CAS 2648407-76-3

GT-02216

CAS: 2648407-76-3

GT-02216 is capable of binding allosterically to GCase, thereby enhancing its function. In primary human fibroblasts, it increases GCase activity and decreases Tau accumulation in mutant GBA1 fibroblasts. Additionally, GT-02216 offers protection to hippocampal primary neurons exposed to Tau oligomer in a rat model.

Formula: C₂₂H₂₃N₅O₂

Colore e forma: Solid

Peso molecolare: 389.45

Ref: TM-T211168