CAS 274693-27-5

(1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorofenil) ciclopropilamino]-5-(propilsulfanil)-3H-[1,2,3]triazolo[4,5-d]pirimidin-3-il]-5-(2-idrossietossi) ciclopentano-1,2-diolo

Descrizione:

La sostanza chimica con il nome "(1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorofenil) ciclopropilamino]-5-(propilsulfanil)-3H-[1,2,3]triazolo[4,5-d]pirimidin-3-il]-5-(2-idrossietossi) ciclopentano-1,2-diolo" e numero CAS "274693-27-5" è un composto organico complesso caratterizzato dalla sua struttura multiciclica e da vari gruppi funzionali. Presenta un nucleo di ciclopentano con più stereocentri, indicando chiralità, che può influenzare la sua attività biologica e le interazioni. La presenza di un gruppo triazolopirimidinico suggerisce potenziali proprietà farmacologiche, poiché questo scaffold è spesso associato a vari effetti terapeutici. Inoltre, i gruppi difluorofenile e propilsulfanile possono migliorare la lipofilia e modulare l'affinità di legame del composto con obiettivi biologici. I gruppi idrossilici contribuiscono alla sua polarità e solubilità in ambienti acquosi, il che può influenzare la sua biodisponibilità. In generale, la struttura intricata e la diversità funzionale di questo composto suggeriscono potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di nuovi terapeutici.

Formula: C₂₃H₂₈F₂N₆O₄S

InChI: InChI=1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1

InChI key: InChIKey=OEKWJQXRCDYSHL-FNOIDJSQSA-N

SMILES: N(C1=C2C(N(N=N2)[C@@H]3C[C@H](OCCO)[C@@H](O)[C@H]3O)=NC(SCCC)=N1)[C@H]4[C@@H](C4)C5=CC(F)=C(F)C=C5

Sinonimi:

• (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
• 1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-
• Ar-C 126532Xx
• Ar-C126532
• Azd 6140
• Azd6140
• Brilinta
• Brilique
• Possia
• Ticagrelor
• Triafluocyl
• (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-D1,2-Cyclopentanediolifluorophenyl)cyclopropyl]aMino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyriMidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
• Ticagrelor(AR-C 126532XX
• Unii-glh0314rvc
• (1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• Tecagrelor
• 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]aMino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyriMidin-3-yl]-5-(2-hydroxyethoxy)-,(1S,2S,3R,5S)-
• Ticagrelor (AZD6140)
• (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylaMino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• Ticarelor
• Ticargrelor

TICAGRELOR CRS

CAS: 274693-27-5

TICAGRELOR CRS

Ref: 41-Y0002222

Ticagrelor

CAS: 274693-27-5

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₂₃H₂₈F₂N₆O₄S

Colore e forma: White Off-White Pink Powder

Peso molecolare: 522.18608

Ref: 45-1667177

(1S,2S,3R,5S)-3-(7-(((1R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3h-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

CAS: 274693-27-5

Formula: C₂₃H₂₈F₂N₆O₄S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 522.5680

Ref: IN-DA00I57D

Ticagrelor

CAS: 274693-27-5

Ticagrelor (AR-C 126532XX), produced by AstraZeneca, is an inhibitor of platelet aggregation.

Formula: C₂₃H₂₈F₂N₆O₄S

Purezza: 98.08% - 99.77%

Colore e forma: Solid

Peso molecolare: 522.57

Ref: TM-T0179

Ticagrelor

CAS: 274693-27-5

Formula: C₂₃H₂₈F₂N₆O₄S

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 522.57

Ref: 7W-GP6595

Ticagrelor

CAS: 274693-27-5

Ticagrelor

Purezza: 98%

Peso molecolare: 522.58g/mol

Ref: 54-PC109241

Ticagrelor

CAS: 274693-27-5

Ticagrelor

Purezza: ≥98%

Peso molecolare: 522.57g/mol

Ref: 54-BUP17709

Ticagrelor

CAS: 274693-27-5

Formula: C₂₃H₂₈F₂N₆O₄S

Colore e forma: White To Off-White Solid

Peso molecolare: 522.57

Ref: 4Z-T-811

Ticagrelor

CAS: 274693-27-5

Formula: C₂₃H₂₈F₂N₆O₄S

Purezza: >98.0%(HPLC)(qNMR)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 522.57

Ref: 3B-T4282

Ticagrelor

Prodotto controllato

CAS: 274693-27-5

Formula: C₂₃H₂₈F₂N₆O₄S

Colore e forma: Neat

Peso molecolare: 522.57

Ref: 86-MM3615.00

Ticagrelor Impurity 18

CAS: 274693-27-5

Formula: C₇H₉Cl₂N₃O₂S

Colore e forma: White To Off-White Solid

Peso molecolare: 270.13

Ref: 4Z-T-81136

Ticagrelor

Prodotto controllato

CAS: 274693-27-5

Stability Hygroscopic
Applications Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),

Formula: C₂₃H₂₈F₂N₆O₄S

Colore e forma: White

Peso molecolare: 522.57

Ref: TR-T437700

Ticagrelor

CAS: 274693-27-5

Reversible P2Y12 receptor antagonist; ADP-induced platelet aggregation blocker

Formula: C₂₃H₂₈F₂N₆O₄S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 522.57 g/mol

Ref: 3D-FD29104

Ticagrelor - Bio-X ™

CAS: 274693-27-5

Ticagrelor is a P2Y12 receptor antagonist that has been shown to reduce the risk of myocardial infarction. It inhibits the formation of thromboses. Ticagrelor binds to the adenosine diphosphate (ADP) site on the platelet P2Y receptor and prevents ADP from activating this receptor. It is used for the prevention of myocardial infarctions, strokes and cardiovascular disease.

Formula: C₂₃H₂₈F₂N₆O₄S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 522.57 g/mol

Ref: 3D-BT164470

TICAGRELOR

CAS: 274693-27-5

Purezza: 98%

Peso molecolare: 522.5700073

Ref: 10-F793231

ent-Ticagrelor-d7

Prodotto controllato

CAS: 274693-27-5

Formula: C₂₃H₂₁D₇F₂N₆O₄S

Colore e forma: Neat

Peso molecolare: 260.284

Ref: TR-T437712