CAS 27469-60-9

1-Bis(4-fluorofenil)metil piperazina

Descrizione:

1-Bis(4-fluorofenil)metil piperazina, con il numero CAS 27469-60-9, è un composto chimico caratterizzato dal suo nucleo di piperazina, che è un'ammina eterociclica a sei membri. Questo composto presenta due gruppi para-fluorofenile attaccati a un anello centrale di piperazina, contribuendo alle sue proprietà uniche. È tipicamente un solido a temperatura ambiente ed espone una solubilità moderata in solventi organici, influenzata dalla presenza degli atomi di fluoro che ne migliorano la lipofilia. I sostituenti di fluoro possono anche influenzare le proprietà elettroniche del composto, potenzialmente influenzando la sua reattività e interazione con obiettivi biologici. 1-Bis(4-fluorofenil)metil piperazina potrebbe essere di interesse nella chimica medicinale, in particolare nello sviluppo di farmaci, grazie alle sue caratteristiche strutturali che possono modulare l'attività biologica. Inoltre, la sua sintesi e caratterizzazione coinvolgono tecniche standard di chimica organica e potrebbe essere studiato per le sue potenziali applicazioni in vari campi, incluso il design di farmaci e la scienza dei materiali.

Formula: C₁₇H₁₈F₂N₂

InChI: InChI=1/C17H18F2N2/c18-15-5-1-13(2-6-15)17(21-11-9-20-10-12-21)14-3-7-16(19)8-4-14/h1-8,17,20H,9-12H2/p+2

InChI key: InChIKey=TTXIFFYPVGWLSE-UHFFFAOYSA-N

SMILES: C(C1=CC=C(F)C=C1)(C2=CC=C(F)C=C2)N3CCNCC3

Sinonimi:

• 1-(4,4'-Difluorobenzhydryl)Piperazine
• 1-(Di-p-fluorobenzhydryl)piperazine
• 1-[Bis(4-Fluorophenyl)Methyl]Piperazinediium
• 4,4'-Difluorobenzhydrylpiperazine
• 4-[Bis(4-fluorophenyl)methyl]piperazine
• Di(4-fluorophenyl)methyl piperazine
• N-(4,4-Difluorobenzhydryl)piperazine
• N-(Bis(4-fluorophenyl)methyl)piperazine
• Piperazine, 1-[bis(4-fluorophenyl)methyl]-
• Piperazine, 1-[bis(p-fluorophenyl)methyl]-
• R 19352
• T 841
• 1-[Bis(4-fluorophenyl)methyl]piperazine
• 1-[Bis(4-fluorophenyl)methyl]piperazine
• 1-(bis(4-fluorophenyl)methyl) piperazine
• 1-(4,4'-Diflurobenzhydryl)piperazine
• 1-(4,4'-DIFLUORODIPHENYLMETHYL)PIPERAZINE
• 1-(4,4'-Difluorobenzhydryl)piperazine 97%
• 1-[BIS(4-FLUOROPHENYL)METHYL]PIPERAZINE HYDROGEN CHLORIDE
• N-(4,4"-DIFLUOROBENZYLHYDRYL) PIPERAZINE
• 1-BIS (P-FLUOROPHENYL) METHYL PIPERAZINE
• 4,4-Difluorobenzhydrolpiperazine
• 1-[BIS(4-FLUOROPHENZYL)METHYL]PIPERAZINE
• 1-BIS(4-FLUOROPHENYL)METHYL PIPERAZINE 97%
• 1-(4,4'-Difluorobenzhydryl)piperazine97%
• TIMTEC-BB SBB002996
• 1-[DI(4-FLUOROPHENYL)METHYL]PIPERAZINE
• 1-[Bis(4-Fluorophenyl)methyl]p
• 4,4'-DIFLUOROBENZHYDRYL PIPERAZINE

