CAS 2375482-51-0

BI-2852

CAS: 2375482-51-0

Formula: C₃₁H₂₈N₆O₂

Purezza: 95%

Peso molecolare: 516.5930

Ref: IN-DA01K4U9

BI-2852

CAS: 2375482-51-0

BI-2852

Purezza: ≥98%

Peso molecolare: 516.59g/mol

Ref: 54-BUP06969

BI-2852

CAS: 2375482-51-0

BI-2852 is a drug binding inhibitor that is selective for the protein kinases of the Src family and inhibits the phosphorylation of tyrosine residues on these proteins. BI-2852 binds to and blocks the ATP-binding site on these enzymes, preventing their activation. This compound was shown to inhibit cancer cell growth in vitro and in vivo, by inducing cell cycle arrest and apoptosis. BI-2852 has been shown to be an allosteric inhibitor, activating the enzyme at lower concentrations than those required for the classical inhibitors. It also inhibits protein synthesis by binding to and inhibiting ribosomes in bacteria.

Formula: C₃₁H₂₈N₆O₂

Purezza: Min. 95%

Peso molecolare: 516.6 g/mol

Ref: 3D-AVD48251

BI-2852

CAS: 2375482-51-0

BI-2852: nanomolar affinity KRAS switch I/II pocket inhibitor; blocks signaling, halts KRAS mutant cell growth.

Formula: C₃₁H₂₈N₆O₂

Purezza: 98.98%

Colore e forma: Solid

Peso molecolare: 516.59

Ref: TM-T10533