CAS 303-47-9

Ocratossina A

Descrizione:

Ocratossina A è una micotossina prodotta da alcune specie di funghi, in particolare Aspergillus e Penicillium. È un metabolita secondario che si trova comunemente in vari prodotti agricoli, tra cui cereali, caffè e frutta secca. Chimicamente, è classificato come un composto fenolico ed è caratterizzato dalla sua struttura, che include un gruppo di fenilalanina legato a un'unità di 3-carbossy-4-idrossi-2-piridone. Ocratossina A è noto per i suoi potenziali effetti nefrotossici, immunotossici e cancerogeni negli esseri umani e negli animali, rendendolo una preoccupazione significativa per la sicurezza alimentare e la salute pubblica. È stabile in varie condizioni ambientali, il che contribuisce alla sua persistenza nei prodotti alimentari contaminati. Le agenzie di regolamentazione hanno stabilito limiti per Ocratossina A negli alimenti e nei mangimi per mitigare i rischi per la salute. I metodi di rilevamento coinvolgono tipicamente tecniche avanzate come la cromatografia liquida ad alte prestazioni (HPLC) accoppiata alla rilevazione per fluorescenza, garantendo un monitoraggio accurato di questo contaminante nocivo nelle forniture alimentari.

Formula: C₂₀H₁₈ClNO₆

InChI: InChI=1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1

InChI key: InChIKey=RWQKHEORZBHNRI-BMIGLBTASA-N

SMILES: ClC1=C2C(=C(O)C(C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)=C1)C(=O)O[C@H](C)C2

Sinonimi:

• (R)-N-((5-Chlor-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-benzo[c]pyran-7-yl)carbonyl)-3-phenylalanin
• (R)-N-((5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-benzo[c]pyran-7-yl)carbonyl)-3-phenylalanine
• (R)-N-((5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-benzo[c]pyranne-7-yl)carbonyl)-3-phenylalanine
• (R)-N-((5-cloro-3,4-dihidro-8-hidroxi-3-metil-1-oxo-1H-benzo[c]pirano-7-il)carbonil)-3-fenilalanina
• 3R,14S-Ochratoxin A
• <span class="text-smallcaps">L</span>-Phenylalanine, N-[(5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl]-, (R)-
• <span class="text-smallcaps">L</span>-Phenylalanine, N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-
• Alanine, N-[(5-chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl]-3-phenyl-, (-)-
• L-Phenylalanine, N-[(5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl]-, (R)-
• N-[[(3R)-5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-<span class="text-smallcaps">L</span>-phenylalanine
• Nsc 201422
• Nsc 221991
• Ochratoxin A
• Phe-OTA
• Phenylalanine-ochratoxin A
• 5-18-09-00056 (Beilstein Handbook Reference)
• N-[(5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl)carbonyl]phenylalanine
• CCRIS 2382
• N-(((3R)-5-Chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenyl-L-alanine
• N-{[(3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl]carbonyl}phenylalanine
• (-)-N-((5-Chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenylalanine
• N-[[(3R)-5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine
• (R)-N-((5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1 H-2-benzopyran-7-yl)carbonyl)phenylalanine
• NCI-C56586
• (2S)-2-({[(3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl]carbonyl}amino)-3-phenylpropanoate
• L-Phenylalanine, N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-
• L-Phenylalanine, N-(((3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl)-
• HSDB 4305
• N-{[(3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromen-7-yl]carbonyl}-L-phenylalanine
• BRN 1301486

Ochratoxin A in Methanol

CAS: 303-47-9

Methanol

Formula: C₂₀H₁₈ClNO₆

Colore e forma: Solid

Peso molecolare: 403.8

Ref: BE-BePure-24504LM-10

Ochratoxin A in Acetonitrile

CAS: 303-47-9

Acetonitrile

Formula: C₂₀H₁₈ClNO₆

Colore e forma: Solid

Peso molecolare: 403.8

Ref: BE-BePure-24504A5A-5

Ochratoxin A in Acetonitrile

CAS: 303-47-9

Acetonitrile

Formula: C₂₀H₁₈ClNO₆

Colore e forma: Solid

Peso molecolare: 403.8

Ref: BE-BePure-24504LA-10

Ochratoxin A in Acetonitrile

CAS: 303-47-9

Acetonitrile

Formula: C₂₀H₁₈ClNO₆

Colore e forma: Solid

Peso molecolare: 403.8

Ref: BE-BePure-24504XA-100

Ochratoxin A

CAS: 303-47-9

Formula: C₂₀H₁₈ClNO₆

Colore e forma: Solid

Peso molecolare: 403.8

Ref: BE-BePure-24504

Ochratoxin A (10 μg/mL in Acetonitrile)

CAS: 303-47-9

Formula: C₂₀H₁₈ClNO₆

Colore e forma: Single Solution

Peso molecolare: 403.81

Ref: TR-KIT9050

Ochratoxin A

Prodotto controllato

CAS: 303-47-9

Ochratoxin A is a mycotoxin that is found in cereals and cereal products. It can be detected by an analytical method that utilizes high performance liquid chromatography with fluorescence detection. Ochratoxin A has been implicated in the development of bowel diseases and has also been shown to inhibit catalase, peroxidase, and glucose-6-phosphate dehydrogenase activities. It also inhibits DNA polymerase, RNA polymerase, and mitochondrial enzymes involved in energy production. There is evidence that ochratoxin A may be genotoxic by inhibiting the repair of DNA damage caused by reactive oxygen species. The optimum concentration for ochratoxin A is between 0.1 and 1 micrograms per liter.br>
Ochratoxin A is metabolized in plants via the phenylalanine pathway. This leads to increased levels of phenylalanine and p-hydroxybenzoic acid in the plant's tissues.br>

Formula: C₂₀H₁₈ClNO₆

Purezza: (%) Min. 95%

Colore e forma: White Powder

Peso molecolare: 403.81 g/mol

Ref: 3D-FO26489

Ochratoxin A

CAS: 303-47-9

Formula: C₂₀H₁₈ClNO₆

Peso molecolare: 403.81

Ref: ST-EA-CP-O131000