CAS 2978623-09-3

PD-L1/VISTA-IN-1

CAS: 2978623-09-3

PD-L1/VISTA-IN-1 (Compound P17) is an orally active dual inhibitor targeting PD-L1 and VISTA. It effectively hinders the PD-1/PD-L1 interaction (IC50: 0.1492 μM) and the VISTA pathway (KD: 0.2723 μM), leading to the reactivation of T cells. Additionally, PD-L1/VISTA-IN-1 exhibits antitumor activity.

Formula: C₂₂H₂₄N₄O₄

Colore e forma: Solid

Peso molecolare: 408.45

Ref: TM-T205067