CAS 28920-43-6

Cloroformiato di 9-fluorenilmetile

Descrizione:

Cloroformiato di 9-fluorenilmetile, con il numero CAS 28920-43-6, è un composto organico comunemente utilizzato come reagente nella sintesi organica, in particolare nel campo della chimica dei peptidi e degli aminoacidi. Presenta un gruppo fluorenilmetile, che ne migliora la reattività e la solubilità nei solventi organici. Il composto è caratterizzato dal suo gruppo funzionale cloroformiato, noto per la sua capacità di formare carbammati in reazione con ammine. Questa proprietà lo rende prezioso per proteggere i gruppi amminici durante i processi di sintesi a più fasi. Cloroformiato di 9-fluorenilmetile è tipicamente un liquido incolore o giallo pallido, ed è sensibile all'umidità e all'aria, richiedendo una manipolazione e una conservazione attente in condizioni inerti. La sua reattività può essere attribuita alla natura elettrofila del carbonio carbonilico nel gruppo cloroformiato, permettendogli di partecipare a reazioni di sostituzione nucleofila. In generale, questo composto è uno strumento importante nella chimica organica sintetica, in particolare per la protezione e l'attivazione dei gruppi funzionali.

Formula: C₁₅H₁₁ClO₂

InChI: InChI=1S/C15H11ClO2/c16-15(17)18-9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14H,9H2

InChI key: InChIKey=IRXSLJNXXZKURP-UHFFFAOYSA-N

SMILES: C(OC(Cl)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (9H-Fluoren-9-ylmethoxy)carbonyl chloride
• 9-Fluorenylmethoxycarbonyl
• 9-Fluorenylmethoxycarbonyl chloride
• 9-Fluorenylmethyl chlorocarbonate
• 9-Fluorenylmethyloxycarbonylchloride
• 9H-Fluoren-9-ylmethylchlorformiat
• 9H-fluoren-9-ylmethyl carbonochloridate
• 9H-fluoren-9-ylmethyl chloroformate
• AminoTag
• Carbonic acid, monoanhydride with carbonochloridic acid, 9H-fluoren-9-ylmethyl ester
• Carbonochloridic acid, 9H-fluoren-9-ylmethyl ester
• Chloroformate, (9-Fluorenylmethyl)
• Chloroformiate de 9H-fluoren-9-ylmethyle
• Chloroformic acid 9-fluorenylmethyl ester
• FMOC-chloride
• Fluorene-9-methanol, chloroformate
• Fluorenylmethyl chloroformate
• Fmoc-Cl
• FmocCl
• Formic acid, chloro-, fluoren-9-ylmethyl ester
• chloroformiate de 9H-fluorene-9-ylmethyle
• cloroformiato de 9H-fluoren-9-ilmetilo

9-Fluorenylmethyl Chloroformate [N-Protecting Agent for Peptides Research]

CAS: 28920-43-6

Formula: C₁₅H₁₁ClO₂

Purezza: >97.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystaline

Peso molecolare: 258.70

Ref: 3B-F0197

9-Fluorenylmethyl chloroformate, 98+%

CAS: 28920-43-6

Base sensitive amino protecting group for solid-phase peptide synthesis9-Fluorenylmethyl chloroformate is used in capillary electrophoresis. It acts as a reagent in the precolumn derivatization of amines for HPLC and fluorescent detection. Further, it is used for derivatizing amino acids for HPLC an

Formula: C₁₅H₁₁ClO₂

Purezza: 98+%

Colore e forma: White or cream or pale yellow, Powder

Peso molecolare: 258.70

Ref: 02-A11683

Fmoc-Cl

CAS: 28920-43-6

Reagent for the introduction of the Fmoc-amino-protecting group, which is stable towards acids and catalytic hydrogenation but is readily cleaved under mildly basic non-hydrolytic conditions. The use of this reagent in the protection of hydroxy groups and amino groups in nucleotides has been reported as well. Fmoc-chloride is often used for pre-column derivatization of amines and amino acids in analytical HPLC.

Formula: C₁₅H₁₁ClO₂

Purezza: 98.9%

Colore e forma: Whitish

Peso molecolare: 258.7

Ref: 01-4004776

9H-Fluoren-9-ylmethyl chloroformate

CAS: 28920-43-6

Formula: C₁₅H₁₁ClO₂

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 258.6996

Ref: IN-DA002X2Y

Fmoc chloride

CAS: 28920-43-6

Formula: C₁₅H₁₁ClO₂

Purezza: ≥ 97.0%

Colore e forma: White to off-white or pale yellow-orange crystalline powder

Peso molecolare: 258.70

Ref: 7W-GE3236

(9H-Fluoren-9-yl)methyl chloroformate

CAS: 28920-43-6

(9H-Fluoren-9-yl)methyl chloroformate

Formula: C₁₅H₁₁ClO₂

Purezza: ≥95%

Colore e forma: white to light yellow to orange crystal or chunks or powder

Peso molecolare: 258.69964g/mol

Ref: 54-OR13210

Fmoc-Chloride

CAS: 28920-43-6

Formula: C₁₅H₁₁ClO₂

Purezza: 97.0%

Colore e forma: Solid

Peso molecolare: 258.7

Ref: 10-F022072

(9-Fluorenylmethyl) Chloroformate

CAS: 28920-43-6

Formula: C₁₅H₁₁ClO₂

Peso molecolare: 258.70

Ref: 4Z-C-334007

9-Fluorenylmethyl Chlorocarbonate

CAS: 28920-43-6

Stability Moisture Sensitive
Applications 9-Fluorenylmethyl Chlorocarbonate is an N-Protecting agent for peptides research and was used for the pre-column derivatization of the biogenic amines (BAs) cadaverine (Cad), histamine (Him), octopamine (Ocp), phenylethylamine (Pea), putrescine (Put), spermidine (Spd), spermine (Spm), tyramine (Tym).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rebane, R., et al.: J. Chromatograph. Anal. Technol. Biomed. Life. Sci., 904, 99 (2012); Brueckner, H., et al.: Amino. Acids., 42, 877 (2012);

Formula: C₁₅H₁₁ClO₂

Colore e forma: Light Yellow

Peso molecolare: 258.70

Ref: TR-F472450

Fmoc-Cl

CAS: 28920-43-6

Fmoc-Cl is a fluorescent derivative that can be used as an analytical method for amino acids in human serum. This reagent is synthesized from chloroformate and derivatization of the amino acid with polymyxin B. Fmoc-Cl reacts with amino acids, producing a fluorescent molecule. The reaction solution can be applied to human serum to determine the concentration of various types of amino acids in the sample. The main matrix effect comes from the presence of human serum proteins, which have been shown to interfere with the measurement of some amino acid concentrations. Fmoc-Cl has also been studied as a potential therapeutic agent for autoimmune diseases, such as multiple sclerosis, lupus erythematosus, and rheumatoid arthritis. It has been shown that Fmoc-Cl inhibits complex enzymes and can reduce levels of certain inflammatory markers in animal models.

Formula: C₁₅H₁₁ClO₂

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 258.7 g/mol

Ref: 3D-FF07779

9-Fluorenylmethyl Chloroformate (FMOC Chloride, FMOC-Cl) extrapure, 99%

CAS: 28920-43-6

Formula: C₁₅H₁₁ClO₂

Purezza: min. 99%

Colore e forma: White to off-white, Crystalline powder

Peso molecolare: 258.70

Ref: SR-54083