CAS 24390-14-5

Doxiciclina iclato

Descrizione:

Doxiciclina iclato è un antibiotico ad ampio spettro appartenente alla classe delle tetracicline, utilizzato principalmente per trattare varie infezioni batteriche, comprese le infezioni delle vie respiratorie, le infezioni delle vie urinarie e alcune condizioni della pelle. È caratterizzato dalla sua capacità di inibire la sintesi proteica nei batteri legandosi alla subunità ribosomiale 30S, impedendo così la crescita e la riproduzione dei microrganismi. Doxiciclina iclato è un derivato semisintetico della tetraciclina, che ne migliora la stabilità e l'assorbimento nel tratto gastrointestinale. La sostanza viene tipicamente somministrata per via orale ed è nota per la sua emivita relativamente lunga, che consente una somministrazione una o due volte al giorno. È anche efficace contro alcune infezioni protozoarie ed è utilizzata nel trattamento dell'acne e come profilassi per la malaria. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, fotosensibilità e potenziali effetti sullo sviluppo delle ossa e dei denti nei bambini. Grazie alla sua ampia attività, Doxiciclina iclato è uno strumento prezioso sia in medicina umana che veterinaria.

Formula: C₂₂H₂₄N₂O₈C₂H₆O·ClHH₂O

InChI: InChI=1S/C22H24N2O8.C2H6O.ClH.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;1H;1H2/t7-,10+,14+,15-,17-,22-;;;/m0.../s1

InChI key: InChIKey=JRNIHERUNQWMMW-WBYAVNBMSA-N

SMILES: O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)([C@@H](O)[C@]3(C(=C2O)C(=O)C=4C([C@@H]3C)=CC=CC4O)[H])[H].Cl.C(C)O.O

Sinonimi:

• (1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
• (2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (4S,4Ar,5S,5Ar,6R,12As)-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Hydrochloride
• (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide-ethanol hydrochloride hydrate (2:1:2:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), monohydrate
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,6α,12aα)]-, compd. with ethanol (2:1), monohydrate
• 2-Naphthacenecarboxamide, 4β-(dimethylamino)-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,5β,10,12,12aβ-pentahydroxy-6β-methyl-1,11-dioxo-, monohydrochloride, compd. with ethyl alc. (2:1), monohydrate
• 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Na
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide-Ethanol (2:1) Dihydrochloride Hydrate
• 6-Desoxy-5-hydroxytetracycline hydrochloride hemihydrate hemiethanolate
• Atridox
• BioPure MTAD
• Doryx
• Dox-T 100
• Doxitrat
• Doxy 100
• Doxycycline Hyclate
• Doxycycline Hyclate Monohydrate
• Doxycycline Hydrate
• Doxycycline Hydrochlocide
• Doxycycline Hydrochloride
• Doxycycline Hydrochloride Anhydrous
• Doxycycline Hydrochloride Hemiethanolate Hemihydrate
• Doxycycline hyclate COS
• Doxyprex
• Ethanol, compd. with (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
• Ethanol, compd. with [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
• Monodoks
• Periostat
• Tetraclean

Doxycycline hyclate

CAS: 24390-14-5

Antibiotic; anti-protozoal; anti-helmintic; protein synthesis inhibitor

Formula: C₂₂H₂₄N₂O₈•HCl•(C₂H₆O)₀•(H₂O)₀

Purezza: Min. 95 Area-%

Colore e forma: Yellow Powder

Peso molecolare: 512.94 g/mol

Ref: 3D-AA22608

Doxycycline Hyclate (DXH), 800U/mg

CAS: 24390-14-5

Formula: C₂₂H₂₄N₂O₈·HClH₂OC₂H₆O

Colore e forma: Yellow, Hygroscopic crystalline powder

Peso molecolare: 512.94

Ref: SR-65094

Doxycycline hydrochloride hemiethanolate hemihydrate, Antibiotic for Culture Media Use Only

CAS: 24390-14-5

Doxycycline is an antibiotic that inhibits bacterial growth by inhibiting protein synthesis, respiratory chain, DNA gyrase, DNA topoisomerase IV. Doxycycline inhibits papaverine by blocking the expression of both cytochrome P450 and epoxide hydrolase. Doxycycline is commonly found in studies for bacterial infections, drug therapy, histopathological studies, cell culture and chemometric analysis.

Formula: C₂₂H₂₄N₂O₈·HClH₂OC₂H₆O

Purezza: Min. 97.0 Area-%

Peso molecolare: 512.90 g/mol

Ref: 3D-Q-201047