CAS 287714-41-4: Rosuvastatina

Descrizione: Rosuvastatina è un agente sintetico riduttore dei lipidi appartenente alla classe delle statine, utilizzato principalmente per gestire l'iperlipidemia e ridurre il rischio di malattie cardiovascolari. La sua formula chimica è C22H28FN3O6S e presenta una struttura distintiva che include un gruppo fluorofenile e un moiety di sulfonamide, contribuendo alla sua potenza. Rosuvastatina agisce inibendo la HMG-CoA reduttasi, un enzima cruciale per la biosintesi del colesterolo nel fegato, abbassando così i livelli di colesterolo LDL (lipoproteine a bassa densità) e trigliceridi, mentre aumenta il colesterolo HDL (lipoproteine ad alta densità). Il farmaco è caratterizzato da un'alta biodisponibilità e una lunga emivita, consentendo una somministrazione una volta al giorno. È generalmente ben tollerato, sebbene gli effetti collaterali potenziali possano includere dolore muscolare, elevazioni degli enzimi epatici e disturbi gastrointestinali. Rosuvastatina è spesso prescritto insieme a modifiche dello stile di vita, come dieta ed esercizio, per migliorare i suoi effetti riduttori del colesterolo. Il suo profilo di efficacia e sicurezza lo rende un farmaco ampiamente utilizzato nella gestione della dislipidemia.

Formula: C₂₂H₂₈FN₃O₆S

InChI: InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1

InChI key: InChIKey=BPRHUIZQVSMCRT-VEUZHWNKSA-N

SMILES: O=C(O)CC(O)CC(O)C=CC=1C(=NC(=NC1C(C)C)N(C)S(=O)(=O)C)C=2C=CC(F)=CC2

Sinonimi:

• (3R,5R,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
• (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid
• (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxy-6-heptenoic acid
• (E)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methylsulfonyl)(methyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, (3R,5S,6E)-
• 7-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-(Methyl-Methylsulfonyl-Amino)-Pyrimidin-5-Yl]-3,5-Dihydroxy-Hept-6-Enoic Acid
• Azd 4522
• Azd4522
• Rosuvastatin Acid
• Rosuvastatin intermediates
• X-Plended
• Zd 4522
• Rosuvastatin

Rosuvastatin Calcium

CAS: 147098-20-2 287714-41-4

• Formula: C₄₄H₅₄CaF₂N₆O₁₂S₂
• Purezza: >95.0%(HPLC)(N)
• Colore e forma: White to Almost white powder to crystal
• Peso molecolare: 1,001.14

6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, (3R,5S,6E)-

CAS: 287714-41-4

• Formula: C₂₂H₂₈FN₃O₆S
• Purezza: 98%
• Colore e forma: Solid
• Peso molecolare: 481.5376

Rosuvastatin-d3 sodium salt

CAS: 287714-41-4

• Formula: C₂₂H₂₄D₃FN₃O₆S·Na
• Colore e forma: Yellow Solid
• Peso molecolare: 483.56 22.99

Rosuvastatin-d4 sodium salt

CAS: 287714-41-4

• Formula: C₂₂H₂₃D₄FN₃O₆S·Na
• Peso molecolare: 484.56 22.99

Rosuvastatin EP Impurity I Calcium Salt

CAS: 287714-41-4

• Formula: C₂₂H₂₇FN₃O₆SCa
• Peso molecolare: 480.54 1/2 40.08

Rosuvastatin

CAS: 287714-41-4

Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. …

• Formula: C₂₂H₂₈FN₃O₆S
• Purezza: 95.24% - 99.8%
• Colore e forma: Solid
• Peso molecolare: 481.54

(3S,5S)-5-((R)-8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate Sodium Salt

CAS: 287714-41-4

Applications (3S,5S)-5-((R)-8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate Sodium Salt is an impurity of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase …

• Formula: C₂₂H₂₇FN₃NaO₆S
• Colore e forma: Neat
• Peso molecolare: 503.519

rac-Rosuvastatin Sodium Salt (Mixture: R700515 and Sodium Salt of R700500)

CAS: 287714-41-4

• Formula: C₂₂H₂₇FN₃NaO₆S
• Colore e forma: Neat
• Peso molecolare: 503.519

rac-Rosuvastatin Sodium Salt (E/Z Mixture)

CAS: 1007871-86-4 287714-41-4

• Formula: C₂₂H₂₇FN₃NaO₆S
• Colore e forma: Neat
• Peso molecolare: 503.52

7,8-Dihydro-rosuvastatin Diisopropylammonium Salt

CAS: 287714-41-4

• Formula: C₂₈H₄₅FN₄O₆S
• Colore e forma: Neat
• Peso molecolare: 584.74

N-Desmethyl N-ethyl Rosuvastatin Sodium Salt

CAS: 287714-41-4

• Formula: C₂₃H₂₉FN₃NaO₆S
• Colore e forma: Neat
• Peso molecolare: 517.546

(3S,5R)-5-((R)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate Sodium Salt

CAS: 287714-41-4

• Formula: C₂₂H₂₇FN₃NaO₆S
• Colore e forma: Neat
• Peso molecolare: 503.519

(3S,5S)-5-((S)-8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate Sodium Salt

CAS: 287714-41-4

Applications (3S,5S)-5-((S)-8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate Sodium Salt is an impurity of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase …

• Formula: C₂₂H₂₇FN₃NaO₆S
• Colore e forma: Neat
• Peso molecolare: 503.519

Rosuvastatin

CAS: 287714-41-4

Please enquire for more information about Rosuvastatin including the price, delivery time and more detailed …

• Formula: C₂₂H₂₈FN₃O₆S
• Purezza: Min. 95%
• Peso molecolare: 481.54 g/mol