C₁₃H₁₇NO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 235.2790

Ref: IN-DA003SP2

N-Acetyl-L-Phenylalanine Ethyl Ester

CAS: 2361-96-8

N-Acetyl-L-Phenylalanine Ethyl Ester

Purezza: 98%

Peso molecolare: 235.28g/mol

Ref: 54-OR1014236

Ac-Phe-OEt

CAS: 2361-96-8

Formula: C₁₃H₁₇NO₃

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 235.28

Ref: 3B-A3498

Ac-Thz-Tle-Leu-Gln-MCA

CAS: 2361-96-8

A prototype fluorogenic substrate targeting the SARS-CoV and SARS-CoV-2 Main Protease (Mpro). The main protease (Mpro­), also called endopeptidase C30 or 3C-like proteinase (3CLpro), controls viral replication activities and is a prime therapeutical target. Both substrates and inhibitors of SARS-CoV-2 Mpro are currently of interest to researchers of the coronavirus. This product can be used as a Prototype Fluorescence Substrate for SARS-CoV Mpro/SARS-CoV-2 Mpro Proteases.

Formula: C₁₃H₁₇NO₃

Purezza: Min. 95%

Peso molecolare: 235.28 g/mol

Ref: 3D-SFP-3251-V

Acetyl-L-phenylalanine Ethyl Ester

Prodotto controllato

CAS: 2361-96-8

Applications Acetyl-L-phenylalanine ethyl ester is a derivative of L-Phenylalanine (P319415), a nonpolar, essential amino acid that naturally occurs in the human body and is also used to treat patients with depression. Acetyl-L-phenylalanine ethyl ester is also used to inhibit pepsin-catalyzed reactions.
References Auer, H. & Doty, P.: Biochemistry, 5, 1708 (1966); Birkmayer, W., et al.: J. Neural Transm., 59, 81 (1984); Borison, R., et al.: Res. Commun. Chem. Path., 21, 363 (1978); Kitson, T., et al.: Biochem. J., 122, 241 (1971)

Formula: C₁₃H₁₇NO₃

Colore e forma: Neat

Peso molecolare: 235.28

Ref: TR-A187950

(S)-Ethyl 2-acetamido-3-phenylpropanoate

CAS: 2361-96-8

Formula: C₁₃H₁₇NO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 235.283

Ref: 10-F224477

Acetyl-L-phenylalanine ethyl ester

CAS: 2361-96-8

Acetyl-L-phenylalanine ethyl ester is a substrate analogue that competes with the natural substrate, L-phenylalanine, for binding sites on the enzyme. The acetyl group of acetyl-L-phenylalanine ethyl ester reacts with the amino acid residues of L-phenylalanine to form covalent linkages. This prevents the enzyme from catalyzing reactions involving L-phenylalanine and other substrates. Acetyl-L-phenylalanine ethyl ester binds to cytochalasin B and inhibits its ability to bind to actin filaments, thus inhibiting cell growth. The high salt concentration in this experiment allows for separation of the protein from other cellular components by sephadex g-100 chromatography. Kinetic studies have been done on human serum albumin, which is a protein that can bind acetyl-L-phenylalanine ethl ester with a

Formula: C₁₃H₁₇NO₃

Purezza: Min. 95%

Peso molecolare: 235.28 g/mol

Ref: 3D-FA47441

Ac-Phe-OEt

CAS: 2361-96-8

Ac-Phe-OEt is a covalently conjugated bifunctional peptide that has been synthesized by linking the amino acid phenylalanine to the amino acid ethyl ester of oleic acid. Ac-Phe-OEt exhibits a high affinity for bacterial serine proteases (Km=0.1 μM) and lysine residues (Ki=4 μM). This peptide also binds to immobilized cytochalasin, which prevents the formation of amyloid fibrils. Ac-Phe-OEt can be used in enzyme catalysis as an inhibitor or competitive inhibitor, as well as being immobilized on surfaces. The kinetic data suggests that Ac-Phe-OEt competes with lysine residues for binding to bacterial serine proteases and inhibits their activity.

Formula: C₁₃H₁₇NO₃

Purezza: Min. 95%

Peso molecolare: 235.28 g/mol

Ref: 3D-SFE-3006