CAS 24280-93-1

Acido micofenolico

Descrizione:

Acido micofenolico è un composto organico con la formula chimica C17H20O6 ed è classificato come un immunosoppressore selettivo. È principalmente derivato dal fungo Penicillium ed è noto per il suo ruolo nell'inibizione dell'enzima inosina monofosfato deidrogenasi (IMPDH), che è cruciale nella via di sintesi de novo dei nucleotidi purinici. Questo meccanismo lo rende particolarmente efficace nella prevenzione del rigetto degli organi trapiantati e nel trattamento delle malattie autoimmuni. Acido micofenolico appare come una polvere cristallina bianca o bianco sporco ed è solubile in solventi organici come etanolo e dimetilsolfossido, ma ha una solubilità limitata in acqua. Le sue proprietà farmacologiche includono effetti anti-infiammatori ed è spesso usato in combinazione con altri immunosoppressori per aumentare l'efficacia e ridurre il rischio di rigetto nei pazienti trapiantati. Tuttavia, può anche portare a effetti collaterali come disturbi gastrointestinali e un aumento del rischio di infezioni a causa della sua azione immunosoppressiva. Un monitoraggio adeguato e aggiustamenti della dose sono essenziali durante il suo uso terapeutico.

Formula: C₁₇H₂₀O₆

InChI: InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+

InChI key: InChIKey=HPNSFSBZBAHARI-RUDMXATFSA-N

SMILES: CC1=C2C(=C(O)C(C/C=C(/CCC(O)=O)\C)=C1OC)C(=O)OC2

Sinonimi:

• (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid
• (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
• (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
• (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid
• 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-
• 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
• 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)-
• 6-(4-Hydroxy-6-Methoxy-7-Methyl-3-Oxo-1,3-Dihydro-2-Benzofuran-5-Yl)-4-Methylhex-4-Enoic Acid
• Acide Mycophenolique
• Acido Micofenolico
• Lilly 68618
• MPA
• Melbex
• Mycophenolic Acid From Penicillium Brevi-Compactum
• Mycophenolic Acid From Penicillium*Brevi-Compactu
• Mycophenolinsaure
• Nsc 129185

Mycophenolic Acid

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 320.34

Ref: 3B-M2216

Mycophenolic acid, 98%

CAS: 24280-93-1

It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly

Formula: C₁₇H₂₀O₆

Purezza: 98%

Peso molecolare: 320.34

Ref: 02-J61905

Mycophenolic Acid

CAS: 24280-93-1

Colore e forma: Neat

Ref: 61-FOR1001.06

4-Hexenoic acid,6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 320.3371

Ref: IN-DA00I4O6

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Formula: C₁₇H₂₀O₆

Purezza: 98.79% - 99.77%

Colore e forma: Solid

Peso molecolare: 320.34

Ref: TM-T1335

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid

Purezza: ≥98%

Peso molecolare: 320.34g/mol

Ref: 54-BUP17030

Mycophenolic Acid (Mycophenolate Mofetil EP Impurity F)

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Colore e forma: White To Off-White Solid

Peso molecolare: 320.34

Ref: 4Z-M-163

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid

Colore e forma: White Powder

Peso molecolare: 320.34g/mol

Ref: 54-BI1535

Mycophenolic acid

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Purezza: ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 320.34

Ref: 7W-GA8210

Mycophenolic acid 100 µg/mL in Acetonitrile

Prodotto controllato

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Colore e forma: Single Solution

Peso molecolare: 320.34

Ref: 04-A15391000AL-100

Mycophenolic acid

Prodotto controllato

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Colore e forma: Neat

Peso molecolare: 320.34

Ref: 04-C15391000

(4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid (Mycophenolic Acid)

CAS: 24280-93-1

Colore e forma: Neat

Ref: 86-MM1001.06

Mycophenolic Acid

Prodotto controllato

CAS: 24280-93-1

Applications An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.Environmental contaminants; Food contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),

Formula: C₁₇H₂₀O₆

Colore e forma: White To Off-White

Peso molecolare: 320.34

Ref: TR-M831500

Mycophenolate Mofetil EP Impurity F

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Peso molecolare: 320.34

Ref: ST-EA-CP-M27006

Mycophenolic acid - Bio-X ™

CAS: 24280-93-1

Mycophenolic acid is an immunosuppressant metabolite present in drug formulations that are used to prevent rejections after organ transplants. Mycophenolic acid is a selective inhibitor of inosine monophosphate dehydrogenase (IMPDH) which blocks the conversion of inosine-5-phosphate and xanthine-5-phosphate to guanosine-5-phosphate. This drug inhibits de novo purine biosynthesis. It has also shown to have antibacterial and antifungal properties.

Formula: C₁₇H₂₀O₆

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 320.34 g/mol

Ref: 3D-BM164624

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid is a guanosine monophosphate synthesis pathway blocker. It selectively inhibits inosine monophosphate dehydrogenase (IMPDH) which blocks the conversion of inosine-5-phosphate and xanthine-5-phosphate to guanosine-5-phosphate. This drug inhibits de novo purine biosynthesis. Mycophenolic acid is an immunosuppressant metabolite present in drug formulations that are used to prevent rejections after organ transplants. It has also shown to have antibacterial and antifungal properties.

Formula: C₁₇H₂₀O₆

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 320.34 g/mol

Ref: 3D-FM15781

Mycophenolic Acid

CAS: 24280-93-1

M02087 - Mycophenolic Acid

Formula: C₁₇H₂₀O₆

Purezza: 98%

Colore e forma: Solid, White to off-white powder

Peso molecolare: 320.341

Ref: 10-M02087

Mycophenolic Acid-13C-d3

Prodotto controllato

CAS: 24280-93-1

Applications Mycophenolic Acid-13C-d3 is a labelled Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),

Formula: CC₁₆D₃H₁₇O₆

Colore e forma: Neat

Peso molecolare: 324.348

Ref: TR-M831503

Mycophenolic Acid ((4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid)

CAS: 24280-93-1

Aromatic lactones used as drugs

Formula: C₁₇H₂₀O₆

Colore e forma: White Crystalline Solid

Peso molecolare: 320.12599

Ref: 45-1A06830