CAS 24697-74-3

Leonurina

Descrizione:

Leonurina, con il numero CAS 24697-74-3, è un alcaloide che si trova naturalmente, derivato principalmente dalla pianta Leonurus cardiaca, comunemente nota come erba madre. Questo composto è caratterizzato dalle sue caratteristiche strutturali, che includono un anello di piridina e un gruppo idrossile fenolico, contribuendo alla sua attività biologica. Leonurina è noto per le sue potenziali proprietà farmacologiche, inclusi effetti anti-infiammatori, antiossidanti e neuroprotettivi. È stato studiato per le sue possibili applicazioni nella medicina tradizionale, in particolare nel trattamento dei disturbi cardiovascolari e neurologici. Inoltre, Leonurina presenta effetti sedativi lievi, che possono essere benefici per l'ansia e il sollievo dallo stress. La sua solubilità in acqua è limitata, il che può influenzare la sua biodisponibilità e l'efficacia terapeutica. Con il proseguire della ricerca, si sta esplorando l'intero spettro dei suoi effetti e meccanismi d'azione, evidenziando l'importanza dei composti naturali nello sviluppo di farmaci e applicazioni terapeutiche.

Formula: C₁₄H₂₁N₃O₅

InChI: InChI=1S/C14H21N3O5/c1-20-10-7-9(8-11(21-2)12(10)18)13(19)22-6-4-3-5-17-14(15)16/h7-8,18H,3-6H2,1-2H3,(H4,15,16,17)

InChI key: InChIKey=WNGSUWLDMZFYNZ-UHFFFAOYSA-N

SMILES: C(OCCCCNC(=N)N)(=O)C1=CC(OC)=C(O)C(OC)=C1

Sinonimi:

• 24697-74-3
• 4-Carbamimidamidobutyl 4-Hydroxy-3,5-Dimethoxybenzoate Hydrochloride Hydrate
• 4-Carbamimidamidobutyl-4-hydroxy-3,5-dimethoxybenzolcarboxylat
• 4-Guanidino-1-butanol Syringate
• 4-Hydroxy-3,5-dimethoxybenzoic Acid 4-[(Aminoiminomethyl)amino]butyl Ester
• 4-Hydroxy-3,5-dimethoxybenzoic Acid d-Guanidinobutyl Ester
• 4-[(Diaminomethylidene)Amino]Butyl 4-Hydroxy-3,5-Dimethoxybenzoate
• Benzoic Acid, 4-Hydroxy-3,5-Dimethoxy-, 4-[(Aminoiminomethyl)Amino]Butyl Ester
• Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ester with (4-hydroxybutyl)guanidine
• Guanidine, (4-hydroxybutyl)-, 4-hydroxy-3,5-dimethoxybenzoate
• Guanidine, (4-hydroxybutyl)-, 4-hydroxy-3,5-dimethoxybenzoate (ester)
• Leonurin
• Leonurine
• Scm 198
• Syringic Acid d-Guanidinobutyl Ester

Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-[(aminoiminomethyl)amino]butyl ester

CAS: 24697-74-3

Formula: C₁₄H₂₁N₃O₅

Purezza: %

Colore e forma: Solid

Peso molecolare: 311.3336

Ref: IN-DA002P1O

4-Guanidinobutyl 4-Hydroxy-3,5-Dimethoxybenzoate

CAS: 24697-74-3

4-Guanidinobutyl 4-Hydroxy-3,5-Dimethoxybenzoate

Purezza: 99%

Peso molecolare: 311.33g/mol

Ref: 54-OR1027299

Leonurine

CAS: 24697-74-3

Formula: C₁₄H₂₂CLN₃O₅

Peso molecolare: 347.80

Ref: 7W-GY7471

Leonurine

CAS: 24697-74-3

Leonurine

Purezza: ≥98%

Peso molecolare: 311.33g/mol

Ref: 54-BUP10292

Leonurine

CAS: 24697-74-3

Leonurine hydrochloride has anti-oxidative, anti-inflammatory, and antitumor activities, it exerts antidiabetic, cardiovascular, and bovine mastitis protection, it has an inhibitory effect on bleeding caused by incomplete abortion. Leonurine hydrochloride increases the expression levels of caspase-3, caspase-9 and Bax/Bcl-2, and it inhibits osteoclastogenesis and prevent osteoporosis associated with estrogen deficiency by inhibiting the NF-κB and PI3K/Akt signaling pathways.

Formula: C₁₄H₂₁N₃O₅

Purezza: 95%~99%

Peso molecolare: 311.338

Ref: BP-BP0850

Leonurine

CAS: 24697-74-3

Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.

Formula: C₁₄H₂₁N₃O₅

Purezza: 98.55%

Colore e forma: White Crystalline Powder

Peso molecolare: 311.33

Ref: TM-T5S2102

Leonurine

CAS: 24697-74-3

Formula: C₁₄H₂₁N₃O₅

Purezza: 95.0%

Colore e forma: Solid, Powder

Peso molecolare: 311.338

Ref: 10-F078382

Leonurine

Prodotto controllato

CAS: 24697-74-3

Applications Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases.
References He, C., et al.: Zhongguo Linchuang Yaolixue Yu Zhiliaoxue, 18, 1419 (2013); Nsuala, B. N., et al.: J. Ethnopharmacol., 174, 520 (2015); Sun, Y., et al.; Eur. J. Drug Metabo. Pharmacokinet., 41, 423 (2016)

Formula: C₁₄H₂₁N₃O₅

Colore e forma: Neat

Peso molecolare: 311.33

Ref: TR-L329603

Leonurine

CAS: 24697-74-3

Leonurine is a polyphenolic compound that belongs to the group of natural compounds. It has been shown to have neuroprotective effects in vitro by inhibiting neuronal death at low doses. Leonurine also blocks the oxidative injury pathway, which may be related to its ability to inhibit apoptosis and reduce atherosclerotic lesion size in mice. In addition, leonurine inhibits the p-hydroxybenzoic acid (PHBA) oxidation pathway, which may contribute to its anti-inflammatory activities. Leonurine binds with high affinity and specificity to toll-like receptor 4 (TLR4), which may be related to its immunosuppressive properties.

Purezza: Min. 95%

Ref: 3D-FL73876