CAS 26807-65-8

Indapamide

Descrizione:

Indapamide è un diuretico simile alle tiazidi utilizzato principalmente nel trattamento dell'ipertensione e dell'edema associato a insufficienza cardiaca. È caratterizzato dalla sua capacità di inibire il riassorbimento del sodio nel tubulo contorto distale del nefrone, portando a un aumento della produzione di urina e a una diminuzione della pressione sanguigna. Indapamide è noto per la sua emivita relativamente lunga, che consente una somministrazione una volta al giorno, migliorando la compliance del paziente. Il composto è tipicamente somministrato per via orale ed è spesso preferito per i suoi effetti vasodilatatori aggiuntivi, che possono contribuire alle sue proprietà antipertensive. Indapamide si distingue anche per il suo basso potenziale di squilibrio elettrolitico rispetto ai diuretici tiazidici tradizionali, rendendolo una scelta preferita in alcune popolazioni di pazienti. La sua struttura chimica include un gruppo sulfonamide, che è fondamentale per il suo meccanismo d'azione. Come con qualsiasi farmaco, gli effetti collaterali potenziali possono includere vertigini, disturbi elettrolitici e problemi gastrointestinali, richiedendo monitoraggio durante il trattamento.

Formula: C₁₆H₁₆ClN₃O₃S

InChI: InChI=1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)

InChI key: InChIKey=NDDAHWYSQHTHNT-UHFFFAOYSA-N

SMILES: N(C(=O)C1=CC(S(N)(=O)=O)=C(Cl)C=C1)N2C=3C(CC2C)=CC=CC3

Sinonimi:

• 1-(4-Chloro-3-Sulfamoylbenzamido)-2-Methylindoline
• 3-(Aminosulfonyl)-4-Chloro-N-(2,3-Dihydro-2-Methyl-1H-Indol-1-Yl)-Benzamid
• 3-(Aminosulfonyl)-4-Chloro-N-(2,3-Dihydro-2-Methyl-1H-Indol-1-Yl)Benzamide
• 4-Chloro-N-(2-Methyl-1-Indolinyl)-3-Sulfamoyl-Benzamid
• 4-Chloro-N-(2-Methyl-1-Indolinyl)-3-Sulfamoylbenzamide
• 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide
• Arifon
• Bajaten
• Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-
• Benzamide, 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoyl-
• Damide
• Flubest
• Fludex
• Fludin
• Flupamid
• Indaflex
• Indamide
• Indamol
• Indapamid
• Indapamida
• Indapamidum
• Indaparnide
• Ipamix
• Kyd 041
• Lorvas
• Lozol
• N-(4-chloro-3-sulfamoylbenzamido)-2-methylindoline
• N-[4-chloro-3-sulfamoyl-benzamidol]-2-methylindoline
• Natrilix
• Natrix
• Noranat
• Racemic indapamide
• S 1520
• S1520
• Se-1520
• Tandix
• Tertensif
• Veroxil

Indapamide

CAS: 26807-65-8

Formula: C₁₆H₁₆ClN₃O₃S

Purezza: >97.0%(T)(HPLC)

Colore e forma: White to Orange to Green powder to crystal

Peso molecolare: 365.83

Ref: 3B-I0730

Indapamide

CAS: 26807-65-8

Used as an antihypertensive. Diuretic This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part

Formula: C₁₆H₁₆ClN₃O₃S

Peso molecolare: 365.83

Ref: 02-J63846

Indapamide 1.0 mg/ml in Methanol

CAS: 26807-65-8

Colore e forma: Single Solution

Ref: 61-AMP0477.00-01

Indapamide

CAS: 26807-65-8

Colore e forma: Neat

Ref: 61-FOR0477.00

INDAPAMIDE CRS

CAS: 26807-65-8

INDAPAMIDE CRS

Formula: C₁₆H₁₆ClN₃O₃S

Colore e forma: White. Powder.

Peso molecolare: 365.8345

Ref: 41-I0150000

Indapamide

CAS: 26807-65-8

Indapamide

Formula: C₁₆H₁₆ClN₃O₃S

Purezza: 97.8%

Colore e forma: White To Off-White

Peso molecolare: 365.06009

Ref: 47-999

Indapamide

CAS: 26807-65-8

Sulfonamides used as drugs

Formula: C₁₆H₁₆ClN₃O₃S

Colore e forma: White Off-White Powder

Peso molecolare: 365.06009

Ref: 45-1338801

Indapamide

CAS: 26807-65-8

Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.

Formula: C₁₆H₁₆ClN₃O₃S

Purezza: 98.97% - 99.83%

Colore e forma: Solid

Peso molecolare: 365.83

Ref: TM-T1498

Indapamide-13C-d3

CAS: 26807-65-8

Formula: C₁₅₁₃CH₁₃D₃ClN₃O₃S

Colore e forma: White To Off-White Solid

Peso molecolare: 369.84

Ref: 4Z-I-1329

Indapamide

CAS: 26807-65-8

Formula: C₁₆H₁₆ClN₃O₃S

Colore e forma: White To Off-White Solid

Peso molecolare: 365.83

Ref: 4Z-I-1311

Indapamide

CAS: 26807-65-8

Formula: C₁₆H₁₆ClN₃O₃S

Purezza: ≥ 98.0%

Colore e forma: White or off-white powder

Peso molecolare: 365.83

Ref: 7W-GP2749

(RS)-Indapamide

CAS: 26807-65-8

Colore e forma: Neat

Ref: 04-C14288200

Indapamide

Prodotto controllato

CAS: 26807-65-8, 63968-75-2

Formula: C₁₆H₁₄ClN₃O₃S

Colore e forma: Neat

Peso molecolare: 363.82

Ref: 86-MM0477.00

Indapamide RS

CAS: 26807-65-8

Colore e forma: White Solid Crystalline Powder

Ref: 2K-1017500021

rac Indapamide

CAS: 26807-65-8

Applications Used as an antihypertensive. Diuretic.
References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),

Formula: C₁₆H₁₆ClN₃O₃S

Colore e forma: White To Off-White

Peso molecolare: 365.83

Ref: TR-I500100

Indapamide - Bio-X ™

Prodotto controllato

CAS: 26807-65-8

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₆H₁₆ClN₃O₃S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 365.84 g/mol

Ref: 3D-BI300090

Indapamide

Prodotto controllato

CAS: 26807-65-8

Indapamide is an antihypertensive drug that inhibits the activity of the enzyme carbonic anhydrase, which is involved in the conversion of carbon dioxide to bicarbonate. It is used to treat high blood pressure and congestive heart failure. Indapamide has been shown to be effective in reducing oxidative injury to red blood cells and preventing cardiovascular events such as stroke and heart attack. Indapamide also has a long-term efficacy with no withdrawal symptoms or rebound hypertension when it is discontinued.

Formula: C₁₆H₁₆ClN₃O₃S

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 365.84 g/mol

Ref: 3D-FI01202

Indapamide

CAS: 26807-65-8

Formula: C₁₆H₁₆ClN₃O₃S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 365.8345

Ref: IN-DA003AXB