CAS 2924156-96-5

Tubulin polymerization-IN-68

CAS: 2924156-96-5

Tubulin polymerization-IN-68 (compound 32) serves as a tubulin inhibitor, disrupting cellular microtubule networks by hindering tubulin polymerization. It also upregulates PARP-1 and caspase-3 expression, thereby inducing apoptosis and exhibiting anticancer properties. Notably, Tubulin polymerization-IN-68 effectively suppresses HepG2 cells with an IC50 of 93 nM and markedly reduces the growth of HepG2 xenograft tumors in nude mice through oral administration.

Formula: C₁₆H₁₃N₃O

Colore e forma: Solid

Peso molecolare: 263.29

Ref: TM-T200167