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CAS 3037315-44-6

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  • KNa1.1-IN-2
    Targetmol
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    KNa1.1-IN-2

    CAS:
    <p>KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.</p>
    Formula:C24H27NO
    Colore e forma:Solid
    Peso molecolare:345.48

    Ref: TM-T203619