CAS 302-79-4

Acido retinoico

Descrizione:

Acido retinoico, con il numero CAS 302-79-4, è un metabolita della vitamina A (retinolo) e gioca un ruolo cruciale in vari processi biologici, inclusi la crescita cellulare, la differenziazione e lo sviluppo embrionale. Esiste in due forme principali: tutto-trans-Acido retinoico e 13-cis-Acido retinoico, ognuna delle quali presenta attività biologiche distinte. Acido retinoico è un composto lipofilo, il che significa che è solubile in solventi organici ma ha una solubilità limitata in acqua. Agisce principalmente attraverso recettori nucleari, influenzando l'espressione genica e le funzioni cellulari. Questo composto è essenziale in dermatologia, in particolare nel trattamento dell'acne e dell'invecchiamento della pelle, poiché promuove il ricambio cellulare e riduce l'ipercheratinizzazione. Inoltre, Acido retinoico è coinvolto nella regolazione delle risposte immunitarie e ha potenziali applicazioni terapeutiche nel trattamento del cancro, in particolare nella leucemia promielocitica acuta. Tuttavia, il suo utilizzo deve essere attentamente monitorato a causa dei potenziali effetti collaterali, inclusi la teratogenicità e l'irritazione della pelle. In generale, Acido retinoico è un composto vitale sia nei processi fisiologici che nelle applicazioni terapeutiche.

Formula: C₂₀H₂₈O₂

InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+

InChI key: InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N

SMILES: C(=C/C(=C/C=C/C(=C/C(O)=O)/C)/C)\C=1C(C)(C)CCCC1C

Sinonimi:

• (11Cis,13Cis)-7,8-Dihydroretinoic Acid
• (9Cis)-Retinoic Acid
• (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
• (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid
• 15-Oxidoretinal
• 2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
• 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
• Aberel
• Acide retinoique
• Agn 100335
• Airol
• Aknoten
• Atra
• Atragen
• Cordes Vas
• Dermairol
• Epi-Aberel
• Eudyna
• N,N'-hexane-1,6-diyldiacetamide
• Nsc 122578
• Nsc 122758
• Renova
• Retacnyl
• Retin A
• Retinoic Acid
• Retinoic acid, all-trans-
• Retionoic Acid
• Ro 1-5488
• Tretin M
• Tretin M, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
• Tretinion
• Tretinoin (Retionoic Acid)
• Tretinoine
• Tretinoino
• Vesanoid
• Vesnaroid
• Vitamin A acid
• Vitamin A acid, all-trans-
• Vitamin A1 acid, all-trans-
• Vitamin A₁ acid, all-trans-
• all-(E)-Retinoic acid
• all-trans-Retinoic acid
• all-trans-Tretinoin
• all-trans-Vitamin A acid
• all-trans-β-Retinoic acid
• trans-Retinoic acid
• β-Retinoic acid
• Tretinoein
• Tretinoin
• AKOS 92103
• 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2Z,4E,6E,8E-NONATETRANENOIC ACID
• ALL-TRANS-RETINOIE ACID
• ISOTRETINOIN
• 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2E,4E,6E,8E-NONATETRAENOIC ACID
• RETINOIC ACID ALL TRANS ISOMER
• 13-CIS-RETINOIC ACID
• 9-TRANS-TRETINOIN
• (L)-ISOTRETINOIN
• TRANS VITAMIN A ACID
• RETINOIC ACID, 13-CIS-

Retinoic Acid

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Purezza: >93.0%(HPLC)

Colore e forma: Light yellow to Amber to Dark green powder to crystal

Peso molecolare: 300.44

Ref: 3B-R0064

Retinoic acid, 97%

CAS: 302-79-4

Retinoic acid (tretinoin or all-trans-retinoic acid (ATRA)), 302-79-4, is a naturally occuring derivative of retinol which is implicated in cell differentiation. Learn more.

Formula: C₂₀H₂₈O₂

Purezza: 97%

Colore e forma: Pale yellow to yellow, Powder or crystalline powder

Peso molecolare: 300.44

Ref: 02-044540

TRETINOIN CRS

CAS: 302-79-4

TRETINOIN CRS

Formula: C₂₀H₂₈O₂

Colore e forma: Added Modified

Peso molecolare: 300.4351

Ref: 41-T1850000

Tretinoin

CAS: 302-79-4

Tretinoin

Formula: C₂₀H₂₈O₂

Purezza: 99.5%

Colore e forma: Yellow

Peso molecolare: 300.20893

Ref: 47-1205

Retinoic acid

CAS: 302-79-4

Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.

