CAS 26662-94-2

1-palmitoil-2-oleoil-sn-glicero-3-fosfoetanolamina

Descrizione:

1-palmitoil-2-oleoil-sn-glicero-3-fosfoetanolamina, comunemente noto come POPE, è un fosfolipide che svolge un ruolo cruciale nelle membrane cellulari, in particolare nella formazione di doppie membrane lipidiche. È caratterizzato dalla sua natura anfifilica, possedendo sia regioni idrofili (il gruppo testa della fosfoetanolamina) che regioni idrofobiche (le code degli acidi grassi), il che facilita la sua integrazione nelle membrane lipidiche. La struttura include una catena di palmitoil saturata e una catena di oleoil insaturata, contribuendo alla sua fluidità e stabilità negli ambienti di membrana. Il POPE è spesso utilizzato negli studi biofisici e nella formulazione di liposomi per la somministrazione di farmaci grazie alla sua biocompatibilità e capacità di formare vescicole stabili. Inoltre, è coinvolto in vari processi biologici, inclusa la fusione delle membrane e le vie di segnalazione. Il suo numero CAS, 26662-94-2, è un identificatore unico che aiuta nella catalogazione e nel riferimento di questa specifica sostanza chimica nella letteratura scientifica e nei database.

Formula: C₃₉H₇₆NO₈P

InChI: InChI=1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-/t37-/m1/s1

InChI key: InChIKey=FHQVHHIBKUMWTI-OTMQOFQLSA-N

SMILES: [C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O

Sinonimi:

• (R)-1-((((2-Aminoethoxy)hydroxyphosphinyl)oxy)methyl)-2-((1-oxohexadecyl)oxy)ethyl oleate
• 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine
• 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphorylethanolamine
• 1-Palmitoyl-2-oleoyl-sn-glyceryl-3-phosphorylethanolamine
• 1-Palmitoyl-2-oleoylphosphatidylethanolamine
• 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphatidylethanolamine
• 9-Octadecenoic acid (9Z)-, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester
• 9-Octadecenoic acid (Z)-, 1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester, (R)-
• <span class="text-smallcaps">L</span>-α-1-Palmitoyl-2-oleoylglycerophosphoethanolamine
• Ethanol, 2-amino-, dihydrogen phosphate (ester) monoester with 1-palmito-2-olein, <span class="text-smallcaps">L</span>-
• Olein, 1-palmito-2-, dihydrogen phosphate mono(2-aminoethyl) ester, <span class="text-smallcaps">L</span>-
• Palmitin, 2-oleo-1-, dihydrogen phosphate mono(2-aminoethyl) ester, <span class="text-smallcaps">L</span>-
• Pe(16:0/18:1(9Z))
• Phosphatidyl-β-oleoyl-γ-palmitoyl ethanolamine
• Phosphatidylethanolamine (16:0/18:1)
• Olein, 1-palmito-2-, dihydrogen phosphate mono(2-aminoethyl) ester, L-
• Palmitin, 2-oleo-1-, dihydrogen phosphate mono(2-aminoethyl) ester, L-

POPE

CAS: 26662-94-2

POPE(1-Palmitoyl-2-oleoyl-sn-glycero-3-PE) is a compound found in Escherichia coli, part of the cell membrane, and can be used to study changes in cell membrane permeability.

Formula: C₃₉H₇₆NO₈P

Purezza: 97% - 98.02%

Colore e forma: Solid

Peso molecolare: 718

Ref: TM-TF0083

1-HEXADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

CAS: 26662-94-2

Formula: C₃₉H₇₆NO₈P

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 717.9964

Ref: IN-DA00BG77

2-Oleoyl-1-Palmitoyl-sn-Glycero-3-Phosphoethanolamine

CAS: 26662-94-2

2-Oleoyl-1-Palmitoyl-sn-Glycero-3-Phosphoethanolamine

Purezza: 97%

Peso molecolare: 718.00g/mol

Ref: 54-OR1010577

POPE

CAS: 26662-94-2

POPE

Purezza: ≥95%

Peso molecolare: 718g/mol

Ref: 54-BUP11134

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine

CAS: 26662-94-2

Formula: C39H76NO8P

Purezza: >98%

Colore e forma: Solid

Peso molecolare: 718

Ref: 48-37-1828

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphoethanolamine

CAS: 26662-94-2

Formula: C₃₉H₇₆NO₈P

Peso molecolare: 718.01

Ref: 4Z-P-312001

POPE

Prodotto controllato

CAS: 26662-94-2

Stability Light Sensitive, Moisture Sensitive
Applications POPE is a component of E. Coli bacteria cell membrane.
References Tu, Y., et al.: Nature Nanotechnology, 8, 594 (2013).

Formula: C₃₉H₇₆NO₈P

Colore e forma: Neat

Peso molecolare: 718.0

Ref: TR-P689510

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine

CAS: 26662-94-2

1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine is a broad spectrum antimicrobial that has been shown to have binding properties to peptides. This compound can be used as a potential antimicrobial for the treatment of bacterial infections and gramicidin, an antibiotic that is active against bacteria. It has also been shown to permeabilize cell membranes, which may lead to its function as an antimicrobial agent. 1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphatidylethanolamine is water soluble and has been shown to have conformational properties. These conformational properties are responsible for its binding activity with peptides. 1POGPE is stable in both calorimetric assays and bilayers, which allows it to maintain its structure when interacting with other compounds. 1POGPE also has a high affinity for

Formula: C₃₉H₇₆NO₈P

Purezza: Min. 95%

Peso molecolare: 718 g/mol

Ref: 3D-BBA66294