1-[Bis(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

Formula: C₁₇H₁₈F₂N₂

Purezza: >97.0%(GC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 288.34

Ref: 3B-B2764

1-Bis(4-fluorophenyl)methyl piperazine

CAS: 27469-60-9

Formula: C₁₇H₁₈F₂N₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 288.3350

Ref: IN-DA003KF5

Flunarizine EP Impurity A

CAS: 27469-60-9

Formula: C₁₇H₁₈F₂N₂

Colore e forma: White To Off-White Solid

Peso molecolare: 288.34

Ref: 4Z-F-084009

1-[Bis(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

1-[Bis(4-fluorophenyl)methyl]piperazine

Formula: C₁₇H₁₈F₂N₂

Purezza: 98%

Colore e forma: white to off-white powder

Peso molecolare: 288.34g/mol

Ref: 54-PC5636

Flunarizine EP Impurity A

Prodotto controllato

CAS: 27469-60-9

Formula: C₁₇H₁₈F₂N₂

Colore e forma: Neat

Peso molecolare: 288.34

Ref: 86-MM0175.04

1-Bis(4-fluorophenyl)methyl Piperazine

Prodotto controllato

CAS: 27469-60-9

Impurity Flumazenil EP Impurity A
Stability Hygroscopic
Applications 1-Bis(4-fluorophenyl)methyl Piperazine (Flumazenil EP Impurity A) is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, Y. et al.: Bioorg. Med. Chem., 22, 2409 (2014); Gurdal, E. et al.: J. Enz. Inhib. Med. Chem., 29, 205 (2014);

Formula: C₁₇H₁₈F₂N₂

Colore e forma: White To Light Yellow

Peso molecolare: 288.34

Ref: TR-B434875

1-[Bis-(4-fluorophenyl)methyl]piperazine

CAS: 27469-60-9

Formula: C₁₇H₁₈F₂N₂

Purezza: 97.0%

Colore e forma: Solid

Peso molecolare: 288.342

Ref: 10-F019234

1-Bis(4-fluorophenyl)methyl Piperazine-d8

Prodotto controllato

CAS: 27469-60-9

Applications 1-Bis(4-fluorophenyl)methyl Piperzaine-d8 is a labelled analogue of 1-Bis(4-fluorophenyl)methyl Piperzaine (B434875), which is a chemical reagent used in the synthesis of novel tubulin polymerization inhibitors. Also used in the synthesis of novel benzhydrylpiperazine carboxamide derivatives. Impurity of F455200. It is also an intermediate in synthesizing Flunarizine-d8 Dihydrochloride (F455202), which is a calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, Y. et al.: Bioorg. Med. Chem., 22, 2409 (2014); Gurdal, E. et al.: J. Enz. Inhib. Med. Chem., 29, 205 (2014); Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975); Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979); Nihard, P., et al.: Angiology, 33, 37 (1982); Holmes, B., et al.: Drugs, 27, 6 (1984);

Formula: C₁₇H₁₀D₈F₂N₂

Colore e forma: Neat

Peso molecolare: 296.38

Ref: TR-B434877

Flunarizine EP Impurity A

CAS: 27469-60-9

Formula: C₁₇H₁₈F₂N₂

Peso molecolare: 288.34

Ref: ST-EA-CP-F140003

1-(4,4'-Difluorobenzhydry)piperazine

CAS: 27469-60-9

1-(4,4'-Difluorobenzhydry)piperazine (1-DFBP) is a potential antitumor agent that has been shown to inhibit the growth of leukemia cells. It may be an inhibitor of apoptotic cell death, as it has been shown to induce hydrogen bond formation with coumarin derivatives. 1-DFBP has also been shown to have inhibitory activities against leukemia HL-60 cells, and is a competitive inhibitor of cinnarizine. The catalytic mechanism for 1-DFBP is not known, although kinetic data suggest that it involves hydrogen bonding and/or pi stacking interactions.

Formula: C₁₇H₁₈F₂N₂

Purezza: Min. 95%

Peso molecolare: 288.34 g/mol

Ref: 3D-FD55069