CAS 23651-95-8
:Droxidopa
Descrizione:
Droxidopa, con il numero CAS 23651-95-8, è un analogo sintetico dell'aminoacido della norepinefrina, utilizzato principalmente come farmaco per trattare l'ipotensione ortostatica neurogena. Funziona come un pro-farmaco, convertendosi in norepinefrina nel corpo, il che aiuta ad aumentare la pressione sanguigna e migliorare il flusso sanguigno. La formula chimica di Droxidopa è C9H11NO4 e ha un peso molecolare di circa 197,19 g/mol. Questo composto è caratterizzato dalla sua capacità di attraversare la barriera ematoencefalica, rendendolo efficace nel trattamento di condizioni associate a bassa pressione sanguigna a causa di disfunzione autonoma. Droxidopa è tipicamente somministrato per via orale ed è noto per il suo profilo di sicurezza relativamente favorevole, sebbene possa causare effetti collaterali come mal di testa, nausea e ipertensione. La sua farmacocinetica implica un rapido assorbimento e metabolismo, con concentrazioni plasmatiche massime che si verificano entro poche ore dopo la somministrazione. In generale, Droxidopa rappresenta un'opzione terapeutica significativa per i pazienti che soffrono di forme specifiche di ipotensione ortostatica.
Formula:C9H11NO5
InChI:InChI=1S/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8+/m0/s1
InChI key:InChIKey=QXWYKJLNLSIPIN-JGVFFNPUSA-N
SMILES:[C@@H]([C@@H](C(O)=O)N)(O)C1=CC(O)=C(O)C=C1
Sinonimi:- (-)-threo-3,4-Dihydroxyphenylserine
- (2S,3R)-3-(3,4-Dihydroxyphenyl)-2-amino-3-hydroxypropanoic acid
- (2S,3S)-2-ammonio-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate
- (betaS)-beta,3-dihydroxy-D-tyrosine
- (βR)-β,3-Dihydroxy-<span class="text-smallcaps">L</span>-tyrosine
- <span class="text-smallcaps">L</span>-DOPS
- <span class="text-smallcaps">L</span>-Threodops
- <span class="text-smallcaps">L</span>-Tyrosine, β,3-dihydroxy-, (βR)-
- <span class="text-smallcaps">L</span>-Tyrosine, β,3-dihydroxy-, threo-
- <span class="text-smallcaps">L</span>-threo-3,4-Dihydroxyphenylserine
- <span class="text-smallcaps">L</span>-threo-3-(3,4-Dihydroxyphenyl)serine
- <span class="text-smallcaps">L</span>-threo-DOPS
- <span class="text-smallcaps">L</span>-threo-β-(3,4-Dihydroxyphenyl)serine
- Northera
- Serine, 3-(3,4-dihydroxyphenyl)-
- Serine, 3-(3,4-dihydroxyphenyl)-, <span class="text-smallcaps">L</span>-threo-
- Sm 5688
- Tyrosine, Beta,3-Dihydroxy-
- beta,3-Dihydroxytyrosine
- threo-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic acid
- threo-3-(3,4-Dihydroxyphenyl)-<span class="text-smallcaps">L</span>-serine
- threo-Dopaserine
- Serine, 3-(3,4-dihydroxyphenyl)-, L-threo-
- L-Tyrosine, β,3-dihydroxy-, (βR)-
- (βR)-β,3-Dihydroxy-L-tyrosine
- L-threo-3,4-Dihydroxyphenylserine
- Vedi altri sinonimi
Ordinare per
Purezza (%)
0
100
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0
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50
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90
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95
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100
11 prodotti.
Droxidopa
CAS:Formula:C9H11NO5Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:213.19Droxidopa
CAS:Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormula:C9H11NO5Colore e forma:White Pale Yellow PowderPeso molecolare:213.06372L-Tyrosine, β,3-dihydroxy-, (βR)-
CAS:Formula:C9H11NO5Purezza:98%Colore e forma:SolidPeso molecolare:213.1873Droxidopa
CAS:Droxidopa (L-DOPS), an oral prodrug, treats symptomatic orthostatic hypotension from neurogenic autonomic failure.Formula:C9H11NO5Purezza:97.27% - 99.88%Colore e forma:SolidPeso molecolare:213.19L-threo-Droxidopa-13C6
CAS:Prodotto controllatoFormula:C3C6H11NO5Colore e forma:NeatPeso molecolare:216.119L-threo-droxidopa
CAS:<p>L-threo-droxidopa is a prodrug that is hydrolyzed in the liver to L-3,4-dihydroxyphenylalanine (L-DOPA) and then metabolized by dopamine β-hydroxylase to form dopamine. This drug has been shown to be effective for the treatment of Parkinson's disease. The long-term efficacy of this drug is unknown, but it has been shown to be safe and well tolerated for up to six months. L-threo-droxidopa has also been shown to be effective in lowering systolic blood pressure in patients with mild hypertension. The side effects of this drug include symptoms such as nausea, vomiting, dizziness, headache, and insomnia. However, these side effects are often transient and do not require discontinuation of treatment with this medication. There are no known interactions between L-threo-droxidopa and other drugs or foods. Pharmacological</p>Formula:C9H11NO5Purezza:Min. 95%Colore e forma:Off-White To Light (Or Pale) Beige SolidPeso molecolare:213.19 g/mol
