CAS 249537-73-3

H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-Oh

Descrizione:

La sostanza indicata come "H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-Oh" con il numero CAS 249537-73-3 è un peptide, specificamente una sequenza di amminoacidi legati da legami peptidici. Questo composto presenta una varietà di amminoacidi, tra cui metionina (Met), alanina (Ala), glicina (Gly), prolina (Pro), istidina (His), valina (Val), isoleucina (Ile), treonina (Thr) e acido glutammico (Glu). La presenza di prolina suggerisce rigidità strutturale, mentre le diverse catene laterali degli altri amminoacidi contribuiscono alla sua potenziale attività biologica e interazioni. Il prefisso "H-" indica che il peptide è probabilmente nella sua forma protetta, mentre l'"Oh" alla fine suggerisce la presenza di un gruppo idrossile, che può influenzare la sua solubilità e reattività. I peptidi come questo possono svolgere ruoli significativi nei processi biologici, inclusi segnalazione, attività enzimatica e comunicazione cellulare, rendendoli di interesse in campi come la biochimica e la farmacologia.

NFAT Inhibitor

CAS: 249537-73-3

The flow of information from calcium-mobilizing receptors to nuclear factor of activated T cells (NFAT)-dependent genes is critically dependent on interaction between the phosphatase calcineurin and the transcription factor NFAT. The high-affinity calcineurin-binding peptide potently inhibited NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT. NFAT inhibitors may be useful in treating chronic ailments such as myocardial hypertrophy, allergy, arthritis, and autoimmune disease.

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Purezza: 98.2%

Colore e forma: White Powder

Peso molecolare: 1683.95

Ref: 01-4034010

NFAT Inhibitor-1

CAS: 249537-73-3

Formula: C₇₅H₁₂₀N₂₀O₂₂S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1685.9411

Ref: IN-DA00BERD

NFAT Inhibitor

CAS: 249537-73-3

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Peso molecolare: 1683.93

Ref: 7W-GL0293

NFAT Inhibitor

CAS: 249537-73-3

NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Purezza: 98.26%

Colore e forma: Solid

Peso molecolare: 1683.93

Ref: TM-TP1015

NFAT Inhibitor

CAS: 249537-73-3

NFAT Inhibitor

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Purezza: 98% (Typical Value in Batch COA)

Colore e forma: white solid

Peso molecolare: 1,797.95g/mol

Ref: 54-BISN0319

NFAT Inhibitor trifluoroacetate salt

CAS: 249537-73-3

NFAT Inhibitor trifluoroacetate salt H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu (NFAT) is an inhibitor drug that has been shown to inhibit the nuclear factor of activated T cells (NFAT). NFAT is a transcriptional regulator that controls the expression of inflammatory genes in macrophages and other cell types. NFAT inhibitors have been shown to be effective for treating bowel diseases, such as ulcerative colitis and Crohn's disease, by inhibiting the activation of macrophages. NFAT inhibitors are also used in vitro as a tool for studying cellular signaling pathways. The most common type of NFAT inhibitor is fluconazole, which blocks calcineurin activity and prevents the activation of NFAT. However, other types of inhibitors are being developed, including mmp9 activity or

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Purezza: Min. 95%

Peso molecolare: 1,683.93 g/mol

Ref: 3D-FN109384