CAS 2752-64-9

Aconitano-3,8,13,14,15-pentolo, 1,6,16-trimetossi-4-(metossimetil)-20-metil-, 8-acetato 14-benzoato, (1α,3α,6α,14α,15α,16β)-

Descrizione:

Aconitano-3,8,13,14,15-pentolo, 1,6,16-trimetossido-4-(metossimetile)-20-metile-, 8-acetato 14-benzoato, con il numero CAS 2752-64-9, è un composto organico complesso appartenente alla classe degli alcaloidi derivati dalle specie di Aconitum. Questa sostanza presenta più gruppi funzionali, inclusi gruppi metossido e acetato, che contribuiscono alla sua reattività chimica e potenziale attività biologica. La presenza di più gruppi idrossilici indica che potrebbe esibire capacità di legame idrogeno, influenzando la sua solubilità e interazione con i sistemi biologici. I derivati dell'aconitano sono spesso studiati per le loro proprietà farmacologiche, inclusi potenziali effetti analgesici e anti-infiammatori. Tuttavia, a causa della tossicità associata a molti alcaloidi di Aconitum, è essenziale una manipolazione attenta e una comprensione approfondita delle sue implicazioni biologiche. La complessità strutturale di questo composto suggerisce che potrebbe avere proprietà stereochimiche uniche, che potrebbero influenzare la sua interazione con obiettivi biologici. Ulteriori ricerche sono necessarie per chiarire completamente le sue proprietà e potenziali applicazioni in chimica medicinale.

Formula: C₃₃H₄₅NO₁₁

InChI: InChI=1/C33H45NO11/c1-16(35)45-33-21-18(13-31(39,28(43-6)26(33)37)27(21)44-29(38)17-10-8-7-9-11-17)32-20(41-4)12-19(36)30(15-40-3)14-34(2)25(32)22(33)23(42-5)24(30)32/h7-11,18-28,36-37,39H,12-15H2,1-6H3/t18-,19-,20+,21-,22+,23+,24-,25?,26+,27-,28+,30+,31-,32+,33-/m1/s1

InChI key: InChIKey=XUHJBXVYNBQQBD-GQPWXMLZSA-N

SMILES: O(C)[C@@H]1[C@@]23[C@]4([C@](COC)(CN(C)[C@@]2([C@]([C@@H]4OC)([C@]5(OC(C)=O)[C@@]6([C@]3(C[C@@](O)([C@@H]6OC(=O)C7=CC=CC=C7)[C@@H](OC)[C@@H]5O)[H])[H])[H])[H])[C@H](O)C1)[H]

Sinonimi:

• (16Beta)-8-(Acetyloxy)-3,13,15-Trihydroxy-1,6,16-Trimethoxy-4-(Methoxymethyl)-20-Methylaconitan-14-Yl Benzoate
• (3Alpha,6Alpha,14Alpha,15Alpha,16Beta)-8-(Acetyloxy)-3,13,15-Trihydroxy-1,6,16-Trimethoxy-4-(Methoxymethyl)-20-Methylaconitan-14-Yl Benzoate
• 2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-3,8,13,14,15-pentol deriv.
• 8-(Acetyloxy)-3,13,15-Trihydroxy-1,6,16-Trimethoxy-4-(Methoxymethyl)-20-Methylaconitan-14-Yl Benzoate
• Mesaconitine
• NSC 77210
• Aconitane-3,8,13,14,15-pentol, 1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-, 8-acetate 14-benzoate, (1α,3α,6α,14α,15α,16β)-
• Japaconitine B
• Mesaconitine Solution, 100ppm
• Aconitane-3,8,13,14,15-pentol, 1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-
• Mesaaconitine
• 1α,6α,16β-Trimethoxy-4-methoxymethyl-20-methylaconitane-3α,8,13,14α,15α-pentol 8-acetate 14-benzoate
• MESACONITINE, 98% (PRIMARY STANDARD)
• Mesaconitine, 98%, from Aconitum carmichaeli Debeaux
• MESACONITINE(SH)
• 4-(Methoxymethyl)-20-methyl-1α,6α,16β-trimethoxyaconitane-3α,8,13,14α,15α-pentol 8-acetate 14-benzoate
• (1α,3α,6α,14α,15α,16β)-1,6,16-TriMethoxy-4-(MethoxyMethyl)-20-Methyl-aconitane-3,8,13,14,15-pentol 8-Acetate 14-Benzoate
• MESACONITINE(AS)
• (1a,3a,6a,14a,15a,16β)-1,6,16-Trimethoxy-4-(methoxymethyl)-20-methyl-aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate
• N-Desethyl-N-Methylaconitine
• Mesaconitine USP/EP/BP
• (1-alpha,3-alpha,6-alpha,14-alpha,15-alpha,16-beta)-8-acetate14-benzoat
• Japaconitine A

Aconitane-3,8,13,14,15-pentol,1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-, 8-acetate14-benzoate, (1a,3a,6a,14a,15a,16b)-

CAS: 2752-64-9

Formula: C₃₃H₄₅NO₁₁

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 631.7105

Ref: IN-DA00IKLE

Mesaconitine

CAS: 2752-64-9

Mesaconitine

Purezza: ≥95%

Peso molecolare: 631.71g/mol

Ref: 54-BUP00186

Mesaconitine

CAS: 2752-64-9

Formula: C₃₃H₄₅NO₁₁

Peso molecolare: 631.71

Ref: 7W-GP3472

Mesaconitine

CAS: 2752-64-9

Formula: C₃₃H₄₅NO₁₁

Purezza: >95.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 631.72

Ref: 3B-M3404

Mesaconitine

CAS: 2752-64-9

Mesaconitine increases the [Ca2+]i level in endothelial cells by influx of Ca2+ from extracellular spaces, suggests that mesaconitine-induced Ca2+ influx and activation of nitric-oxide synthase in endothelial cells and, thus, induced vasorelaxation in rat aorta.

Formula: C₃₃H₄₅NO₁₁

Purezza: 95%~99%

Colore e forma: White powder

Peso molecolare: 631.719

Ref: BP-BP0935

Mesaconitine

CAS: 2752-64-9

Mesaconitine: anti-inflammatory, relieves pain by boosting cAMP and central β-adrenergic system.

Formula: C₃₃H₄₅NO₁₁

Purezza: 97.45% - 98.98%

Colore e forma: Solid

Peso molecolare: 631.71

Ref: TM-T6S0627

Mesaconitine

CAS: 2752-64-9

Natural alkaloid

Formula: C₃₃H₄₅NO₁₁

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 631.72

Ref: 5G-89731

Mesaconitine

Prodotto controllato

CAS: 2752-64-9

Applications An Aconitine (A189875) analog. Aconitine alkaloid pharmacokinetic analgesic. A highly poisonous, neurotoxic alkaloid.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010), Yan, G., et al.: J. Pharm. Biomed. Anal., 53, 421 (2010),

Formula: C₃₃H₄₅NO₁₁

Colore e forma: Neat

Peso molecolare: 631.71

Ref: TR-M257900

Mesaconitine

CAS: 2752-64-9

Mesaconitine is a highly toxic natural diterpenoid steroid alkaloid found in plants of the Aconitum genre. In 2020, NMR spectroscopy combined with X-ray crystallography have shown an unusual twisted-boat conformation of the mesaconitine molecule.

Formula: C₃₃H₄₅NO₁₁

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 631.71 g/mol

Ref: 3D-FM25110