CAS 247068-82-2

1,1-Dimetiletil N-[(1S)-3-metil-1-[[(2R)-2-metil-2-ossiranyl]carbonil]butil]carbammato

Descrizione:

1,1-Dimetiletil N-[(1S)-3-metil-1-[[(2R)-2-metil-2-ossiranyl]carbonil]butil]carbammato, con numero CAS 247068-82-2, è un composto chimico caratterizzato dalla sua struttura complessa, che include un gruppo funzionale carbammato e una parte epossidica. Questo composto presenta una catena alchilica ramificata, contribuendo al suo ingombro sterico e potenzialmente influenzando la sua reattività e solubilità. La presenza dell'anello epossido suggerisce che potrebbe partecipare a reazioni nucleofile, rendendolo un candidato per varie applicazioni sintetiche. Inoltre, la stereochimica indicata dalle designazioni (1S) e (2R) implica che il composto presenta chiralità, che può influenzare la sua attività biologica e le interazioni con altre molecole. La struttura molecolare complessiva suggerisce usi potenziali in prodotti farmaceutici o agrochimici, dove interazioni specifiche con sistemi biologici sono cruciali. Tuttavia, sarebbero necessari studi dettagliati sulle sue proprietà fisiche, come punto di fusione, punto di ebollizione e solubilità, per comprendere appieno il suo comportamento in diversi ambienti.

Formula: C₁₄H₂₅NO₄

InChI: InChI=1S/C14H25NO4/c1-9(2)7-10(11(16)14(6)8-18-14)15-12(17)19-13(3,4)5/h9-10H,7-8H2,1-6H3,(H,15,17)/t10-,14+/m0/s1

InChI key: InChIKey=DDMPMIMTLBGEHT-IINYFYTJSA-N

SMILES: C([C@@H](NC(OC(C)(C)C)=O)CC(C)C)(=O)[C@@]1(C)CO1

Sinonimi:

• (2R)-2-[(2S)-2-(tert-Butoxycarbonylamino)-4-methylpentanoyl]-2-methyloxirane
• 1,1-Dimethylethyl N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]carbamate
• Boc-L-leucine epoxyketone
• Boc-Leucine-epoxylketone
• Carbamic acid, N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-dimethylethyl ester
• Carbamic acid, [(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-, 1,1-dimethylethyl ester
• Carfilzomib intermediate 1
• Tert-Butyl 4-Methyl-1-(2-Methyloxiran-2-Yl)-1-Oxopentan-2-Ylcarbamate
• Tert-butyl N-[(2s)-4-methyl-1-[(2r)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]carbamate
• [3-Methyl-1-(2-methyl-oxiranecarbonyl)-butyl]-carbamic acid tert-butyl ester
• tert-butyl (S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylcarbamate

CarbaMic acid, N-[(1S)-3-Methyl-1-[[(2R)-2-Methyl-2-oxiranyl]carbonyl]butyl]-, 1,1-diMethylethyl ester

CAS: 247068-82-2

Formula: C₁₄H₂₅NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 271.3526

Ref: IN-DA002P3R

Tert-Butyl ((S)-4-Methyl-1-((R)-2-Methyloxiran-2-Yl)-1-Oxopentan-2-Yl)Carbamate

CAS: 247068-82-2

Tert-Butyl ((S)-4-Methyl-1-((R)-2-Methyloxiran-2-Yl)-1-Oxopentan-2-Yl)Carbamate

Purezza: 98%

Peso molecolare: 271.35g/mol

Ref: 54-OR1029417

(2S)-2-(Boc-amino)-4-Methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentane ee

CAS: 247068-82-2

Versatile small molecule scaffold

Formula: C₁₄H₂₅NO₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 271.35 g/mol

Ref: 3D-XJA06882

tert-Butyl ((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

CAS: 247068-82-2

Formula: C₁₄H₂₅NO₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 271.357

Ref: 10-F497427

tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

Prodotto controllato

CAS: 247068-82-2

Applications tert-Butyl ((S)-4-Methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
References Wang, P., et al.: Process for preparation of carfilzomib, China Patent 2015010436, Jan 29, 2015; Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012)

Formula: C₁₄H₂₅NO₄

Colore e forma: Neat

Peso molecolare: 271.35

Ref: TR-B809210

Carfilzomib Impurity 23

CAS: 247068-82-2

Formula: C₁₄H₂₅NO₄

Peso molecolare: 271.36

Ref: ST-EA-CP-C153025

tert-Butyl ((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate

CAS: 247068-82-2

tert-Butyl ((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)carbamate is a useful organic compound for research related to life sciences. The catalog number is T66629 and the CAS number is 247068-82-2.

Formula: C₁₄H₂₅NO₄

Colore e forma: Solid

Peso molecolare: 271.357

Ref: TM-T66629