CAS 2657-25-2

4'-Idrossicalcone

Descrizione:

4'-Idrossicalcone è un composto organico appartenente alla famiglia dei chalconi, caratterizzato dalla sua struttura che presenta uno scheletro di chalcone con un gruppo idrossile nella posizione para dell'anello fenilico. Appare tipicamente come un solido cristallino di colore giallo-arancio ed è noto per le sue potenziali attività biologiche, comprese le proprietà antiossidanti, antinfiammatorie e antimicrobiche. Il composto è solubile in solventi organici come etanolo e metanolo, ma ha una solubilità limitata in acqua. La sua formula molecolare è C15H12O2 e ha un peso molecolare relativamente basso. 4'-Idrossicalcone è spesso studiato per il suo ruolo in vari percorsi biochimici e le sue potenziali applicazioni in prodotti farmaceutici e nutraceutici. Inoltre, funge da precursore nella sintesi di altri flavonoidi e composti bioattivi. La reattività del composto può essere attribuita alla presenza del gruppo idrossile, che può partecipare a legami idrogeno e influenzare la sua interazione con obiettivi biologici.

Formula: C₁₅H₁₂O₂

InChI: InChI=1/C15H12O2/c16-14-9-7-13(8-10-14)15(17)11-6-12-4-2-1-3-5-12/h1-11,16H/b11-6+

InChI key: InChIKey=UAHGNXFYLAJDIN-UHFFFAOYSA-N

SMILES: C(C=CC1=CC=CC=C1)(=O)C2=CC=C(O)C=C2

Sinonimi:

• (2E)-1-(4-hydroxyphenyl)-3-phenylprop-2-en-1-one
• 1-(4-Hydroxyphenyl)-3-Phenylprop-2-En-1-One
• 1-(4-Hydroxyphenyl)-3-phenyl-2-propen-1-one
• 1-(4-Hydroxyphenyl)-3-phenylpropenone
• 2-Propen-1-one, 1-(4-hydroxyphenyl)-3-phenyl-
• 4-Hydroxyphenyl styryl ketone
• Benzylidene-(4-hydroxyacetophenone)
• Chalcone, 4′-hydroxy-
• NSC 242264
• p-Cinnamoylphenol
• 4′-Hydroxychalcone
• HYDROXYCHALCONE, 4'-
• 4'-Hydroxychalcone98%
• 2-BENZAL-4'-HYDROXYACETOPHENONE
• 1-(p-Hydroxyphenyl)-3-phenyl-2-propene-1-one
• 2-BENZYLIDENE-4'-HYDROXYACETOPHENONE
• HYDROXYCHALCONE, 4-(RG)
• 4'-Hydroxychalcone,97%

4'-Hydroxychalcone

CAS: 2657-25-2

Formula: C₁₅H₁₂O₂

Purezza: >95.0%(GC)

Colore e forma: Light orange to Yellow to Green powder to crystal

Peso molecolare: 224.26

Ref: 3B-H0945

4'-Hydroxychalcone, 97%

CAS: 2657-25-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₅H₁₂O₂

Purezza: 97%

Colore e forma: Crystals or powder or crystalline powder, White to pale yellow

Peso molecolare: 224.26

Ref: 02-A10838

2-Propen-1-one, 1-(4-hydroxyphenyl)-3-phenyl-

CAS: 2657-25-2

Formula: C₁₅H₁₂O₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 224.2546

Ref: IN-DA002TQO

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone

Purezza: ≥98%

Peso molecolare: 224.25g/mol

Ref: 54-BUP16799

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone

Formula: C₁₅H₁₂O₂

Purezza: 98%

Colore e forma: Pale Yellow Powder

Peso molecolare: 224.25g/mol

Ref: 54-OR2345

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity

Formula: C₁₅H₁₂O₂

Purezza: 99.86% - 99.87%

Colore e forma: Yellow-Cream Powder

Peso molecolare: 224.25

Ref: TM-T7917

4'-Hydroxychalcone

CAS: 2657-25-2

4'-Hydroxychalcone is a compound that has shown to be an insulin resistance suppressant. It reduces the activity of recombinant cytochrome P450 enzymes and blocks hydroxy group metabolism, which leads to a decrease in ATP levels. This molecule also has biological properties as it can inhibit the expression of β-catenin and induce apoptosis in cancer cells. 4'-Hydroxychalcone has been found to inhibit the transfer mechanism of phosphatidylinositol 3-kinase (PTP1B) and is able to bind with the protein marker p62/SQSTM1.
4'-Hydroxychalcone is a potent inhibitor for PTP1B, which is a negative regulator for insulin signaling pathways. In addition, 4'-hydroxychalcone can bind with p62/SQSTM1, which is a marker for autophagy proteins. These properties have been shown to have anti-cancer effects on multiple cancer types including

Formula: C₁₅H₁₂O₂

Colore e forma: Powder

Peso molecolare: 224.25 g/mol

Ref: 3D-FH36595

4′-Hydroxychalcone

CAS: 2657-25-2

Formula: C₁₅H₁₂O₂

Purezza: 97%

Colore e forma: Solid, Yellow-cream powder

Peso molecolare: 224.259

Ref: 10-F003112