CAS 2962103-54-2

Glycine, N-[[5-[3-(3,5-dichlorophenyl)-5-isoxazolyl]-3-hydroxy-2-pyridinyl]carbonyl]-

Formula: C₁₇H₁₁Cl₂N₃O₅

Sinonimi:

• Glycine, N-[[5-[3-(3,5-dichlorophenyl)-5-isoxazolyl]-3-hydroxy-2-pyridinyl]carbonyl]-

ZG-2305

CAS: 2962103-54-2

ZG-2305 is an effective, selective, and orally active inhibitor of FIH (factor inhibiting hypoxia-inducible factor (FIH)), with Ki values of 79.6 nM for FIH and 2786 nM for PHD2. This compound enhances the expression of the EGLN3 gene, reduces cellular triglyceride levels, and decreases lipid accumulation. ZG-2305 holds potential for research into obesity and fatty liver disease.

Formula: C₁₇H₁₁Cl₂N₃O₅

Colore e forma: Solid

Peso molecolare: 408.19

Ref: TM-T200939