CAS 304-20-1

Cloridrato di idralazina

Descrizione:

Cloridrato di idralazina è un composto farmaceutico utilizzato principalmente come agente antihipertensivo per gestire l'ipertensione. È classificato come un vasodilatatore, il che significa che agisce rilassando i vasi sanguigni, riducendo così il carico di lavoro del cuore. La formula chimica di Cloridrato di idralazina è C8H8N4·HCl, il che indica che contiene un gruppo idrazina, essenziale per la sua attività biologica. Questo composto viene tipicamente somministrato per via orale o endovenosa ed è noto per il suo rapido inizio d'azione. Cloridrato di idralazina è caratterizzato dalla sua apparenza cristallina bianca a bianco sporco ed è solubile in acqua, rendendolo adatto per varie formulazioni. Gli effetti collaterali comuni possono includere mal di testa, palpitazioni e disturbi gastrointestinali. È importante monitorare i pazienti per possibili reazioni avverse, come la sindrome simile al lupus, specialmente con l'uso a lungo termine. In generale, Cloridrato di idralazina gioca un ruolo significativo nella gestione dell'ipertensione, in particolare nei casi in cui altri trattamenti potrebbero non essere efficaci.

Formula: C₈H₈N₄·ClH

InChI: InChI=1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5H,9H2,(H,11,12);1H

InChI key: InChIKey=ZUXNZUWOTSUBMN-UHFFFAOYSA-N

SMILES: N(N)=C1C=2C(C=NN1)=CC=CC2.Cl

Sinonimi:

• (Phthalazin-1-yl)hydrazine hydrochloride
• 1(2H)-Phthalazinone hydrazone
• 1(2H)-Phthalazinone, hydrazone, monohydrochloride
• 1-Hydrazinophthalazine hydrochloride
• 1-Hydrazinophthalazine monohydrochloride
• 1-Hydrazinylphthalazine
• 1-Hydrazinylphthalazine Hydrochloride (1:1)
• 1-Hydrazinylphthalazine hydrochloride
• Apresoline hydrochloride
• Apulon
• Hydralazine chloride
• Hydralazine hcl
• Hydralazine monohydrochloride
• Lopres
• Phthalazine, 1-hydrazino-, monohydrochloride
• Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)

1-Hydrazinophthalazine Hydrochloride

CAS: 304-20-1, 86-54-4

Formula: C₈H₈N₄·HCl

Purezza: >99.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 196.64

Ref: 3B-H0409

1-Hydrazinophthalazine hydrochloride, 98%

CAS: 304-20-1

A monoamine oxidase inhibitor1-Hydrazinophthalazine hydrochloride is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes. It acts as a non-selective MAO-A/B inhibitor and semicarbazide sensitive amine oxidase inhibitor. Further, it serves as

Formula: C₈H₈N₄•HCl

Purezza: 98%

Colore e forma: White to pale cream, Powder or crystals or crystalline powder

Peso molecolare: 196.64

Ref: 02-B22995

HYDRALAZINE HYDROCHLORIDE CRS

CAS: 304-20-1

HYDRALAZINE HYDROCHLORIDE CRS

Formula: C₈H₉ClN₄

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 196.6369

Ref: 41-H1120000

Hydralazine Hydrochloride

CAS: 304-20-1

Hydralazine hydrochloride

Formula: C₈H₈N₄·HCl

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 160.0749

Ref: 45-1313006

Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)

CAS: 304-20-1

Formula: C₈H₉ClN₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 196.6369

Ref: IN-DA003006

Hydralazine hydrochloride

CAS: 304-20-1

Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.

Formula: C₈H₉ClN₄

Purezza: 99.85% - 99.86%

Colore e forma: Yellow Crystals White Crystalline Solid

Peso molecolare: 196.64

Ref: TM-T1613

Hydralazine hydrochloride

CAS: 304-20-1

Hydralazine hydrochloride

Purezza: ≥98%

Peso molecolare: 196.64g/mol

Ref: 54-BUP17906

Hydralazine hydrochloride

CAS: 304-20-1

Formula: C₈H₈N₄HCl

Peso molecolare: 196.64

Ref: 7W-GL6824

Hydralazine HCl (Dihydralazine EP Impurity C HCl)

CAS: 304-20-1

Formula: C₈H₈N₄·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 160.18 36.46

Ref: 4Z-H-135

1-hydrazinyl-Phthalazine hydrochloride

CAS: 304-20-1

1-hydrazinyl-Phthalazine hydrochloride

Purezza: 98%

Peso molecolare: 196.64g/mol

Ref: 54-OR1009501

Hydralazine hydrochloride

CAS: 304-20-1

Formula: C₈H₈N₄·ClH

Colore e forma: Neat

Peso molecolare: 196.64

Ref: 04-C14219100

Hydralazine Hydrochloride

Prodotto controllato

CAS: 304-20-1

Applications Hydralazine is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumour suppressor genes (1,2,3). It is also a non-selective MAO-A/B inhibitor and a semicarbazide-sensitive amine oxidase inhibitor. Antihypertensive.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Siedlecki, P., et al.: J. Med. Chem. 49, 678 (2006) (2) Link, P., et al.: Cancer Res., 68, 9358 (2008) (3) Singh, N., et al.: ChemMedChem., 4, 792 (2009)

Formula: C₈H₈N₄·ClH

Colore e forma: Off-White

Peso molecolare: 196.64

Ref: TR-H716531

1-Hydrazinylphthalazine hydrochloride

CAS: 304-20-1

Formula: C₈H₉ClN₄

Purezza: 98%

Colore e forma: Solid, White to very pale yellow powder

Peso molecolare: 196.64

Ref: 10-F236804

Hydralazine hydrochloride

CAS: 304-20-1

Hydralazine hydrochloride is a drug used to treat high blood pressure. It is an inhibitor of the enzyme phosphodiesterase, which leads to increased levels of cAMP and vasodilation in the lungs. Hydralazine hydrochloride has been shown to induce renal injury, specifically by inhibiting the synthesis of prostaglandins that protect the kidneys from damage. This drug can also cause cardiac effects such as tachycardia and arrhythmias. Hydralazine hydrochloride interacts with other drugs, including Candesartan cilexetil and other drugs that inhibit phosphodiesterase, leading to an increase in blood pressure. Hydralazine hydrochloride binds to guanine nucleotide-binding proteins (G proteins) on neural cells and increases the rate constant for G protein activation.

Formula: C₈H₉ClN₄

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 196.64 g/mol

Ref: 3D-FH23871