CAS 284035-33-2

2-cloro-6-[(2R)-3-[[1,1-dimetil-2-(2-naftalenil)etil]amino]-2-idrossipropossi]benzonitrile

Descrizione:

2-cloro-6-[(2R)-3-[[1,1-dimetil-2-(2-naftalenil)etil]amino]-2-idrossipropossi]benzonitrile, con numero CAS 284035-33-2, è un composto organico sintetico caratterizzato dalla sua struttura complessa, che include un gruppo cloro, un moiety di benzonitrile e una catena laterale di idrossipropossido. Questo composto è tipicamente classificato come un intermedio farmaceutico o ingrediente attivo, spesso associato a specifiche applicazioni terapeutiche. La sua struttura molecolare suggerisce potenziali interazioni con bersagli biologici, in particolare nel contesto del legame ai recettori o dell'inibizione degli enzimi. La presenza dell'anello naftalenico indica caratteristiche idrofobiche, che possono influenzare la sua solubilità e biodisponibilità. Inoltre, la chiralità del composto, indicata dalla configurazione (2R), suggerisce che potrebbe presentare proprietà stereoselettive nei sistemi biologici. In generale, le caratteristiche di questo composto, inclusi i suoi gruppi funzionali e la stereochimica, contribuiscono alla sua potenziale efficacia e profilo di sicurezza nella chimica medicinale.

Formula: C₂₄H₂₅ClN₂O₂

InChI: InChI=1/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1

InChI key: InChIKey=PZUJQWHTIRWCID-HXUWFJFHSA-N

SMILES: C(C(NC[C@H](COC1=C(C#N)C(Cl)=CC=C1)O)(C)C)C2=CC3=C(C=C2)C=CC=C3

Sinonimi:

• 2-Chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
• 2-Chloro-6-{[(2R)-2-hydroxy-3-{[2-methyl-1-(2-naphthyl)propan-2-yl]amino}propyl]oxy}benzonitrile
• 2-chloro-6-({(2R)-3-[(1,1-dimethyl-2-naphthalen-2-ylethyl)amino]-2-hydroxypropyl}oxy)benzonitrile
• 2-chloro-6-{[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propyl]oxy}benzonitrile
• Benzonitrile, 2-chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-
• Nps 2143
• Sb 262470
• Sb 262470A
• benzonitrile, 2-chloro-6-[[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropyl]oxy]-
• 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]benzonitrile
• NPS 2143 USP/EP/BP
• SB262470
• SB-262470(NPS-2143)
• NPS-2143(SB 262470A )
• 2-Chloro-6-[3-[1, 1-dimethyl-2-(2-naphthyl)ethylamino]-2(R)-hydroxypropoxy]benzonitrile(NPS 2143)
• CS-1600
• NPS-2143 (SB-262470)
• NPS 2143;SB 262470A;NPS2143;SB262470
• 2-Chloro-6-[3-[1, 1-diMethyl-2-(2-naphthyl)ethylaMino]-2(R)-hydroxypropoxy]benzonitrile
• 2-Chloro-6-[3-[1, 1-dimethyl-2-(2-naphthyl)ethylamino]-2(R)-hydroxypropoxy]benzonitrile(NPS 2
• 2-chloro-6-[(2R)-3-[[1
• NPS-2143 base
• 1-diMethyl-2-(2-naphthalenyl)ethyl]aMino]-2-hydroxypropoxy]-
• (R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
• NPS 2143 hydrochloride(SB-262470)
• NPS 2143; SB 262470A ; NPS2143
• NPS 2143, SB262470 hydrochloride
• NPS-2143;NPS 2143; SB 262470A; NPS2143
• CS-276

2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]benzonitrile

CAS: 284035-33-2

Formula: C₂₄H₂₅ClN₂O₂

Purezza: 98%

Peso molecolare: 408.9205

Ref: IN-DA007KOE

NPS-2143

CAS: 284035-33-2

NPS-2143

Purezza: ≥98%

Peso molecolare: 408.92g/mol

Ref: 54-BUP10169

NPS-2143

CAS: 284035-33-2

NPS-2143 is a small molecule that enhances the mitochondrial membrane potential by regulating intracellular calcium levels. It also prevents the loss of energy metabolism and pathogenic mechanisms of cells. NPS-2143 is a competitive antagonist to the calcium-sensing receptor, which is responsible for sensing extracellular and cytosolic calcium levels. This drug has been shown to inhibit leukocyte recruitment and inflammation in the lungs, as well as inhibiting platelet aggregation. NPS-2143 binds to basic proteins and peptide hormones, such as angiotensin II, erythropoietin, follicle stimulating hormone (FSH), luteinizing hormone (LH), insulin, prolactin, growth hormone (GH), parathyroid hormone (PTH), thyroid stimulating hormone (TSH), somatostatin, vasopressin, calcitonin, glucagon, and secretin.

Formula: C₂₄H₂₅ClN₂O₂

Purezza: Min. 95%

Peso molecolare: 408.92 g/mol

Ref: 3D-JLA03533

NPS-2143

CAS: 284035-33-2

NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.

Formula: C₂₄H₂₅ClN₂O₂

Purezza: 99.56%

Colore e forma: Solid

Peso molecolare: 408.92

Ref: TM-T1730