CAS 24390-14-5

Doxiciclina iclato

Descrizione:

Doxiciclina iclato è un antibiotico ad ampio spettro appartenente alla classe delle tetracicline, utilizzato principalmente per trattare varie infezioni batteriche, comprese le infezioni delle vie respiratorie, le infezioni delle vie urinarie e alcune condizioni della pelle. È caratterizzato dalla sua capacità di inibire la sintesi proteica nei batteri legandosi alla subunità ribosomiale 30S, impedendo così la crescita e la riproduzione dei microrganismi. Doxiciclina iclato è un derivato semisintetico della tetraciclina, che ne migliora la stabilità e l'assorbimento nel tratto gastrointestinale. La sostanza viene tipicamente somministrata per via orale ed è nota per la sua emivita relativamente lunga, che consente una somministrazione una o due volte al giorno. È anche efficace contro alcune infezioni protozoarie ed è utilizzata nel trattamento dell'acne e come profilassi per la malaria. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, fotosensibilità e potenziali effetti sullo sviluppo delle ossa e dei denti nei bambini. Grazie alla sua ampia attività, Doxiciclina iclato è uno strumento prezioso sia in medicina umana che veterinaria.

Formula: C₂₂H₂₄N₂O₈C₂H₆O·ClHH₂O

InChI: InChI=1S/C22H24N2O8.C2H6O.ClH.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;1H;1H2/t7-,10+,14+,15-,17-,22-;;;/m0.../s1

InChI key: InChIKey=JRNIHERUNQWMMW-WBYAVNBMSA-N

SMILES: O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)([C@@H](O)[C@]3(C(=C2O)C(=O)C=4C([C@@H]3C)=CC=CC4O)[H])[H].Cl.C(C)O.O

Sinonimi:

• (1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
• (2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (4S,4Ar,5S,5Ar,6R,12As)-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Hydrochloride
• (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide-ethanol hydrochloride hydrate (2:1:2:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), monohydrate
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,6α,12aα)]-, compd. with ethanol (2:1), monohydrate
• 2-Naphthacenecarboxamide, 4β-(dimethylamino)-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,5β,10,12,12aβ-pentahydroxy-6β-methyl-1,11-dioxo-, monohydrochloride, compd. with ethyl alc. (2:1), monohydrate
• 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Na
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide-Ethanol (2:1) Dihydrochloride Hydrate
• 6-Desoxy-5-hydroxytetracycline hydrochloride hemihydrate hemiethanolate
• Atridox
• BioPure MTAD
• Doryx
• Dox-T 100
• Doxitrat
• Doxy 100
• Doxycycline Hyclate
• Doxycycline Hyclate Monohydrate
• Doxycycline Hydrate
• Doxycycline Hydrochlocide
• Doxycycline Hydrochloride
• Doxycycline Hydrochloride Anhydrous
• Doxycycline Hydrochloride Hemiethanolate Hemihydrate
• Doxycycline hyclate COS
• Doxyprex
• Ethanol, compd. with (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
• Ethanol, compd. with [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
• Monodoks
• Periostat
• Tetraclean

Doxycycline Hyclate

CAS: 10592-13-9, 24390-14-5, 564-25-0

Formula: C₂₂H₂₄N₂O₈C₂H₆O·HClH₂O

Purezza: >97.0%(HPLC)

Colore e forma: Light yellow to Amber to Dark green powder to crystal

Peso molecolare: 512.94

Ref: 3B-D4116

Doxycycline hyclate

CAS: 24390-14-5

Doxycycline hyclate, 24390-14-5, is an antibiotic which inhibits bacterial growth by preventing polypeptide formation. Learn more at Thermo Fisher Scientific.

Formula: C₄₆H₅₈Cl₂N₄O₁₈

Colore e forma: Powder or crystals or crystalline powder, Yellow

Peso molecolare: 1025.88

Ref: 02-J60579

DOXYCYCLINE HYCLATE CRS

CAS: 24390-14-5

DOXYCYCLINE HYCLATE CRS

Formula: C₄₆H₅₈Cl₂N₄O₁₈

Colore e forma: Crystalline Powder. Yellow. Powder.

Peso molecolare: 1025.875

Ref: 41-D3000000

DOXYCYCLINE FOR SYSTEM SUITABILITY CRS

CAS: 24390-14-5

DOXYCYCLINE FOR SYSTEM SUITABILITY CRS

Formula: C₄₆H₅₈Cl₂N₄O₁₈

Colore e forma: Crystalline Powder. Yellow. Powder.

Peso molecolare: 1025.875

Ref: 41-Y0001714

Doxycycline hyclate

CAS: 24390-14-5

Doxycycline hyclate

Formula: C₂₂H₂₄N₂O₈ / C₂₂H₂₅ClN₂O₈

Purezza: 83.1% / 89.9%

Colore e forma: Yellow

Peso molecolare: 444.15327 / 480.12994

Ref: 47-780

Doxycycline Hyclate

CAS: 24390-14-5

Tetracyclines and their derivatives; salts thereof

Formula: C₁₂H₂₄N₂O₈C₂H₆O·ClHH₂O

Colore e forma: Light Yellow Powder

Peso molecolare: 1025.89

Ref: 45-1226003

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1)

CAS: 24390-14-5

Formula: C₄₆H₅₈Cl₂N₄O₁₈

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 1025.8747

Ref: IN-DA0034T4

Doxycycline (hyclate)

CAS: 24390-14-5

Doxycycline (hyclate)

