CAS 29428-50-0

Acetato di metile 1,2,3,4-tetraidro-2,4-diosso-1-β-D-ribofuranosil-5-pirimidina

Descrizione:

Acetato di metile 1,2,3,4-tetraidro-2,4-diosso-1-β-D-ribofuranosil-5-pirimidina, con il numero CAS 29428-50-0, è un composto chimico che presenta una struttura complessa caratterizzata da un anello di pirimidina e da un gruppo ribofuranosilico. Questo composto è notevole per la sua potenziale attività biologica, in particolare nel contesto degli analoghi dei nucleosidi, che possono influenzare il metabolismo degli acidi nucleici. La presenza dei gruppi tetraidro e dioxo contribuisce alla sua reattività e stabilità in varie condizioni. Tipicamente, tali composti possono mostrare proprietà come la solubilità in solventi polari e possono partecipare a legami idrogeno grazie alla presenza di gruppi funzionali idrossilici e carbonilici. La funzionalità dell'estere metilico suggerisce che potrebbe subire idrolisi per rilasciare l'acido corrispondente, il che potrebbe ulteriormente influenzare le sue interazioni biologiche. In generale, le caratteristiche strutturali di questo composto lo posizionano come un candidato per la ricerca in chimica medicinale, in particolare nello sviluppo di agenti antivirali o antitumorali.

Formula: C₁₂H₁₆N₂O₈

InChI: InChI=1/C12H16N2O8/c1-21-7(16)2-5-3-14(12(20)13-10(5)19)11-9(18)8(17)6(4-15)22-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,20)/t6-,8-,9-,11-/m1/s1

InChI key: InChIKey=YIZYCHKPHCPKHZ-PNHWDRBUSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(CC(OC)=O)=C2

Sinonimi:

• 5-Carboxymethyluridine methyl ester
• 5-Methoxycarbonyl methyl uridine
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, methyl ester
• Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-5-pyrimidineacetate
• Uridine, 5-(2-Methoxy-2-Oxoethyl)-
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester
• 5-(2-Methoxy-2-oxoethyl)uridine
• Methyl 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate
• 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-beta-D-ribofur anosyl-, methyl ester
• 5-(Methoxycarbonyl) methyluridine (MCM5U
• 5-<(methylcarboxy)methyl>uridine
• 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyrimidineacetic Acid Methyl Ester, 5-(Methoxy carbonyl)-methyluridine, Uridine 5-acetic acid methyl ester
• 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyriMidineacetic Acid Methyl Ester
• 5-(Methoxycarbonyl) methyluridine (MCM5U),Uridine 5-acetic acid methyl ester, RNA mCm5U

5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester

CAS: 29428-50-0

Formula: C₁₂H₁₆N₂O₈

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 316.2640

Ref: IN-DA002YCW

5-(Methoxycarbonyl)methyluridine

CAS: 29428-50-0

5-(Methoxycarbonyl)methyluridine

Purezza: ≥98%

Peso molecolare: 316.26g/mol

Ref: 54-BUP20284

5-(Methoxycarbonyl)methyluridine

CAS: 29428-50-0

5-(Methoxycarbonyl)methyluridine is an important modifying nucleotide in tRNAs, and the lack of the mcm5U modification leads to increased protein aggregation.

Formula: C₁₂H₁₆N₂O₈

Purezza: 99.71%

Colore e forma: Solid

Peso molecolare: 316.26

Ref: TM-TNU0040

5-Methoxycarbonyl Methyl Uridine

Prodotto controllato

CAS: 29428-50-0

Applications 5-Methoxycarbonyl methyl uridine is a nucleoside constituent of yeast transfer RNA. 5-Methoxycarbonyl methyl uridine is also a derivative of 5-carboxymethyluridine, a carboxyl-containing nucleoside that was isolated from transfer RNA of Baker’s Yeast.
References Gray, M. & Lane, B.: Biochemistry, 7, 3441 (1968); Tumaitis, T. & Lane, B.: BBA-Nuc. Acid. Prot. Synth., 224, 391 (1970)

Formula: C₁₂H₁₆N₂O₈

Colore e forma: Neat

Peso molecolare: 316.26

Ref: TR-M261615

5-Methoxycarbonylmethyluridine

CAS: 29428-50-0

5-Methoxycarbonylmethyluridine is a nucleoside that is a precursor in the synthesis of other nucleotides. It has been shown to have potential as a biomarker for various diseases, such as metabolic disorders and hepatic steatosis. 5-Methoxycarbonylmethyluridine also inhibits the activity of methyltransferases, which are enzymes that catalyze the transfer of methyl groups from S-adenosylmethionine to substrates. It is also used as a model system for polymerase chain reaction in cancer research, because it has been shown to inhibit DNA replication by blocking the incorporation of uracil into DNA.
5-Methoxycarbonylmethyluridine has been found at high levels in fetal bovine serum and eukaryotic cells, but not in prokaryotes or cancerous tissues.

Formula: C₁₂H₁₆N₂O₈

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 316.26 g/mol

Ref: 3D-NM45525