CAS 2921-57-5

Succinate di metilprednisolone

Descrizione:

Succinate di metilprednisolone è un corticosteroide sintetico con proprietà anti-infiammatorie e immunosoppressive, comunemente usato nel trattamento di varie condizioni come allergie, disturbi autoimmuni e alcuni tipi di cancro. È un derivato della metilprednisolone, che è una forma modificata dell'ormone steroideo cortisolo. La sostanza è caratterizzata dalla sua capacità di inibire il rilascio di mediatori infiammatori e modulare le risposte immunitarie. Succinate di metilprednisolone è tipicamente somministrato per iniezione ed è noto per il suo rapido inizio d'azione. La sua struttura chimica include un estere succinato, che ne migliora la solubilità e la biodisponibilità. Il composto è generalmente ben tollerato, ma gli effetti collaterali potenziali possono includere un aumento del rischio di infezioni, disturbi gastrointestinali e alterazioni nel metabolismo del glucosio. Come con altri corticosteroidi, l'uso a lungo termine richiede un attento monitoraggio a causa dei possibili effetti avversi su vari sistemi organici. In generale, Succinate di metilprednisolone è un agente terapeutico prezioso nella gestione di condizioni infiammatorie e autoimmuni.

Formula: C₂₆H₃₄O₈

InChI: InChI=1S/C26H34O8/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31)/t14-,16-,17-,19-,23+,24-,25-,26-/m0/s1

InChI key: InChIKey=IMBXEJJVJRTNOW-XYMSELFBSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(COC(CCC(O)=O)=O)=O)O)[H]

Sinonimi:

• (6α,11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
• 11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-(Hydrogen Succinate)
• 4-{[(6Alpha,11Beta)-11,17-Dihydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl]Oxy}-4-Oxobutanoic Acid
• 6-Methylprednisolone hemisuccinate
• 6α-Methylprednisolone 21-succinate
• 6α-Methylprednisolone hemisuccinate
• Methylprednisolone 21-hemisuccinate
• Methylprednisolone succinate
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(H succinate)
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(hydrogen succinate)
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-succinate

Methylprednisolone Hydrogen Succinate

CAS: 2921-57-5

Colore e forma: Neat

Ref: 61-FOR1515.00

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PERFORMANCE TEST CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PERFORMANCE TEST CRS

Colore e forma: Powder

Ref: 41-M1755220

METHYLPREDNISOLONE HYDROGEN SUCCINATE CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE CRS

Formula: C₂₆H₃₄O₈

Colore e forma: Powder

Peso molecolare: 474.5434

Ref: 41-M1755200

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PEAK IDENTIFICATION CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PEAK IDENTIFICATION CRS

Formula: C₂₆H₃₄O₈

Colore e forma: Powder

Peso molecolare: 474.5434

Ref: 41-Y0001759

Methylprednisolone Hemisuccinate

CAS: 2921-57-5

Adrenal cortical hormones and their derivatives nesoi

Formula: C₂₆H₃₄O₈

Colore e forma: White Off-White Powder

Peso molecolare: 474.54

Ref: 45-1437009

Methylprednisolone 21-Hemisuccinate (Methylprednisolone Hydrogen Succinate)

CAS: 2921-57-5

Formula: C₂₆H₃₄O₈

Colore e forma: White To Off-White Solid

Peso molecolare: 474.55

Ref: 4Z-P-11138

Methylprednisolone succinate

CAS: 2921-57-5

Methylprednisolone succinate

Purezza: ≥98%

Peso molecolare: 474.54g/mol

Ref: 54-BUP11730

Methylprednisolone Hydrogen Succinate

Prodotto controllato

CAS: 2921-57-5

Formula: C₂₆H₃₄O₈

Colore e forma: Neat

Peso molecolare: 474.54

Ref: 86-MM1515.00

Methylprednisolone succinate

CAS: 2921-57-5

Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.

Formula: C₂₆H₃₄O₈

Purezza: 98.41% - 99.82%

Colore e forma: White Or Almost-White Solid Powder

Peso molecolare: 474.54

Ref: TM-T22367

Methylprednisolone Succinate RS

CAS: 2921-57-5

Colore e forma: White Solid Crystalline Powder

Ref: 2K-1165000021

Methylprednisolone 21-Hemisuccinate

CAS: 2921-57-5

Formula: C₂₆H₃₄O₈

Peso molecolare: 474.55

Ref: ST-EA-CP-M14014

6a-Methylprednisolone 21-Hemisuccinate

Prodotto controllato

CAS: 2921-57-5

Applications 6α-Methylprednisolone 21-Hemisuccinate is a derivative of methylprednisolone (M325934), a glucocorticoid and a anti-inflammatory drug used to treat central nervous system disorders such as multiple sclerosis. 6α-Methylprednisolone 21-Hemisuccinate was examined for potential therapeutic efficacy in a model of neuroinflammation in rats with acute autoimmune encephalomyelitis.
References Gaillard, P.J., et al.: J. Controlled. Release., 164, 364 (2012);

Formula: C₂₆H₃₄O₈

Colore e forma: White To Off-White

Peso molecolare: 474.54

Ref: TR-M331195

Methylprednisolone hemisuccinate

Prodotto controllato

CAS: 2921-57-5

Meghylprednisolone hemisuccinate is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the group of pharmacological agents. It is used for pain relief in cases of inflammatory bowel disease, and has been shown to be effective against human immunoglobulin A (IgA) nephropathy. Meghylprednisolone hemisuccinate inhibits prostaglandin synthesis by binding to the enzyme cyclooxygenase and blocking the conversion of arachidonic acid to prostaglandins. This drug also blocks the production of leukotrienes, which are mediators of inflammation and tissue injury. Meghylprednisolone hemisuccinate has been shown to be less toxic than methylprednisolone sodium succinate in rats when given at low doses orally, although it has not been studied in humans.

Formula: C₂₆H₃₄O₈

Purezza: Min. 95%

Peso molecolare: 474.54 g/mol

Ref: 3D-FM39645