CAS 25507-04-4

Clindamicina palmitato cloridrato

Descrizione:

Clindamicina palmitato cloridrato è un antibiotico semisintetico derivato dalla lincomicina, utilizzato principalmente per trattare varie infezioni batteriche, in particolare quelle causate da batteri anaerobi e da alcune ceppi di streptococchi. È caratterizzato dalla sua forma di polvere cristallina bianca a bianco sporco, solubile in acqua e stabile in condizioni normali di stoccaggio. La sostanza agisce inibendo la sintesi proteica batterica, esercitando così i suoi effetti antimicrobici. Clindamicina palmitato cloridrato viene spesso somministrato in formulazioni orali, rendendolo adatto per l'uso pediatrico grazie al suo estere di palmitato, che ne migliora il sapore e la palatabilità. La forma di sale cloridrato ne migliora la solubilità e la biodisponibilità. Come per qualsiasi antibiotico, è essenziale utilizzare Clindamicina palmitato cloridrato in modo giudizioso per prevenire lo sviluppo di resistenza agli antibiotici. Gli effetti collaterali potenziali possono includere disturbi gastrointestinali e reazioni allergiche, richiedendo un attento monitoraggio durante il trattamento. In generale, è un agente terapeutico prezioso nella gestione di infezioni specifiche, in particolare nei pazienti allergici alla penicillina.

Formula: C₃₄H₆₃ClN₂O₆S·ClH

InChI: InChI=1S/C34H63ClN2O6S.ClH/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-21-27(38)42-32-30(40)29(39)31(43-34(32)44-5)28(24(3)35)36-33(41)26-22-25(20-7-2)23-37(26)4;/h24-26,28-32,34,39-40H,6-23H2,1-5H3,(H,36,41);1H/t24-,25+,26-,28+,29+,30-,31+,32+,34+;/m0./s1

InChI key: InChIKey=GTNDZRUWKHDICY-DJHAJVGHSA-N

SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)([C@H](C)Cl)[C@]2(O[C@H](SC)[C@H](OC(CCCCCCCCCCCCCCC)=O)[C@@H](O)[C@H]2O)[H].Cl

Sinonimi:

• <span class="text-smallcaps">L</smallcap>-threo-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, 2-palmitate, monohydrochloride, trans-α-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride, (2S-trans)-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride
• Cleocin Pediatric
• Clindamycin 2-palmitate hydrochloride
• Clindamycin palmitate hydrochloride
• Palmitic acid, 2-ester with methyl 7-chloro-6,7,8-trideoxy-6-(trans-1-methyl-4-propyl-<span class="text-smallcaps">L</smallcap>-2-pyrrolidinecarboxamido)-1-thio-<smallcap>L</smallcap>-threo-α-<smallcap>D</span>-galacto-octopyranoside monohydrochloride
• [(2R,3R,4S,5R,6R)-6-[2-chloro-1-[[(2S,4R)-1-methyl-4-propyl-pyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyl-tetrahydropyran-3-yl] hexadecanoate hydrochloride
• methyl 7-chloro-6,7,8-trideoxy-2-O-hexadecanoyl-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-alpha-D-galacto-octopyranoside hydrochloride (1:1)
• methyl 7-chloro-6,7,8-trideoxy-2-O-hexadecanoyl-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-beta-L-erythro-octopyranoside hydrochloride (1:1)
• L-threo-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, 2-palmitate, monohydrochloride, trans-α-
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride, (2S-trans)-

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Antibiotics nesoi

Formula: C₃₄H₆₃ClN₂O₆S·HCl

Colore e forma: White Off-White Powder

Peso molecolare: 662.40954

Ref: 45-1137005

Clindamycin 2-Palmitate

CAS: 25507-04-4

Formula: C₃₄H₆₃ClN₂O₆S·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 663.41 36.46

Ref: 4Z-C-5026

Clindamycin palmitate hydrochloride

CAS: 25507-04-4

Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is the hydrochloride salt of clindamycin and palmitate, a lincosamide antibiotic.

Formula: C₃₄H₆₃ClN₂O₆S·HCl

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 699.85

Ref: TM-T6449

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Colore e forma: Neat

Ref: 61-FOR1989.00

Clindamycin Palmitate Hydrochloride

Prodotto controllato

CAS: 25507-04-4

Formula: C₃₄H₆₃ClN₂O₆S·ClH

Colore e forma: Neat

Peso molecolare: 699.85

Ref: 86-MM1989.00

Clindamycin Palmitate Hydrochloride

Prodotto controllato

CAS: 25507-04-4

Applications Clindamycin Palmitate is a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial.
References Platzer, D., et al.: J. Pharm. Biomed. Anal., 41, 84 (2006),

Formula: C₃₄H₆₃ClN₂O₆S·ClH

Colore e forma: Neat

Peso molecolare: 699.85

Ref: TR-C580035

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Formula: C₃₄H₆₃ClN₂O₆SHCl

Peso molecolare: 663.4 : 36.5

Ref: ST-EA-CP-C26050