CAS 298-93-1

[3-(4,5-Dimetiltiazol-2-il)-2,5-difeniltetrazolio bromuro]

Descrizione:

[3-(4,5-Dimetiltiazol-2-il)-2,5-difeniltetrazolio bromuro], comunemente noto come MTT, è un composto giallo solubile in acqua ampiamente utilizzato nei saggi di viabilità cellulare. La sua struttura chimica presenta un anello di tetrazolio, che è cruciale per la sua funzione come reagente colorimetrico. Una volta ridotto da cellule vitali, l'MTT viene convertito in un prodotto di formazano viola, consentendo la quantificazione dell'attività metabolica cellulare. L'MTT è stabile in condizioni normali, ma deve essere conservato in un luogo fresco e buio per prevenire la degradazione. È solubile in soluzioni acquose a pH fisiologico, rendendolo adatto per applicazioni biologiche. Il composto è non tossico per le cellule a basse concentrazioni, il che è essenziale per valutazioni di viabilità accurate. I saggi di MTT sono comunemente impiegati in farmacologia e tossicologia per valutare gli effetti di farmaci e altre sostanze sulla salute cellulare. Tuttavia, è necessario prestare attenzione nell'interpretare i risultati, poiché fattori come il tipo di cellula e le condizioni del saggio possono influenzare i risultati. In generale, l'MTT è uno strumento prezioso nella ricerca per valutare la salute e la proliferazione cellulare.

Formula: C₁₈H₁₆N₅S·Br

InChI: InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1

InChI key: InChIKey=AZKSAVLVSZKNRD-UHFFFAOYSA-M

SMILES: CC=1N=C(N2[N+](=NC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)SC1C.[Br-]

Sinonimi:

• 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
• Thiazolyl Blue
• 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide
• Thiazolyl Blue tetrazolium bromide
• Mtt (1.11714)
• 3-(4,5-dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-1-ium bromide
• 3-(4,5-Dimethyl-2-thizolyl)-2,5-diphenyltertazolium bromide
• 3-(4,5-Dimethyl-2-THIAZOL-2-YL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE
• 3-(4,5-Dimethyl-2-THIAZOLYL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE
• 3-(4,5-Dimethylithiazolyl-2)-2,5-Diphenyl Monotetrazolium Bromide
• 3,[4,5-Dimethylthiazol-2-YL]-2,5-DIPHENYLTETRAZOLIUM BROMIDE
• 3-(4,5-Dimethylthiazol-2-YL)-2,5-DIPHYL-2 H-TETRAZOLIUM BROMIDE
• 3-(4,5-Dimethylthiazolyl-2)-2,5-DIPHENYL TETRAZOLIUM BROMIDE
• Methylthiazoletetrazolium
• 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyl-2H-Tetrazoliumbromide
• 3-(4,5-dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2H-tetrazol-3-ium bromide
• 4,5-Dimethythiazoyl-Zyl2,5-Diphenylterrajolium Bromiole
• 2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazolium bromide
• 2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)-2H-tetrazolium bromide
• 2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)tetrazolium bromide
• 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide
• 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (1:1)
• 3-(4',5'-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide
• 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromid
• 3-(4,5-Dimethylthiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
• 3-(4,5-Dimethylthiazolyl)-2,5-diphenyltetrazolium bromide
• Bromure de 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
• Bromure De 3-(4,5-Dimethylthiazole-2-Yl)-2,5-Diphenyltetrazolium
• Bromuro De 3-(4,5-Dimetiltiazol-2-Il)-2,5-Difeniltetrazolio
• MMT Tetrazolium
• MTT tetrazolium
• Nsc 60102
• Thiazolyl blue (Sigma)
• Thiazolyl Blue Monotetrazolium

MTT [for Biochemical Research]

CAS: 298-93-1

Formula: C₁₈H₁₆BrN₅S

Purezza: >97.0%(HPLC)

Colore e forma: Light yellow to Brown powder to crystal

Peso molecolare: 414.33

Ref: 3B-M3297

3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide

CAS: 2348-71-2, 298-93-1

Formula: C₁₈H₁₆BrN₅S

Purezza: >98.0%(T)

Colore e forma: Light yellow to Brown powder to crystal

Peso molecolare: 414.33

Ref: 3B-D0801

Thiazolyl Blue tetrazolium bromide, 98%

CAS: 298-93-1

Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicato

Formula: C₁₈H₁₆BrN₅S

Purezza: 98%

Colore e forma: Crystals or powder or crystalline powder, White to yellow

Peso molecolare: 414.33

Ref: 02-L11939

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide

CAS: 298-93-1

Formula: C₁₈H₁₆BrN₅S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 414.3221

