CAS 2956722-48-6

PROTAC FLT-3 degrader 4

CAS: 2956722-48-6

PROTACFLT-3degrader 4 is an orally active CRBN-based FLT3-PROTAC degrader that efficiently induces the degradation of FLT3-ITD via the ubiquitin-proteasome system. It demonstrates high selectivity for FLT3-ITD mutant acute myeloid leukemia (AML) cells. [Blue: CRBN ligand, Black: linker; Pink: FLT3 inhibitor].

Formula: C₃₉H₄₁FN₈O₆

Peso molecolare: 736.79

Ref: TM-T87986