CAS 29457-07-6

Ticarcillina disodica

Descrizione:

Ticarcillina disodica è un antibiotico penicillina semisintetico che viene utilizzato principalmente per trattare infezioni causate da batteri Gram-negativi suscettibili. È caratterizzato dalla sua attività ad ampio spettro, in particolare contro Pseudomonas aeruginosa e altre Enterobacteriaceae. Il composto è un sale disodico della ticarcilina, che ne migliora la solubilità in soluzioni acquose, rendendolo adatto per somministrazione endovenosa. La ticarcilina agisce inibendo la sintesi della parete cellulare batterica, portando alla lisi cellulare e alla morte. Viene spesso utilizzata in combinazione con altri antibiotici, come l'acido clavulanico, per superare i meccanismi di resistenza. La sostanza viene tipicamente somministrata in un contesto clinico e la sua farmacocinetica include una rapida distribuzione nei tessuti corporei, con l'escrezione renale come principale via di eliminazione. Gli effetti collaterali comuni possono includere reazioni allergiche, disturbi gastrointestinali e alterazioni nella coagulazione del sangue. Come con tutti gli antibiotici, si raccomanda di effettuare test di suscettibilità appropriati per garantire l'efficacia contro patogeni specifici.

Formula: C₁₅H₁₆N₂O₆S₂·2Na

InChI: InChI=1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/t7-,8-,9+,12-;;/m1../s1

InChI key: InChIKey=IPRJTUDVZGEREZ-QBGWIPKPSA-N

SMILES: N(C([C@H](C(O)=O)C=1C=CSC1)=O)[C@H]2[C@@]3(N([C@@H](C(O)=O)C(C)(C)S3)C2=O)[H].[Na]

Sinonimi:

• 3-Thiophenemalonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-, disodium salt, <span class="text-smallcaps">D</span>-(-)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(carboxy-3-thienylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-[2α,5α,6β(S*)]]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:2), (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-, disodium salt, (2S,5R,6R)-
• 6-<span class="text-smallcaps">D</span>(-)-(α-Carboxy-3-thienylacetamido)penicillanic acid disodium salt
• 6-<span class="text-smallcaps">D</span>-(-)-α-Carboxy-3-thienylmethylacetamido penicillanic acid
• Ab 2288
• Brl 2288
• Disodium ticarcillin
• Monapen
• Ticar
• Ticarcillin Disodium
• Ticarcillin disodium salt
• Ticarcillin sodium
• Ticarcillin sodium salt
• Ticarpen
• disodium (2R,5R,6R)-6-{[carboxylato(thiophen-3-yl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• disodium (2S,5R,6R)-6-{[(2R)-2-carboxylato-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• α-Carboxy-3-thienylmethylpenicillin disodium salt
• 3-Thiophenemalonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-, disodium salt, D-(-)-

Ticarcillin sodium

CAS: 29457-07-6

Ticarcillin sodium

Purezza: ≥95%

Peso molecolare: 430.41g/mol

Ref: 54-BUP16405

Ticarcillin sodium

CAS: 29457-07-6

Ticarcillin sodium: a semisynthetic, broad-spectrum antibiotic effective against various aerobic and anaerobic bacteria.

Formula: C₁₅H₁₆N₂O₆S₂·2Na

Purezza: 99.09%

Colore e forma: Solid

Peso molecolare: 430.41

Ref: TM-T6706

Ticarcillin Disodium Salt (Contain 10% Methanol)

Prodotto controllato

CAS: 29457-07-6

Stability Hygroscopic
Applications The disodium salt of Ticarcillin, a carboxypenicillin belonging to the beta-lactam class of antibiotics. Ticarcillin is an injectable antibiotic used in the treatment of infections caused by gram-negative bacteria, particularly Pseudomonas aeruginosa.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Paisley, J.W. et al.: Antimicrob. Agents Chemother., 14, 224 (1978); Fass, R.J. et al.: Rev. Infect. Dis., 2, 841 (1980); Husson, M.O. et al.: Drugs Exp. Clin. Res., 9, 843 (1983);

Formula: C₁₅H₁₄N₂O₆S₂·2Na

Colore e forma: Neat

Peso molecolare: 428.39

Ref: TR-T437901

Ticarcillin disodium

CAS: 29457-07-6

Ticarcillin is a bactericidal antibiotic that is used to treat many types of infections caused by gram-positive bacteria, such as Streptococcus pneumoniae, Enterococcus faecalis and Enterococcus faecium. Ticarcillin has been shown to be effective against antibiotic-resistant strains of bacteria, including multidrug efflux pumps. This drug also has been shown to inhibit the growth of gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa. Ticarcillin is used in combination with clavulanic acid for the treatment of infections caused by beta-lactamase producing organisms. It is also used in wastewater treatment to inhibit the growth of gram-negative bacteria that are resistant to other antibiotics. Ticarcillin can interfere with other medications by inhibiting their metabolism through cytochrome P450 enzymes or through competition for protein binding sites.

Formula: C₁₅H₁₆N₂Na₂O₆S₂

Purezza: Min. 80.0 Area-%

Colore e forma: White Powder

Peso molecolare: 430.41 g/mol

Ref: 3D-FC75007

Ticarcillin Disodium Salt-13C3 (Contain 10% Methanol)

Prodotto controllato

CAS: 29457-07-6

Formula: C₃C₁₂H₁₄N₂Na₂O₆S₂

Colore e forma: Neat

Peso molecolare: 431.369

Ref: TR-T437902