CAS 29110-48-3

Cloridrato di guanfacina

Descrizione:

Cloridrato di guanfacina è un farmaco utilizzato principalmente per trattare il disturbo da deficit di attenzione e iperattività (ADHD) e l'ipertensione. È un agonista alfa-2 adrenergico, il che significa che agisce stimolando i recettori alfa-2 nel cervello, portando a una diminuzione del flusso simpatico e a una riduzione della pressione sanguigna. La sostanza appare come una polvere cristallina bianca a bianco sporco ed è solubile in acqua, rendendola adatta per somministrazione orale. La sua formula chimica è C9H9ClN2 e ha un peso molecolare di circa 182,63 g/mol. Cloridrato di guanfacina è noto per i suoi effetti sedativi, che possono essere utili nella gestione dei sintomi dell'ADHD promuovendo calma e concentrazione. Il farmaco viene solitamente somministrato in forma di compresse, con il dosaggio regolato in base alla risposta e alla tolleranza del singolo paziente. Gli effetti collaterali comuni possono includere sonnolenza, secchezza delle fauci e affaticamento. Come con qualsiasi farmaco, è essenziale utilizzare Cloridrato di guanfacina sotto la guida di un professionista sanitario per garantire sicurezza ed efficacia.

Formula: C₉H₁₀Cl₃N₃O

InChI: InChI=1/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H

InChI key: InChIKey=DGFYECXYGUIODH-UHFFFAOYSA-N

SMILES: C(C(NC(=N)N)=O)C1=C(Cl)C=CC=C1Cl.Cl

Sinonimi:

• 2,6-Dichlorophenylacetylguanidine hydrochloride
• Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1)
• Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, monohydrochloride
• Bs 100-141
• Estulic
• Guanfacine HCl
• Guanfacine hydrochloride [USAN:JAN]
• Intuniv
• Lon 798
• N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride
• N-(Aminoiminomethyl)-2,6-dichlorophenylacetamide monohydrochloride
• N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride
• N-Amidino-2-(2,6-dichlorophenyl)acetamide monohydrochloride
• Spd 503
• Tenex
• Tenex (pharmaceutical)
• Unii-Pml56A160O
• [(2,6-Dichlorophenyl)acetyl]guanidine monohydrochloride
• n-(aminoiminomethyl)-2,6-dichlorobenzeneacetamidehydrochloride
• [(2,6-DICHLOROPHENYL)ACETYL]GUANIDINE HYDROCHLORIDE
• N (AMINOIMINOMETHYL)-2,6-DICHLOROBENZENEACETAMIDE HYDROCHLORIDE SALT
• Guarfacine
• Guanfascine
• GUANFACINE HYDROCHLORIDE
• GUANFACIN HYDROCHLORIDE
• n-(aminoiminomethyl)-2,6-dichloro-benzeneacetamidmonohydrochloride
• n-amidino-2-(2,6-dichlorophenyl)acetamidehydrochloride
• bs100-141
• lon798

Guanfacine Hydrochloride

CAS: 29110-47-2, 29110-48-3

Formula: C₉H₉Cl₂N₃O·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 282.55

Ref: 3B-G0414

Guanfacine Hydrochloride

CAS: 29110-48-3

Aromatic imines and their derivatives, salts thereof

Formula: C₉H₉Cl₂N₃O·HCI

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 384.92456

Ref: 45-1302101

Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1)

CAS: 29110-48-3

Formula: C₉H₁₀Cl₃N₃O

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 282.5542

Ref: IN-DA002XC9

N-Carbamimidoyl-2-(2,6-Dichlorophenyl)Acetamide Hydrochloride

CAS: 29110-48-3

N-Carbamimidoyl-2-(2,6-Dichlorophenyl)Acetamide Hydrochloride

Purezza: 99%

Peso molecolare: 282.55g/mol

Ref: 54-OR1014312

Guanfacine hydrochloride

CAS: 29110-48-3

Guanfacine hydrochloride

Purezza: ≥98%

Peso molecolare: 282.55g/mol

Ref: 54-BUP13678

Guanfacine HCl

CAS: 29110-48-3

Formula: C₉H₉Cl₂N₃O·HCl

Colore e forma: Off-White Solid

Peso molecolare: 246.09 36.46

Ref: 4Z-G-184

Guanfacine hydrochloride

CAS: 29110-48-3

Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.

Formula: C₉H₁₀Cl₃N₃O

Purezza: 99.89% - 99.91%

Colore e forma: Solid

Peso molecolare: 282.55

Ref: TM-T2150

Guanfacine hydrochloride

CAS: 29110-48-3

Formula: C₉H₉Cl₂N₃O·HCl

Purezza: ≥ 98.0%

Colore e forma: White to almost white crystalline powder

Peso molecolare: 282.55

Ref: 7W-GP1667

Guanfacine Hydrochloride

CAS: 29110-48-3

Formula: C₉H₉Cl₂N₃O·ClH

Colore e forma: Neat

Peso molecolare: 282.55

Ref: TR-G816001

N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride

CAS: 29110-48-3

Formula: C₉H₁₀Cl₃N₃O

Purezza: 99%

Peso molecolare: 282.55

Ref: 10-F234921

Guanfacine HCl

CAS: 29110-48-3

Guanfacine is a centrally acting alpha-2 adrenergic agonist that is used in the treatment of hypertension and attention deficit hyperactivity disorder (ADHD). It is a racemic mixture of two enantiomers, (+) and (-) guanfacine. Guanfacine acts on central alpha-2 receptors to reduce sympathetic outflow from the vasomotor center, which leads to reduced peripheral vascular resistance, decreased blood pressure, and increased heart rate. It also has been shown to increase the release of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits neuronal activity. Guanfacine is metabolized by CYP3A4 and CYP2D6 enzymes with elimination half-life of 10 hours. The drug has minimal drug interactions due to its low protein binding properties. Guanfacine has been found to be safe for use in humans at doses up to 3 mg/kg/day

Formula: C₉H₉Cl₂N₃O·HCl

Purezza: Min. 95%

Peso molecolare: 282.55 g/mol

Ref: 3D-FG33962