Formula: C₂₀H₂₈O₂

Purezza: 97.21% - 99.6%

Colore e forma: Yellow-Orange Powder

Peso molecolare: 300.44

Ref: TM-T1051

Retinoic acid

CAS: 302-79-4

Retinoic acid

Purezza: ≥95%

Peso molecolare: 300.44g/mol

Ref: 54-BUP14667

Retinoic Acid

CAS: 302-79-4

Retinoic Acid

Formula: C₂₀H₂₈O₂

Purezza: 99%

Colore e forma: yellow to amber to dark green crystal or powder

Peso molecolare: 300.44g/mol

Ref: 54-OR1014889

Retinoic acid

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Purezza: 98.0 - 102.0 % (dried basis)

Colore e forma: Yellow powder

Peso molecolare: 300.44

Ref: 7W-GP4026

Tretinoin (Retinoic Acid, Isotretinoin EP Impurity A)

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Peso molecolare: 300.44

Ref: 4Z-T-114001

Retinoic acid, USP grade

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Purezza: (Titration) 97.0 - 103.0 % (dried basis)

Colore e forma: Yellow to light-orange crystalline powder

Peso molecolare: 300.44

Ref: 7W-GP2891

Tretinoin-d5 (Retinoic Acid-d5, Isotretinoin EP Impurity A-d5)

CAS: 302-79-4, 78996-15-3

Formula: C₂₀H₂₃D₅O₂

Colore e forma: Pale Yellow Solid

Peso molecolare: 305.47

Ref: 4Z-T-114002

Tretinoin

Prodotto controllato

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Colore e forma: Neat

Peso molecolare: 300.44

Ref: 04-C17608000

Tretinoin

Prodotto controllato

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Colore e forma: Yellow

Peso molecolare: 300.44

Ref: 86-MM1110.00

all-trans-Retinoic Acid

CAS: 302-79-4

Stability Light Sensitive
Applications Physiological metabolite of vitamin A. Effects gene expression via nuclear retinoic acid receptors (RAR); mediates cellular growth and differentiation.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kamm, J.J., et al.: J. Am. Acad. Dermatol., 6, 652 (1982), Warrel, R.P., et al.: Leukemia, 8, 929 (1994), Sasai, Y., et al.: J. Neurol., 249, 41 (2002),

Formula: C₂₀H₂₈O₂

Colore e forma: Yellow

Peso molecolare: 300.44

Ref: TR-R250200

all-trans-Retinoic acid

Prodotto controllato

CAS: 302-79-4

Retinoic acid receptor (RAR) agonist; inhibits melanocyte activity

Formula: C₂₀H₂₈O₂

Purezza: Min. 95%

Colore e forma: Yellow Powder

Peso molecolare: 300.44 g/mol

Ref: 3D-FR17921

Tretinoin - Bio-X ™

Prodotto controllato

CAS: 302-79-4

Tretinoin is a type of retinoic acid that can be used for the treatment of acne. It is a chemical inhibitor that binds to nuclear receptors and leads to an increase in apoptosis. This type of retinoic acid helps with cell detachment and increases shedding thus increasing cell turnover. Tretinoin has been shown to have antibacterial efficacy against Staphylococcus aureus, as well as synergistic effects when combined with other agents, such as cyclic lipopeptide antibiotics and quinolones. Additionally, Tretinoin is used in the research and treatment for promyelocytic leukaemia.

Formula: C₂₀H₂₈O₂

Purezza: Min. 95%

Colore e forma: Yellow Powder

Peso molecolare: 300.44 g/mol

Ref: 3D-BR164493

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Purezza: 98%

Colore e forma: Solid, Yellow powder

Peso molecolare: 300.442

Ref: 10-F317904

all-trans-Retinoic Acid (10,11,14,15-13C4)

Prodotto controllato

CAS: 302-79-4

Formula: C₄C₁₆H₂₈O₂

Colore e forma: Neat

Peso molecolare: 304.406

Ref: TR-R250203

Isotretinoin EP Impurity A

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Peso molecolare: 300.44

Ref: ST-EA-CP-I25001

Tretinoin

CAS: 302-79-4

Vitamins a and their derivatives unmixed

Formula: C₂₀H₂₈O₂

Colore e forma: Yellow Powder

Peso molecolare: 300.44

Ref: 45-1674004