CAS 27244-64-0

6-Idrossi-L-DOPA

Descrizione:

6-Idrossi-L-DOPA, con il numero CAS 27244-64-0, è un composto chimico che è un derivato della L-DOPA, un precursore aminoacidico della dopamina. Questo composto presenta un gruppo idrossile nella posizione 6 dell'anello aromatico, che lo distingue dal suo composto genitore. È tipicamente caratterizzato dal suo ruolo nelle vie biochimiche, in particolare nella sintesi dei neurotrasmettitori. 6-Idrossi-L-DOPA è di interesse nella neurofarmacologia e nella ricerca relativa alla malattia di Parkinson, poiché può influenzare l'attività dopaminergica. Il composto è generalmente solubile in acqua ed espone proprietà tipiche dei composti fenolici, come la potenziale attività antiossidante. La sua stabilità e reattività possono essere influenzate da fattori ambientali come pH e temperatura. Come molte sostanze biochimiche, è importante maneggiare 6-Idrossi-L-DOPA con cura in ambienti di laboratorio, seguendo i protocolli di sicurezza per mitigare eventuali rischi potenziali associati al suo uso.

Formula: C₉H₁₁NO₅

InChI: InChI=1S/C9H11NO5/c10-5(9(14)15)1-4-2-7(12)8(13)3-6(4)11/h2-3,5,11-13H,1,10H2,(H,14,15)/t5-/m0/s1

InChI key: InChIKey=YLKRUSPZOTYMAT-YFKPBYRVSA-N

SMILES: C([C@@H](C(O)=O)N)C1=C(O)C=C(O)C(O)=C1

Sinonimi:

• (2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid
• 2,4,5-Trihydroxy-<span class="text-smallcaps">L</span>-phenylalanine
• 2,4,5-Trihydroxy-L-phenylalanine
• 2,4,5-Trihydroxyphenylalanine
• 2,5-Dihydroxy-<span class="text-smallcaps">L</span>-tyrosine
• 2,5-Dihydroxy-L-tyrosine
• 3-(3,4,6-Trihydroxyphenyl)-<span class="text-smallcaps">L</span>-alanine
• 3-(3,4,6-Trihydroxyphenyl)-L-alanine
• 6-Hydroxy-<span class="text-smallcaps">L</span>-DOPA
• 6-Hydroxy-L-DOPA
• <span class="text-smallcaps">L</span>-6-Hydroxydopa
• <span class="text-smallcaps">L</span>-Tyrosine, 2,5-dihydroxy-
• Alanine, 3-(2,4,5-trihydroxyphenyl)-, <span class="text-smallcaps">L</span>-
• Alanine,3-(2,4,5-trihydroxyphenyl)-, L- (8CI)
• Hydroxy-<span class="text-smallcaps">L</span>-dopa
• Hydroxy-L-dopa
• L-6-Hydroxydopa
• Topa
• L-Tyrosine, 2,5-dihydroxy-

Levodopa EP Impurity A

CAS: 27244-64-0

Formula: C₉H₁₁NO₅

Peso molecolare: 213.19

Ref: ST-EA-CP-L16001

Levodopa Related Compound A (3-(2,4,5-Trihydroxyphenyl)-L-alanine)

CAS: 27244-64-0

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₉H₁₁NO₅

Colore e forma: Brown Grey Powder

Peso molecolare: 213.06372

Ref: 45-1361010

2,5-Dihydroxy-L-tyrosine

CAS: 27244-64-0

Formula: C₉H₁₁NO₅

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 213.1873

Ref: IN-DA00C28S

(S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid

CAS: 27244-64-0

(S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid

Purezza: 97%

Peso molecolare: 213.19g/mol

Ref: 54-OR1074264

Levodopa EP Impurity A (Levodopa USP Related Compound A, 6-Hydroxy L-DOPA)

CAS: 27244-64-0

Formula: C₉H₁₁NO₅

Peso molecolare: 213.19

Ref: 4Z-D-3229

6-Hydroxy-L-DOPA

Prodotto controllato

CAS: 27244-64-0

Impurity Levodopa EP Impurity A; Levodopa USP Related Compound A
Stability Hygroscopic
Applications 6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
References Jaim-Etcheverry, G. et al.: Brain Res., 100, 699 (1975); Kostrzewa, R.M. et al.: Amino Acids, 14, 175 (1998); Berthet, A. et al.: J. Neurosci., 29, 4829 (2009);

Formula: C₉H₁₁NO₅

Colore e forma: Brown To Black

Peso molecolare: 213.19

Ref: TR-H941725

6-Hydroxy-L-DOPA

CAS: 27244-64-0

6-Hydroxy-L-DOPA is a quinone, which is the cofactor of tetracycline resistance. It is also a component of tricyclic antidepressant drugs, and has been shown to have neuroprotective effects. 6-Hydroxy-L-DOPA binds to the polymerase chain reaction (PCR) by way of a signal peptide sequence and can be used as a pharmacological agent in patients with oxidative injury. 6-Hydoxy-L-DOPA is bound in the form of an oxidized quinone ring, which coordinates with copper ions via two oxygen atoms and two nitrogen atoms. The structure has been determined using x-ray crystal structures. This compound has an oxidase activity that generates hydrogen peroxide from hydrogen peroxide and water, which results in oxidative injury.

Formula: C₉H₁₁NO₅

Purezza: Min. 95%

Peso molecolare: 213.19 g/mol

Ref: 3D-FH24378

6-Hydroxy-L-DOPA

CAS: 27244-64-0

Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot

Formula: C₉H₁₁NO₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 213.19

Ref: TM-T20396