CAS 2873-36-1

L-leucil-L-prolina lattame

Descrizione:

L-leucil-L-prolina lattame, con il numero CAS 2873-36-1, è un derivato di dipeptide ciclico formato dagli aminoacidi leucina e prolina. Questo composto presenta caratteristiche tipiche dei peptidi, inclusa la presenza di un legame ammidico e una struttura di lattama, che contribuisce alla sua stabilità e alle sue uniche proprietà chimiche. La formazione di lattama porta a una struttura ciclica che può influenzare la sua attività biologica e solubilità. L-leucil-L-prolina lattame è spesso studiato per le sue potenziali applicazioni in farmacologia e biochimica, in particolare nel contesto della sintesi di peptidi e del design di farmaci. Le sue caratteristiche strutturali possono conferire interazioni specifiche con bersagli biologici, rendendolo di interesse nella chimica medicinale. Inoltre, la presenza dell'aminoacido a catena ramificata leucina può migliorare le sue caratteristiche idrofobiche, mentre la struttura ciclica unica della prolina può introdurre rigidità conformazionale. In generale, questo composto esemplifica la complessità e la funzionalità dei derivati peptidici nei sistemi chimici e biologici.

Formula: C₁₁H₁₈N₂O₂

InChI: InChI=1/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)/t8-,9-/m0/s1

InChI key: InChIKey=SZJNCZMRZAUNQT-IUCAKERBSA-N

SMILES: O=C1N2[C@](C(=O)N[C@H]1CC(C)C)(CCC2)[H]

Sinonimi:

• (3S,8aS)-3-(2-methylpropyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
• (3S,8aS)-Hexahydro-3-(2-methylpropyl)pyrrolo[1,2-a]pyrazine-1,4-dione
• 3-(2-Methylpropyl)Hexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione
• <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</span>-proline lactam
• <span class="text-smallcaps">L</smallcap>-Leucyl-<smallcap>L</span>-prolyl lactam
• Brn 0085716
• Cyclo(-Leu-Pro)
• Cyclo(<span class="text-smallcaps">L</smallcap>-Leu-<smallcap>L</span>-Pro)
• Cyclo(<span class="text-smallcaps">L</smallcap>-Pro-<smallcap>L</span>-Leu)
• Cyclo(<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-prolyl)
• Cyclo(<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</span>-leucyl)
• Cyclo(Pro-Leu)
• Cyclo(proline-leucine)
• Cyclo-<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</span>-leucine
• Cyclo-L-leu-L-pro
• Gancidin W
• Maculosin 6
• Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-, (3S-trans)-
• Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-3-isobutyl-, stereoisomer
• Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-, (3S,8aS)-
• cis-Cyclo(<span class="text-smallcaps">L</smallcap>-Leu-<smallcap>L</span>-Pro)
• L-Leucyl-L-proline lactam
• (3S-trans)-Hexahydro-3-isobutylpyrrolo(1,2-a)pyrazine-1,4-dione
• 5-24-07-00347 (Beilstein Handbook Reference)
• Cyclo-L-prolyl-L-leucine
• Cyclo(-L-Leu-L-Pro)≥ 99% (TLC)
• gancidinw
• 3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
• (3S,8aS)-2,3,6,7,8,8a-Hexahydro-3-(2-methylpropyl)pyrrolo[1,2-a]pyrazine-1,4-dione
• (3S,8aS)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
• 3-isobutyl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-quinone
• (3S,8aS)-Octahydro-3-(2-methylpropyl)pyrrolo[1,2-a]pyrazine-1,4-dione
• Cyclo(L-prolyl-L-leucyl)
• L-Leucyl-L-prolyl lactaM
• 3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
• Cyclo(L-Pro-L-Leu-)
• Cyclo(L-leucyl-L-prolyl-)
• 4-dione,hexahydro-3-(2-methylpropyl)-2-a)pyrazine-(3s-trans)-pyrrolo(
• Cyclo(L-Pro-D-Leu)
• (3S-trans)-Hexahydro-3-(2-Methylpropyl)-pyrrolo[1,2-a]pyrazine-1,4-dione

Cyclo(-Leu-Pro)

CAS: 2873-36-1

Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry.

Formula: C₁₁H₁₈N₂O₂

Purezza: > 99%

Colore e forma: White Powder

Peso molecolare: 210.28

Ref: 01-4003115

Cyclo(L-Leu-L-Pro)

CAS: 2873-36-1

Cyclo(L-Leu-L-Pro) is a compound from Pseudomonas sesquiterpenes BC42 with antifungal activity that inhibits fungal pathogens.

Formula: C₁₁H₁₈N₂O₂

Purezza: >99.99%

Colore e forma: Solid

Peso molecolare: 210.27

Ref: TM-T125115

Cyclo(-leu-pro)

CAS: 2873-36-1

Formula: C₁₁H₁₈N₂O₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 210.2728

Ref: IN-DA002WA1

Cyclo(-Leu-Pro)

CAS: 2873-36-1

Peso molecolare: 210.27

Ref: 7W-GM1727

Cyclo(L-Leu-L-Pro)

CAS: 2873-36-1

Cyclo(L-Leu-L-Pro)

Purezza: ≥98%

Peso molecolare: 210.27g/mol

Ref: 54-BUP11331

Cyclo(L-Pro-L-Leu)

CAS: 2873-36-1

Formula: C₁₁H₁₈N₂O₂

Purezza: >95.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 210.28

Ref: 3B-C3973

Cyclo(L-leucyl-L-prolyl)

CAS: 2873-36-1

Formula: C₁₁H₁₈N₂O₂

Peso molecolare: 210.28

Ref: 4Z-N-0673

Cyclo(L-leucyl-L-prolyl)-d7

CAS: 2873-36-1

Formula: C₁₁H₁₁D₇N₂O₂

Peso molecolare: 217.32

Ref: 4Z-N-0675

Cyclo(L-prolyl-L-leucyl)

Prodotto controllato

CAS: 2873-36-1

Applications Sorbicillin analog. A bioactive secondary metabolites from terrestrial Streptomyces species TN262.
References Ma, L. et al. : J. Anitibiot. 64, 645 (2011); Elleuch, L. et al.: Appl. Biochem. Biotech. 162, 579 (2010)

Formula: C₁₁H₁₈N₂O₂

Colore e forma: Neat

Peso molecolare: 210.27

Ref: TR-C987660

Cyclo(L-prolyl-L-leucyl)

CAS: 2873-36-1

Cyclo(L-prolyl-L-leucyl) is a cyclic lipopeptide that inhibits the transcription of DNA. It binds to the polymerase chain and blocks the transcription process, which prevents the production of RNA. Cyclo(L-prolyl-L-leucyl) has been shown to have an inhibitory effect on human pathogens such as fungi, protozoa, or bacteria. Cyclo(L-prolyl-L-leucyl) also has anti-cancer properties and is used for cancer treatment. Cyclo(L-prolyl-L-leucyl) is extracted from an acetate extract and purified by chromatography. The purified product is then tested in vitro using assays including magnetic resonance spectroscopy.

Formula: C₁₁H₁₈N₂O₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 210.27 g/mol

Ref: 3D-FC20681

(3S,8aS)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione

CAS: 2873-36-1

Formula: C₁₁H₁₈N₂O₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 210.277

Ref: 10-F463133