CAS 2436-17-1

5-Metossi-3-indolilacetonitrile

Descrizione:

5-Metossi-3-indolilacetonitrile, con il numero CAS 2436-17-1, è un composto chimico che presenta una struttura di indolo, che è un composto biciclico costituito da un anello di benzene fuso a un anello di pirrolo. Questo composto è caratterizzato dalla presenza di un gruppo metossile (-OCH3) nella posizione 5 dell'anello di indolo e di un gruppo acetonitrile (-C≡N) nella posizione 3. Il gruppo metossile contribuisce alla polarità del composto e può influenzare la sua reattività e solubilità in vari solventi. Il gruppo acetonitrile introduce un gruppo funzionale nitrile, noto per la sua capacità di partecipare a reazioni nucleofile e può fungere da blocco di costruzione versatile nella sintesi organica. 5-Metossi-3-indolilacetonitrile può mostrare attività biologica, rendendolo di interesse nella chimica medicinale e nella farmacologia. Le sue proprietà, come il punto di fusione, il punto di ebollizione e la solubilità, possono variare in base alle condizioni specifiche e alla purezza del campione.

Formula: C₁₁H₁₀N₂O

InChI: InChI=1/C11H10N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4H2,1H3

SMILES: COc1ccc2c(c1)c(CC#N)c[nH]2

Sinonimi:

• 5-Methoxyindole-3-acetonitrile
• (5-methoxy-1H-indol-3-yl)acetonitrile

2-(5-methoxy-1H-indol-3-yl)acetonitrile

CAS: 2436-17-1

Formula: C₁₁H₁₀N₂O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 186.2099

Ref: IN-DA006W7A

5-Methoxyindole-3-acetonitrile

CAS: 2436-17-1

Ref: 7W-GK1206

(5-Methoxy-1H-indol-3-yl)acetonitrile

CAS: 2436-17-1

(5-Methoxy-1H-indol-3-yl)acetonitrile

Purezza: ≥95%

Colore e forma: Beige Solid

Peso molecolare: 186.21g/mol

Ref: 54-OR8748

5-Methoxyindole-3-acetonitrile

CAS: 2436-17-1

5-Methoxyindole-3-acetonitrile is a synthetic compound used as a reference for the synthesis of melatonin. It is produced by the addition of magnesium to 5-methoxyindole, followed by reaction with cyanide and nitrile. The synthesis of this compound was first published in 1938 and has since been used as a reference for many other studies. It has been shown that 5-methoxyindole-3-acetonitrile has high performance liquid chromatography properties, with a linear range from 0.5 to 50 mg/mL and an ultraviolet spectrum that falls within the region between 220 nm and 400 nm. A molecular modeling study was conducted on this compound, which showed that it conforms with 4-hydroxy indole ring systems found in natural products such as tryptophan and serotonin. This product also has fluorescent properties, which are caused by its electron withdrawing group (cyano).

Formula: C₁₁H₁₀N₂O

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 186.21 g/mol

Ref: 3D-FM38506

5-Methoxyindole-3-acetonitrile-d2

Prodotto controllato

CAS: 2436-17-1

Applications 5-Methoxyindole-3-acetonitrile-d2 is a labelled analogue of 5-Methoxyindole-3-acetonitrile (M262818), which is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors. 5-Methoxyindole-3-acetonitrile-d2 is also an intermediate in synthesizing Melatonin-d4 (M215002), a hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen re
References Barchas, et al.: Nature, 214, 919 (1967); Glass, J.D., et al.: Science, 214, 821 (1981)

Formula: C₁₁D₂H₈N₂O

Colore e forma: Neat

Peso molecolare: 188.222

Ref: TR-M262819

5-METHOXYINDOLE-3-ACETONITRILE

CAS: 2436-17-1

Formula: C₁₁H₁₀N₂O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 186.214

Ref: 10-F386808

5-Methoxyindole-3-acetonitrile

Prodotto controllato

CAS: 2436-17-1

Applications 5-Methoxyindole-3-acetonitrile is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors.
References Van Zandt, M., et al.: J. Med. Chem., 48, 3141 (2005); Wu, J., et al.: Bioorg. Med. Chem. Lett., 17, 4664 (2007);

Formula: C₁₁H₁₀N₂O

Colore e forma: Neat

Peso molecolare: 186.21

Ref: TR-M262818

5-Methoxyindole-3-acetonitrile

CAS: 2436-17-1

5-Methoxyindole-3-acetonitrile is a versatile building block that can be used for the synthesis of complex compounds. It is a fine chemical that is not commercially available and is sold at high prices as a research chemical. 5-Methoxyindole-3-acetonitrile has been used as a reagent in the synthesis of some pharmaceuticals, such as beta blockers. This compound also has been researched for its potential use as an intermediate in organic syntheses and reactions, including those involving peptides and proteins. The versatility of this chemical makes it useful for the construction of new molecules with medicinal properties.

Formula: C₁₁H₁₀N₂O

Peso molecolare: 186.22 g/mol

Ref: 3D-M-3480

Melatonin Impurity 1

CAS: 2436-17-1

Formula: C₁₁H₁₀N₂O

Peso molecolare: 186.21

Ref: ST-EA-CP-M166004