CAS 2757498-74-9

ER covalent antagonist-1

CAS: 2757498-74-9

ER covalent antagonist-1 (Compound 39D) acts as an antagonist of the estrogen receptor α (ERα). This compound inhibits the proliferation of ERα-positive MCF-7 cells with an IC50 of 0.98 μM, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. Additionally, ER covalent antagonist-1 demonstrates antitumor activity in mouse models.

Formula: C₃₃H₃₂N₂O₅S

Colore e forma: Solid

Peso molecolare: 568.683

Ref: TM-T204764