CAS 3056-33-5

2,9-Diacetilguanina

Descrizione:

2,9-Diacetilguanina è un composto chimico che appartiene alla classe dei derivati della guanina, caratterizzato dalla presenza di due gruppi acetile attaccati agli atomi di azoto nelle posizioni 2 e 9 della struttura della guanina. Questa modifica ne migliora la solubilità e la reattività rispetto alla guanina non modificata. Il composto è tipicamente un solido cristallino bianco a bianco sporco ed è solubile in solventi polari come acqua ed etanolo. Mostra proprietà tipiche delle nucleobasi, inclusa la capacità di partecipare a legami idrogeno, che è cruciale per le sue potenziali applicazioni in biochimica e biologia molecolare. 2,9-Diacetilguanina è di interesse nella ricerca per il suo ruolo nello studio delle interazioni degli acidi nucleici e il suo potenziale utilizzo nella sintesi di analoghi di nucleosidi. Inoltre, potrebbe mostrare proprietà di fluorescenza, rendendolo utile in varie tecniche analitiche. Come per molte sostanze chimiche, la manipolazione deve essere effettuata con cautela, seguendo i protocolli di sicurezza appropriati per mitigare eventuali rischi associati al suo utilizzo.

Formula: C₉H₉N₅O₃

InChI: InChI=1/C9H9N5O3/c1-4(15)11-9-12-7-6(8(17)13-9)10-3-14(7)5(2)16/h3H,1-2H3,(H2,11,12,13,15,17)

InChI key: InChIKey=GILZZWCROUGLIS-UHFFFAOYSA-N

SMILES: C(C)(=O)N1C2=C(C(=O)N=C(NC(C)=O)N2)N=C1

Sinonimi:

• 2,9-Diacetylguanine
• 2,9-Guanine Diacetate
• 2-Acetylamino-9-Acetyl-6-Hydroxy purine
• 9-Diacetylguanine
• Acetamide, N-(9-acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)-
• Diacetyl Guanine
• Diacetylguanine
• Guanine, N,9-diacetyl-
• N,9-Diacetylguanine
• N-(9-Acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)acetamide
• N-(9-acetyl-6-oxo-6,9-dihydro-3H-purin-2-yl)acetamide
• N2,9-Diacetylguanine
• N2,N9-Diacetylguanine
• N²,9-Diacetylguanine
• N(sup 2),9-diacetylguanine
• N2,9-DIACETYLGUANINE [DIACETYL GUANINE]ACYCLOVIR
• N2,9-DIACETYLGUANINE (DIACETYL GUANINE)
• 2,9-DIACETYLGUANINE(DIACETYLGUANINE)
• 2-(Acetylamino)-9-acetyl-9H-purine-6(1H)-one
• 2-Acetamido-9-acetyl-6-oxopurine
• 2-(Acetylamino)-9-acetyl-1,9-dihydro-6H-purine-6-one
• 2-ACETYLAMINO-6-OXO-9-ACETYLPURINE
• (9-acetyl-6,9-dihydro-6-oxo-1h-purin-2-yl)acetamide
• 2,9-DIACETATEGUANINE

N2,9-Diacetylguanine

CAS: 3056-33-5

Formula: C₉H₉N₅O₃

Purezza: >95.0%(T)

Colore e forma: White to Yellow to Orange powder to crystal

Peso molecolare: 235.20

Ref: 3B-D3604

N(2),9-Diacetylguanine, 99%

CAS: 3056-33-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₉N₅O₃

Purezza: 99%

Colore e forma: White to pale cream, powder

Peso molecolare: 235.20

Ref: 02-B22709

Acetamide, N-(9-acetyl-6,9-dihydro-6-oxo-1H-purin-2-yl)-

CAS: 3056-33-5

Formula: C₉H₉N₅O₃

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 235.1995

Ref: IN-DA0030JW

N(2);9-Diacetylguanine

CAS: 3056-33-5

Formula: C₉H₉N₅O₃

Peso molecolare: 235.20

Ref: 7W-GE7096

N,9-Diacetylguanine

CAS: 3056-33-5

N,9-Diacetylguanine

Purezza: 98%

Peso molecolare: 235.20g/mol

Ref: 54-OR1014047

Acyclovir (Aciclovir) EP Impurity L

CAS: 3056-33-5

Formula: C₉H₉N₅O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 235.20

Ref: 4Z-A-047

Aciclovir EP Impurity L

CAS: 3056-33-5

Formula: C₉H₉N₅O₃

Peso molecolare: 235.20

Ref: ST-EA-CP-A8012

N2,9-Diacetylguanine

CAS: 3056-33-5

N2,9-Diacetylguanine is a synthetic molecule that can be used to inhibit the replication of herpes simplex virus. It has been found to inhibit the growth of viruses in vitro by binding to the viral DNA and inhibiting viral RNA synthesis. N2,9-Diacetylguanine is also a substrate for acetylation and may undergo this reaction with acetyl coenzyme A to form N4,9-diacetylguanine. The acetylated form of guanine inhibits the virus by blocking its ability to replicate DNA. The potential mechanism for this drug's anti-viral activity includes inhibition of the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides.

Formula: C₉H₉N₅O₃

Purezza: Min. 95%

Colore e forma: Off-White Powder

Peso molecolare: 235.2 g/mol

Ref: 3D-FD02958

N2,9-Diacetylguanine-13C2,15N

Prodotto controllato

CAS: 3056-33-5

Applications N2,9-Diacetylguanine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase.
References Kazmers, I.S., et al.: Science, 214, 1137 (1981); Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)

Formula: C₂C₇H₉₁₅NN₄O₃

Colore e forma: Neat

Peso molecolare: 238.178

Ref: TR-D335002

N2,9-Diacetylguanine

Prodotto controllato

CAS: 3056-33-5

Impurity Acicclovir EP Impurity L
Applications N2,9-Diacetylguanine (Acicclovir EP Impurity L) is used to synthesize acyclic analogues of deoxyguanosine.
References Martin, J. C., et al.: J Med Chem. 26, 759 (1983)

Formula: C₉H₉N₅O₃

Colore e forma: Neat

Peso molecolare: 235.2

Ref: TR-D335000

N-(9-Acetyl-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide

CAS: 3056-33-5

Formula: C₉H₉N₅O₃

Purezza: 96%

Colore e forma: Liquid, No data available.

Peso molecolare: 235.203

Ref: 10-F219956