CAS 2515-18-6

4-β-Hydroxy Cholesterol 4-Acetate

CAS: 2515-18-6

Formula: C₂₉H₄₈O₃

Peso molecolare: 444.70

Ref: 4Z-C-5391

4β-Hydroxy Cholesterol 4-Acetate

Prodotto controllato

CAS: 2515-18-6

Applications Cholesterol (C432501) metabolite. Hydroximinosteroid analog with cytotoxic properties.
References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001), Poza, J. et al.: Bioorgan Med. Chem. 15, 4722 (2007)

Formula: C₂₉H₄₈O₃

Colore e forma: Neat

Peso molecolare: 444.69

Ref: TR-H917985

4β-Hydroxy cholesterol 4-acetate

Prodotto controllato

CAS: 2515-18-6

4b-Hydoxy cholesterol 4-acetate is a pleiotropic drug with a wide range of pharmacological activities. It is an inhibitor of the sirtuin family of proteins and may have anti-cancer effects. It has also been shown to be effective in the treatment of depression and myelodysplastic syndrome. The mechanism of action for this agent is not well understood, but it may be due to its ability to inhibit DNA methyltransferases, which would lead to a change in DNA methylation patterns. 4b-Hydroxy cholesterol 4-acetate has also been shown to decrease lipid levels in the blood and increase the activity of liver enzymes that metabolize fatty acids. This drug can also modify lamellar bodies and short-chain fatty acids by inhibiting the enzyme ATP citrate lyase, which catalyzes citrate cleavage into acetyl CoA and oxaloacetate.

Formula: C₂₉H₄₈O₃

Purezza: Min. 95%

Peso molecolare: 444.69 g/mol

Ref: 3D-FH23949