Ref: IN-DA003URZ

Thiazolyl Blue, 10mM (in DMSO)

CAS: 298-93-1

Thiazolyl Blue, 10mM (in DMSO)

Purezza: ≥98%

Peso molecolare: 414.32g/mol

Ref: 54-BUP19260

Thiazolyl blue tetrazolium bromide

CAS: 298-93-1

Formula: C₁₈H₁₆BrN₅S

Purezza: ≥ 98.0%

Colore e forma: Pale yellow to yellow crystalline powder

Peso molecolare: 414.33

Ref: 7W-GC4568

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide

CAS: 298-93-1

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide

Formula: C₁₈H₁₆N₅S·Br

Purezza: 95%

Colore e forma: yellow solid

Peso molecolare: 414.32214g/mol

Ref: 54-BID2165

Thiazolyl Blue

CAS: 298-93-1

Thiazolyl Blue (MTT) is a colorimetric compound widely used in measuring cell proliferation. It is reduced from yellow color to purple formazan in living cells.

Formula: C₁₈H₁₆BrN₅S

Purezza: 98.73% - 99.65%

Colore e forma: Yellow Powder Yellowish Orange Crystalline Powder

Peso molecolare: 414.32

Ref: TM-T19029

2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromide

CAS: 298-93-1

Purezza: 95%

Peso molecolare: 414.3299865722656

Ref: 10-F868291

MTT

CAS: 298-93-1

Applications MTT (cas# 298-93-1) is a useful research chemical. Dyes and metabolites.

Formula: C₁₈H₁₆N₅SBr

Colore e forma: Neat

Peso molecolare: 414.32

Ref: TR-M760505

Methylthiazolyldiphenyl-tetrazolium bromide

CAS: 298-93-1

Purezza: 98.0%

Colore e forma: Solid

Peso molecolare: 414.3299865722656

Ref: 10-F047891

Thiazolyl blue tetrazolium bromide

CAS: 298-93-1

Thiazolyl blue tetrazolium bromide, also called 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide and methylthiazolyldiphenyl-tetrazolium bromide, and mainly known as MTT, is employed in the so-called MTT reduction or colorimetric assay. The MTT assay is used to determine the metabolic activity of living cells and the viable cell number in proliferation and cytotoxicity studies. The assay is based on the enzymatic reduction of the yellow MTT to the purple-blue water-insoluble formazan catalysed by mitochondrial dehydrogenases of living cells. The amount of formazan produced is directly proportional to the number of viable cells and can be quantified by measuring absorbance at 570nm. The MTT assay is broadly employed in cell biology because it is rapid and economical. MTT is also used as enzyme substrates in studies of nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Formula: C₁₈H₁₆BrN₅S

Purezza: Min. 97 Area-%

Colore e forma: Yellow Powder

Peso molecolare: 414.32 g/mol

Ref: 3D-ET15853

Thiazolyl Blue Tetrazolium Bromide (MTT) for tissue culture, 98%

CAS: 298-93-1

Formula: C₁₈H₁₆N₅SBr

Purezza: min. 98%

Colore e forma: Yellow, Crystalline powder, Clear, Yellow

Peso molecolare: 414.32

Ref: SR-58945

Thiazolyl Blue Tetrazolium Bromide (MTT) extrapure AR, 98%

CAS: 298-93-1

Formula: C₁₈H₁₆N₅SBr

Purezza: min. 98%

Colore e forma: Yellow, Crystalline powder, Clear, Yellow

Peso molecolare: 414.32

Ref: SR-33611

Thiazolyl Blue Tetrazolium Bromide

CAS: 298-93-1

Thiazolyl blue tetrazolium bromide, also called 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide and methylthiazolyldiphenyl-tetrazolium bromide, and mainly known as MTT, is employed in the so-called MTT reduction or colorimetric assay. The MTT assay is used to determine the metabolic activity of living cells and the viable cell number in proliferation and cytotoxicity studies. The assay is based on the enzymatic reduction of the yellow MTT to the purple-blue water-insoluble formazan catalysed by mitochondrial dehydrogenases of living cells. The amount of formazan produced is directly proportional to the number of viable cells and can be quantified by measuring absorbance at 570nm. The MTT assay is broadly employed in cell biology because it is rapid and economical. MTT is also used as enzyme substrates in studies of nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Formula: C₁₈H₁₆BrN₅S

Purezza: Min. 95.0 Area-%

Peso molecolare: 414.32 g/mol

Ref: 3D-T-3450