CAS 2955-27-3

acido ursodesossicolico

Descrizione:

acido ursodesossicolico, noto anche come acido ursodeossicolico (UDCA), è un acido biliare derivato dal metabolismo del colesterolo. È caratterizzato dalle sue proprietà idrofili, che gli consentono di ridurre la solubilità del colesterolo nella bile, contribuendo così a prevenire la formazione di calcoli biliari di colesterolo. La struttura chimica di acido ursodesossicolico presenta un'organizzazione unica di gruppi idrossilici, che contribuisce alla sua capacità di interagire con le membrane cellulari e influenzare vari processi fisiologici. È comunemente utilizzato in contesti clinici per il trattamento di alcune malattie epatiche, come la colangite biliare primaria, ed è noto per i suoi effetti epatoprotettivi. Inoltre, acido ursodesossicolico è stato studiato per i suoi potenziali benefici nel migliorare la sensibilità all'insulina e il suo ruolo nella modulazione del microbiota intestinale. Il suo profilo di sicurezza è generalmente favorevole, rendendolo un agente terapeutico prezioso nella gestione dei disturbi epatici colestatici.

Formula: C₂₄H₄₀O₅

InChI: InChI=1/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19+,20+,22+,23+,24-/m1/s1

InChI key: InChIKey=BHQCQFFYRZLCQQ-UTLSPDKDSA-N

SMILES: O[C@@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]

Sinonimi:

• Cholan-24-oic acid, 3,7,12-trihydroxy-, (3α,5β,7β,12α)-
• (3α,5β,7β,12α)-3,7,12-Trihydroxycholan-24-oic acid
• 5β-Cholan-24-oic acid, 3α,7β,12α-trihydroxy-
• 7-Epicholic acid
• 5β-Cholanic acid, 3α,7β,12α-trihydroxy-
• Ursocholate
• 4-[(5S,7S,8S,10S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid USP/EP/BP
• Chenodeoxycholic Acid Impurity 4
• Ursodeoxycholic Acid EP Impurity D
• Ursodeoxycholic Acid Impurity 4（Ursodeoxycholic Acid EP Impurity D）
• Chenodeoxycholic Acid EP Impurity D
• 4-[(5S,7S,8S,10S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• Ursodeoxycholic Acid EP Impurity D/Ursocholic Acid/(R)-4-((3R,5S,7S,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
• 7β-Hydroxyisocholic Acid
• Ursodiol Impurity D
• Ursocholic Acid (Chenodeoxycholic Acid EP Impurity D, Ursodeoxycholic Acid EP Impurity D)
• Ursocholic acid
• (4R)-4-((3R,5S,7S,8R,9S,10S,12S,13R,14S)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Cholan-24-oic acid, 3,7,12-trihydroxy-, (3α,5β,7β,12α)-

CAS: 2955-27-3

Formula: C₂₄H₄₀O₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 408.5714

Ref: IN-DA002YQ7

Ursocholic Acid (Chenodeoxycholic Acid EP Impurity D, Ursodeoxycholic Acid EP Impurity D)

CAS: 2955-27-3

Formula: C₂₄H₄₀O₅

Colore e forma: White To Off-White Solid

Peso molecolare: 408.58

Ref: 4Z-C-5717

Ursocholic acid

CAS: 2955-27-3

Ursocholic acid

Purezza: ≥95%

Peso molecolare: 408.57g/mol

Ref: 54-BUP08071

Ursocholic acid

CAS: 2955-27-3

Ursocholic acid, a bile acid found predominantly in bile of mammals.

Formula: C₂₄H₄₀O₅

Purezza: 98.89% - 99.62%

Colore e forma: Solid

Peso molecolare: 408.57

Ref: TM-T7331

Chenodeoxycholic Acid EP Impurity D

CAS: 2955-27-3

Formula: C₂₄H₄₀O₅

Peso molecolare: 408.57

Ref: ST-EA-CP-C93004

Ursodeoxycholic Acid EP Impurity D

CAS: 2955-27-3

Formula: C₂₄H₄₀O₅

Peso molecolare: 408.58

Ref: ST-EA-CP-U1004

Ursocholic Acid

Prodotto controllato

CAS: 2955-27-3

Impurity Ursodeoxycholic Acid EP Impurity D
Applications Ursocholic Acid (Ursodeoxycholic Acid EP Impurity D) is an Ursodeoxycholic Acid (U850000) impurity.
References Ward, A., et al.: Drugs, 1984, 27, 95 (1984), Sama, C., et al.: Clin. Drug Invest., 13, 192 (1997), Nobilis, M., et al.: J. Pharm. Biomed. Anal., 24, 937 (2001),

Formula: C₂₄H₄₀O₅

Colore e forma: White To Beige

Peso molecolare: 408.57

Ref: TR-U849900

Ursocholic acid

Prodotto controllato

CAS: 2955-27-3

Ursocholic acid is a bile acid that is used in the treatment of pediatric bowel disease. Ursocholic acid reduces the formation of cholesterol gallstones and its use has been shown to improve the symptoms of congestive heart failure. The mechanism of action for ursocholic acid is not fully understood but it has been shown to increase the amount of serum bile acids and reduce the amount of hydroxyl group in bile acids. Ursocholic acid also increases cell lysis by interacting with hydrophobic regions on the surface of cells. There are high concentrations of ursocholic acid found in human feces, which may be due to its hydrophobic effect. Ursocholic acid also inhibits HIV infection by binding to gp120, preventing gp120 from binding to CD4 receptors on T-cells.

Formula: C₂₄H₄₀O₅

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 408.57 g/mol

Ref: 3D-FU28645