Purezza: ≥95%

Peso molecolare: 512.9g/mol

Ref: 54-BUP17418

Doxycycline hyclate

CAS: 24390-14-5

Doxycycline hyclate

Purezza: 99%

Peso molecolare: 544.982g/mol

Ref: 54-BI12151

Doxycycline hyclate

CAS: 24390-14-5

Formula: C₂₂H₂₄N₂O₈·HCl·5H₂O·5C₂H₆O

Purezza: 95.0 - 102.0 % (C22H25ClN2O8, anhydrous and ethanol free basis)

Colore e forma: Yellow, crystalline powder, hygroscopic

Peso molecolare: 512.94

Ref: 7W-GA1726

Doxycycline Hyclate

CAS: 24390-14-5

Colore e forma: Neat

Ref: 61-FOR0276.00

Doxycycline hyclate 100 µg/mL in Acetonitrile

CAS: 24390-14-5

Formula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O

Colore e forma: Single Solution

Peso molecolare: 1025.87

Ref: 04-A13084280AL-100

Doxycycline hyclate

Prodotto controllato

CAS: 24390-14-5

Formula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O

Colore e forma: Neat

Peso molecolare: 1025.87

Ref: 04-C13084280

PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol

Prodotto controllato

CAS: 101342-45-4, 14206-58-7, 179471-95-5, 2058-46-0, 23313-80-6, 24390-14-5, 41411-66-9, 64-72-2, 64-73-3, 64-75-5

Colore e forma: Mixture

Ref: 04-A30000035ME

Doxycycline Hyclate

Prodotto controllato

CAS: 24390-14-5

Formula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O

Colore e forma: Neat

Peso molecolare: 1025.87

Ref: 86-MM0276.00

Doxycycline (hyclate)

CAS: 24390-14-5

Doxycycline hyclate (WC2031) is a synthetic tetracycline derivative with similar antimicrobial activity. Doxycycline hyclate is also an inhibitor of MMP.

Formula: C₂₂H₂₄N₂O₈·HClC₂H₆OH₂O

Purezza: 97.48% - >99.99%

Colore e forma: Yellow Crystallien Powder

Peso molecolare: 512.90

Ref: TM-T1687L

Doxycycline Hyclate

CAS: 24390-14-5

Formula: C₂₂H₂₄N₂O₈(C₂H₆O)HCl(H₂O)

Peso molecolare: 444.44 : 1/2(46.07) : 36.5 : 1/2(18.0)

Ref: ST-EA-CP-D56008

Doxycycline Hyclate

Prodotto controllato

CAS: 24390-14-5

Applications Antibacterial.
References Fabre, et al.: Chemotherapia, 11, 73 (1966), Goldenthal, et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Polson, A.M., et al.: J. Periodontol., 68, 110 (1997),

Formula: C₂₂H₂₄N₂O₈·C₂H₆O·2ClH·H₂O

Colore e forma: Yellow

Peso molecolare: 1025.87

Ref: TR-D561500

Doxycycline-d3 Hyclate (Major)

Prodotto controllato

CAS: 24390-14-5

Applications Doxycycline-d3 Hyclate, is the labeled analogue of Doxycycline Hyclate (D561500), acting as an Antibacterial.
References Fabre, et al.: Chemotherapia, 11, 73 (1966), Goldenthal, et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Polson, A.M., et al.: J. Periodontol., 68, 110 (1997),

Formula: (C₂₂H₂₁D₃N₂O₈)•2HCl•xH₂O•C₂H₆O

Colore e forma: Neat

Peso molecolare: 2447.452364618

Ref: TR-D561503

Doxycycline hyclate - Bio-X ™

CAS: 24390-14-5

Doxycycline is a tetracycline antibiotic that is used to treat a range of bacterial infections. It is a broad-spectrum antibiotic. This drug inhibits bacterial protein synthesis by binding to its 30S prokaryotic ribosomal subunit. It also inhibits the production of essential proteins required for the bacterial to survive.

Formula: C₂₂H₂₄N₂O₈•HCl•(C₂H₆O)₀•(H₂O)₀

Purezza: Min. 95 Area-%

Colore e forma: Powder

Peso molecolare: 512.94 g/mol

Ref: 3D-BD166236

Doxycycline hyclate

CAS: 24390-14-5

Antibiotic; anti-protozoal; anti-helmintic; protein synthesis inhibitor

Formula: C₂₂H₂₄N₂O₈•HCl•(C₂H₆O)₀•(H₂O)₀

Purezza: Min. 95 Area-%

Colore e forma: Yellow Powder

Peso molecolare: 512.94 g/mol

Ref: 3D-AA22608

Doxycycline Hyclate (DXH), 800U/mg

CAS: 24390-14-5

Formula: C₂₂H₂₄N₂O₈·HClH₂OC₂H₆O

Colore e forma: Yellow, Hygroscopic crystalline powder

Peso molecolare: 512.94

Ref: SR-65094

Doxycycline hydrochloride hemiethanolate hemihydrate, Antibiotic for Culture Media Use Only

CAS: 24390-14-5

Doxycycline is an antibiotic that inhibits bacterial growth by inhibiting protein synthesis, respiratory chain, DNA gyrase, DNA topoisomerase IV. Doxycycline inhibits papaverine by blocking the expression of both cytochrome P450 and epoxide hydrolase. Doxycycline is commonly found in studies for bacterial infections, drug therapy, histopathological studies, cell culture and chemometric analysis.

Formula: C₂₂H₂₄N₂O₈·HClH₂OC₂H₆O

Purezza: Min. 97.0 Area-%

Peso molecolare: 512.90 g/mol

Ref: 3D-Q-201047