CAS 23642-66-2

Cloridrato di benfluorex

Descrizione:

Cloridrato di benfluorex è un composto sintetico utilizzato principalmente come farmaco anti-obesità ed è stato associato al trattamento dei disturbi metabolici. È un derivato della fenfluramina e agisce come un agonista del recettore della serotonina, influenzando la regolazione dell'appetito e il dispendio energetico. La sostanza è tipicamente presentata come una polvere cristallina bianca o bianco sporco, solubile in acqua e con un profilo di stabilità moderato in condizioni standard. La sua struttura chimica include un anello fenilico fluorurato, che contribuisce alle sue proprietà farmacologiche. Cloridrato di benfluorex è stato notato per i suoi potenziali effetti collaterali, inclusi problemi cardiovascolari, che hanno portato al suo ritiro da diversi mercati. Come molti farmaci, il suo uso richiede una attenta considerazione del dosaggio e dello stato di salute del paziente, ed è soggetto a scrutinio normativo. In generale, sebbene abbia applicazioni terapeutiche, il profilo di sicurezza e lo stato normativo di Cloridrato di benfluorex richiedono un uso cauto e una valutazione continua in contesti clinici.

Formula: C₁₉H₂₀F₃NO₂·ClH

InChI: InChI=1S/C19H20F3NO2.ClH/c1-14(12-15-6-5-9-17(13-15)19(20,21)22)23-10-11-25-18(24)16-7-3-2-4-8-16;/h2-9,13-14,23H,10-12H2,1H3;1H

InChI key: InChIKey=NLOALSPYZIIXEO-UHFFFAOYSA-N

SMILES: C(C(NCCOC(=O)C1=CC=CC=C1)C)C2=CC(C(F)(F)F)=CC=C2.Cl

Sinonimi:

• (±)-N-(2-Benzoyloxyethyl)norfenfluramine hydrochloride
• 2-((1-Methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)ethyl benzoate hydrochloride
• 2-((alpha-Methyl-m-(trifluoromethyl)phenethyl)amino)ethanol benzoate (ester)
• 2-(-Methyl-3-(trifluoromethyl)phenethylamino)ethyl benzoate hydrochloride
• 2-(alpha-Methyl-3-(trifluoromethyl)phenylethylamino)ethyl benzoat
• 2-({1-[3-(Trifluoromethyl)Phenyl]Propan-2-Yl}Amino)Ethyl Benzoate Hydrochloride (1:1)
• Balans
• Benfluorex HCl
• Ethanol, 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-, benzoate (ester), hydrochloride
• Ethanol, 2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-, benzoate (ester), HCl
• Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, 1-benzoate, hydrochloride (1:1)
• Ethanol, 2-[[α-methyl-m-(trifluoromethyl)phenethyl]amino]-, benzoate (ester), hydrochloride
• Jp 992
• Lipophoral
• Mediator
• Mediaxal
• S 992
• Unii-X7O165Xz00
• Benfluorex hydrochloride

2-((1-(3-(Trifluoromethyl)phenyl)propan-2-yl)amino)ethyl benzoate hydrochloride

CAS: 23642-66-2

Formula: C₁₉H₂₁ClF₃NO₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 387.8237

Ref: IN-DA002O0S

2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethyl benzoate hydrochloride

CAS: 23642-66-2

2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethyl benzoate hydrochloride

Purezza: ≥95%

Peso molecolare: 387.82g/mol

Ref: 54-PC8120

Benfluorex hydrochloride

Prodotto controllato

CAS: 23642-66-2

Formula: C₁₉H₂₁ClF₃NO₂

Colore e forma: Neat

Peso molecolare: 387.82

Ref: 04-C10469000

Benfluorex Hydrochloride

Prodotto controllato

CAS: 23642-66-2

Applications Used as an antihyperlipoproteinemic therapeutic.
References Beckett, A.H., et al.: J. Pharm. Pharmacol., 23, 950 (1971), Brindley, D.N., et al.: J. Pharm. Pharmacol., 28, 670 (1976)

Formula: C₁₉H₂₁ClF₃NO₂

Colore e forma: White Solid

Peso molecolare: 387.82

Ref: TR-B135000

Benfluorex hydrochloride

Prodotto controllato

CAS: 23642-66-2

Benfluorex hydrochloride is a fluorinated derivative of benfluorex, which is an experimental drug for the treatment of bone cancer. It was shown to be effective in treating bowel disease, primary pulmonary hypertension and carcinoid syndrome in animal models. Benfluorex hydrochloride inhibits the activity of enzymes that are involved in the metabolism of carbohydrates and lipids. It has been shown to increase uric acid levels and inhibit the activity of enzymes that are involved in the synthesis of amino acids. This leads to cell lysis and an increased production of glucose-6-phosphate. The use of benfluorex hydrochloride as a diagnostic tool has been studied extensively, with its most notable application being its use as a marker for group P2 enzyme activities.

Formula: C₁₉H₂₀F₃NO₂•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 387.82 g/mol

Ref: 3D-FB103383