CAS 30246-33-4

acido (6R-trans)-7-amino-3-[[(5-metil-1,3,4-tiadiazol-2-il)tio]metil]-8-osso-5-tia-1-azabiciclo[4.2.0]ott-2-ene-2-carbossilico

Descrizione:

La sostanza chimica nota come acido (6R-trans)-7-amino-3-[[(5-metil-1,3,4-tiadiazol-2-il)tio]metil]-8-osso-5-tia-1-azabiciclo[4.2.0]ott-2-ene-2-carbossilico, con il numero CAS 30246-33-4, è un composto sintetico che appartiene alla classe degli antibiotici. Presenta una struttura biciclica, caratteristica di alcuni antibiotici beta-lattamici, e contiene un gruppo tiadiazolico che contribuisce alla sua attività biologica. La presenza di un gruppo amminico e di un gruppo funzionale acido carbossilico suggerisce potenziali interazioni con bersagli biologici, migliorando le sue proprietà farmacologiche. Questo composto è noto per la sua attività antibatterica, in particolare contro una gamma di batteri Gram-positivi e Gram-negativi. Le sue caratteristiche strutturali uniche possono anche influenzare la sua solubilità, stabilità e meccanismo d'azione. Come per molti antibiotici, comprendere le sue caratteristiche è fondamentale per valutare il suo potenziale terapeutico e il profilo di sicurezza nelle applicazioni cliniche.

Formula: C₁₁H₁₂N₄O₃S₃

InChI: InChI=1/C11H12N4O3S3/c1-4-13-14-11(21-4)20-3-5-2-19-9-6(12)8(16)15(9)7(5)10(17)18/h6,9H,2-3,12H2,1H3,(H,17,18)/t6-,9-/m0/s1

InChI key: InChIKey=HJSGHKMSDOLGJJ-HZGVNTEJSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CSC=3SC(C)=NN3)[H]

Sinonimi:

• (6R,7R)-7-Amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6S,7S)-7-ammonio-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (7R)-7-amino-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R-trans)-
• 7-Amino-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-δ-3-cephem-4-carboxylic acid
• 7-Amino-3-[(2-methyl-1,3,4-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid
• 7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Thiomethyl]Cephalosphoranic Acid
• 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic acid
• 7-Tda
• 7-Zaca
• Parent nucleus of cefazedone
• (6R-trans)-7-Amino-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
• Cefazolin EP Impurity A
• Cefuroxime nucleus (7-TDA)
• (7r)-7-amino-3-[(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl]-3-cephem-4-carboxylicacid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R,7R)-
• Parent nucleus of cefazedone (7-TDA)
• Cefazolin Impurity 7(Cefazolin EP Impurity A)
• Cefazolin USP Impurity K
• TDA
• 3,5-Dichloro-4-hydroxypyridine，7-Amino-3-[(5-methyl-1,3,4-thiadiazol- 2-ylthio)methyl]-3-cephem-4- carboxylic Acid
• Cefazolin Impurity EP-A
• 7-Amino-3-[[(5-methyl-1,3,4-thiadiazol-2yl)thiomethyl]-3-cephalosporanicacid
• 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-yl)-thiomethyl]-cephalosporanic aci
• 7-ammonio-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Cefazolin IMpurity A
• (6R)-7α-Amino-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Cefazolin Sodium Impurity A
• (6R,7R)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7-Amino-3-([5-methyl-1,3,4-thiadiazol-2-yl] thiomethyl)-3-cephem-4-carboxylic acid

7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Thiomethyl]Cephalosphoranic Acid

CAS: 30246-33-4

Formula: C₁₁H₁₂N₄O₃S₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 344.4330

Ref: IN-DA00BDYC

Cefazolin EP Impurity A

CAS: 30246-33-4

Formula: C₁₁H₁₂N₄O₃S₃

Colore e forma: White To Off-White Solid

Peso molecolare: 344.44

Ref: 4Z-C-9611

7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-yl)Thiomethyl]Cephalosphoranic Acid

CAS: 30246-33-4

7-Amino-3-[(5-Methyl-1,3,4-Thiadiazol-2-yl)Thiomethyl]Cephalosphoranic Acid

Purezza: 99%

Peso molecolare: 344.44g/mol

Ref: 54-OR1012052

7-ZACA

CAS: 30246-33-4

7-ZACA (cefazolin decarboxylated) is a decarboxylated derivative of cefazolin.

Formula: C₁₁H₁₂N₄O₃S₃

Purezza: 99.73%

Colore e forma: Solid

Peso molecolare: 344.42

Ref: TM-T66940

7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid

Prodotto controllato

CAS: 30246-33-4

Impurity Cefazolin EP Impurity A
Applications 7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid (Cefazolin EP Impurity A) is a substrate used in the assessment of immobilized PGA orientation and in the synthesis of beta lactam antibiotics.
References Serra, I. et al.: Anal. Bioanal. Chem., 405, 745 (2013); Terreni, M. et al.: App. Microbiol. Biotech., 77, 579 (2007); Kurochkina, V. et al.: Biocat. Biotransform., 20, 35 (2002)

Formula: C₁₁H₁₂N₄O₃S₃

Colore e forma: Neat

Peso molecolare: 344.43

Ref: TR-A618190

(6R,7R)-7-Amino-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 30246-33-4

Purezza: 97.0%

Peso molecolare: 344.4200134277344

Ref: 10-F546079

Cefazolin impurity A

CAS: 30246-33-4

Cefazolin impurity A is a by-product in the synthesis of Cefazolin, which is a drug product. It has CAS No. 30246-33-4 and is used as an impurity standard for analytical purposes. The Impurity Standard is also known as Metabolite A. Research and Development (R&D) studies are needed to identify the appropriate analytical impurities for this API, which will be reported on Pharmacopoeia's List of Impurities for reference. The high purity and custom synthesis of this API makes it ideal for use in R&D studies, HPLC standards, or niche markets.
CAS No.: 30246-33-4
Synonyms: Metabolite A
Formula: C11H14N2O5S
Molecular weight: 289.24 g/mol
Appearance: white solid powder

Formula: C₁₁H₁₂N₄O₃S₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 344.44 g/mol

Ref: 3D-IC63651

Cefazolin EP Impurity A

CAS: 30246-33-4

Formula: C₁₁H₁₂N₄O₃S₃

Peso molecolare: 344.42

Ref: ST-EA-CP-C149001